Scribd Logo
Upload

Welcome to Scribd!

  • Iv - Pathophysiology: Predisposing Factors: Precipitating Factor

    Uploaded by

    Jatevenzche Lao
    19 views1 page
    Obesity, poor nutrition, pre-existing conditions, and placental defects can precipitate preeclampsia by impairing placental implantation and endothelial function, increasing platelet activation and reducing blood flow. This causes placental ischemia and injury, releasing factors that cause widespread maternal syndrome of hypertension, increased vascular resistance, and organ damage like kidney impairment from decreased filtration and increased reabsorption.

    Original Description:

    Original Title

    2

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    DOC, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    Obesity, poor nutrition, pre-existing conditions, and placental defects can precipitate preeclampsia by impairing placental implantation and endothelial function, increasing platelet activation and reducing blood flow. This causes placental ischemia and injury, releasing factors that cause widespread maternal syndrome of hypertension, increased vascular resistance, and organ damage like kidney impairment from decreased filtration and increased reabsorption.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    19 views1 page

    Iv - Pathophysiology: Predisposing Factors: Precipitating Factor

    Uploaded by

    Jatevenzche Lao
    Obesity, poor nutrition, pre-existing conditions, and placental defects can precipitate preeclampsia by impairing placental implantation and endothelial function, increasing platelet activation and reducing blood flow. This causes placental ischemia and injury, releasing factors that cause widespread maternal syndrome of hypertension, increased vascular resistance, and organ damage like kidney impairment from decreased filtration and increased reabsorption.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    IV.

    PATHOPHYSIOLOGY
    Precipitating factor: Obesity Poor maternal nutrition Pre-existing hypertension Renal disease Defective placental implantation Endovascular trophoblastic cells invade the maternal spiral arteries Release of placental factor Fibrin, platelets and lipophages aggregates

    Predisposing factors: Age-39 years old Hereditary -HPN

    Replacement of endothelium, destruction of medical musculoelastic tissue, and fibrinoid change in the vessel wall

    Increased platelet activation

    Acute atherosis partially or completely blocking the arterioles

    Increased thrombosane Placental infraction vasospasm Fetal distress Endothelial dysfunction Fetal death

    Placental ischemia

    Hypertension

    vasoconstiction

    Increase d BP=160/ 110mm Hg

    Reduced perfusion of affected organs

    kidney

    Decrease GFR

    Increase permeability of the glomerular membrane

    Increase reabsorption in tubules

    Decrease urine output Increase uric acid Increase creatine

    proteinuria

    Increase sodium retention + H2O

    LEGEND: - Process - Signs & symptoms - Medication - Pathophysiological pathways

    edema

    You might also like