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    Beta-lactams like penicillin and vancomycin prohibit bacterial cell wall synthesis by interfering with peptidoglycan production, primarily used against gram-positive bacteria like Staphylococcus and Streptococcus. Tetracyclines inhibit bacterial protein synthesis while quinolones and metronidazole block DNA synthesis, with quinolones used against E. coli and metronidazole against vaginal infections. Rifamycin targets RNA synthesis in mycobacteria and rifamycins are used to treat tuberculosis and leprosy.

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    Beta-lactams like penicillin and vancomycin prohibit bacterial cell wall synthesis by interfering with peptidoglycan production, primarily used against gram-positive bacteria like Staphylococcus and Streptococcus. Tetracyclines inhibit bacterial protein synthesis while quinolones and metronidazole block DNA synthesis, with quinolones used against E. coli and metronidazole against vaginal infections. Rifamycin targets RNA synthesis in mycobacteria and rifamycins are used to treat tuberculosis and leprosy.

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    27 views1 page

    Antibiotics

    Uploaded by

    api-3699215
    Beta-lactams like penicillin and vancomycin prohibit bacterial cell wall synthesis by interfering with peptidoglycan production, primarily used against gram-positive bacteria like Staphylococcus and Streptococcus. Tetracyclines inhibit bacterial protein synthesis while quinolones and metronidazole block DNA synthesis, with quinolones used against E. coli and metronidazole against vaginal infections. Rifamycin targets RNA synthesis in mycobacteria and rifamycins are used to treat tuberculosis and leprosy.

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    Antibiotics – against bacteria

    Name Basic action Detailed action Used against

    Prohibits cell wall synthesis by Gram +ve.


    Beta-lactams Cell Wall
    interfering with peptidoglycan synthesis. Some Staph and Strep.

    Prohibits cell wall synthesis by Gram +ve.


    Vancomycin Cell Wall
    interfering with peptidoglycan synthesis. Staph

    Stops bacteria from synthesising Chlamydia,


    Tetracyclines Protein
    protein. Strep pneumoniae
    Gram –ve.
    Quinolones DNA Stops bacteria from synthesising DNA. E-coli (urinary tract
    infections)

    Metronidazole DNA Stops bacteria from synthesising DNA. Vaginal infections.

    Mycobacteria.
    Rifamycin RNA Blocks RNA synthesis in bacteria.
    Leprosy and TB

    Trimethoprim
    Used in combination to
    Folic Acid Interferes with folic acid production. treat pneumocystis
    infections.
    Sulphonamides

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