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Propofol
Active Ingredients: Propofol Injection
Brand Name: Diprivan

Propofol is a drug that reduces anxiety and tension, and promotes relaxation and sleep or loss of
consciousness. Propofol provides loss of awareness for short diagnostic tests and surgical
procedures, sleep at the beginning of surgery, and supplements other types of general anesthetics.

What should my health care professional know before I receive propofol?

They need to know if you have any of these conditions:

 arrhythmia (rapid, slow, or irregular heart beat)

 blood vessel disease
 head injury
 heart disease
 high cholesterol
 pancreatitis
 seizures (convulsions)
 an unusual or allergic reaction to propofol, anesthetics, other medicines, foods, dyes, or
preservatives
 pregnant or trying to get pregnant
 breast-feeding

What drug(s) may interact with propofol?

 alcohol
 barbiturate medicines for inducing sleep or treating seizures (convulsions)
 herbal products, including St. John's wort
 medicines for anxiety or sleeping problems, such as diazepam or temazepam
 medicines for colds, breathing difficulties, or weight loss
 medicines for mental problems and psychotic disturbances
 medicines for pain

What side effects may I notice from receiving propofol?

Side effects that you should report to your prescriber or health care professional as soon as
possible:

 difficulty breathing, wheezing, swelling of the throat

 fast heartbeat, palpitations
 lightheadedness or fainting spells
  numbness or tingling in the hands or feet
 seizure (convulsion)
 skin rash, flushing (redness), or itching
 swelling or extreme pain at the injection site
 uncontrollable muscle spasm

Side effects that usually do not require medical attention (report to your prescriber or health care
professional if they continue or are bothersome):

 dizziness
 pain or irritation at the injection site

What should I watch for while taking propofol?

You will be closely monitored following administration of propofol.

Propofol is a very short-acting drug, and its effects generally wear off in just a few hours.
However, propofol may affect your ability to drive or operate machinery for several hours after
use. Do not attempt to drive yourself home if you have received propofol for minor outpatient
surgery or diagnostic tests.

Avoid alcohol, mood-altering drugs, or any other medicines for at least 24 hours after a dose of
propofol, unless approved by your prescriber or health care professional.