“‫”بسم هللا الرحمن الرحيم‬

Pseudomonas

Prof. Khalifa Sifaw Ghenghesh

 Pseudomonas aeruginosa

• Oxidase-positive, Strict aerobe, Gram –ve rods

• A major Cause of Nosocomial Infections.

• Infection Occur in Patients with Altered
Host Defences, Wounds or Burns.

• In Non-Hospitalized Patients:

• Vehicles of Transmission:
• LABORATORY DIAGNOSIS:
– On BA
• Irregular, -hemolytic colonies
• Oxidase-positive
• O-F test >> Aerobic

– On NA
• Bluish, irregular colonies

• TREATMENT
– Resistant to antimicrobial agents

• CONTROL
Resistance of Pseudomonas aeruginosa
isolated from different clinical sources
to antibiotics

Antibiotic No. (%) resistant

(n=235)
------------------------------------------------------
Cefsulodin 61 (26)
Gentamicin 102 (43)
Carbenicillin 113 (48)
 Resistance of Pseudomonas spp isolated
from hospital and community cockroaches
to antibiotics
No. (%) resistant
Antibiotic Hospital Community Total
(n=34) (n=9) (n=43)
---------------------------------------------------------------------------------
Ampicillin 33 (97) 9 (100) 42 (97)
Amoxicillin- 33 (97) 9 (100) 43 (100)
clavulanic acid
Ceftazidime 0 (0.0) 0 (0.0) 0 (0.0)
Cephalothin 34 (100) 9 (100) 43 (100)
Chloramphenicol 33 (97) 9 (100) 42 (97)
Gentamicin 4 (12) 0 (0.0) 4 (9.5)
Nalidixic acid 34 (100) 9 (100) 43 (100)
Nitrofurantoin 34 (100) 9 (100) 43 (100)
Ciprofloxacin 0 (0.0) 0 (0.0) 0 (0.0)
Tetracycline 32 (94) 9 (100) 41 (95.3)
Trimethoprim- 34 (100) 9 (100 43 (100)
sulphamethoxazole