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  • Nucleophilic Substitution-Elimination Decision Matrix

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    SN1, SN2, E1, E2 Decision Matrix Use with caution. Rely on your knowledge of the four parameters (substrate, solvent, nucleophile, and Leaving group) to predict possible reactions that will occur.

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    SN1, SN2, E1, E2 Decision Matrix Use with caution. Rely on your knowledge of the four parameters (substrate, solvent, nucleophile, and Leaving group) to predict possible reactions that will occur.

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    17 views1 page

    Nucleophilic Substitution-Elimination Decision Matrix

    Uploaded by

    ccentellav
    SN1, SN2, E1, E2 Decision Matrix Use with caution. Rely on your knowledge of the four parameters (substrate, solvent, nucleophile, and Leaving group) to predict possible reactions that will occur.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
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    SN1, SN2, E1, E2 Decision Matrix

    Use with caution. Rely on your knowledge of the four parameters (Substrate, Solvent, Nucleophile, and Leaving Group) to predict possible reactions that will occur.

    Substrate

    1O
    Yes

    2O
    Allylic or Benzylic? No No SN2 Yes Strong Base No Yes

    3O

    No SN1 or E1

    SN1 or E1 Strong Base No

    Nucleophile

    Yes

    Strong Base

    No

    SN 2

    SN2 w/ some E2

    E2

    Solvent
    Protic E2 Solvent Aprotic SN 2 Protic E2 Solvent Aprotic SN 2 Yes SN 1 Hydroxylic Solvent No

    SN1 or E1

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