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Poisoning
Dr.H.Munar Lubis, SpAK
TOXICOLOGY
Ingestion
systemic effect
GIT absorption slow and uncompleted
Lung via blood stream
Aspiration
acute toxicity, hemorrhage & bronchopneumonia
death rapidly in minutes- hour
Inhalation
Gerarde (1963)
excreted through the lung >>
Kerosene poisoning
local irritation, CNS depression, degenerative
impairment & small hemorrhage in live, renal, spleen
always reversible
Clinical Presentation
1. Pharynx, esophagus, gastric and small intestine
irritation burning sensation in mouth, throat
esophagus and mucosa ulcers
2. Ventricle fibrillation rare
3. CNS : somnolent or coma, rapidly after ingestion
4. Bronchopneumonia
5. Inhalation sign: euphoria like alcohol intoxication
6. Severe Intoxication : albuminuria
Asphyxia Death
Management
Induction of emesis absolute contraindicated
Adrenalin contraindicated
Don’t give Alcohol & Mineral oil
True therapy :
1. Supportive
2. Oxygen
3. Intravenous fluid line
4. Antibiotic for prophylaxis
5. CNS symptoms caffeine