Name of Patient Diagnosis Doctor  Drug Data Generic Name

Anding, Jessica Donaire R/O conjunctivitis secondary to trauma Dr. Tipgos Classification Therapeutic: Antibiotic Pharmacologic aminopenicillins

Age Sex Date of Admission Indication  General Indications To treat ear, nose, throat, GU tract, skin, and soft-tissue infections caused by susceptible grampositive and gramnegative organisms, To treat tonsillitis or pharyngitis caused by Streptococcus pyogenes, To treat lower respiratory tract infec tions caused by susceptible gram-positive and gramnegative organisms,

5 yrs. 5 months Female Not yet admitted Contraindications Hypersensitivity to amoxicillin or its components  Precaution Severe renal insufficiency (↓ dose if CCr <30 mL/min) • Infectious mononucleosis, acute lymphocytic leukemia, or cytomegaloviru s infection (↑ risk of rash) • OB: Lactation: Has been used safely  Drug interaction -drug to drug allopurinol: Increased risk of rash

Height Weight Body Build

105.5 cm 17 kg sthenic

amoxicillin trihydrate (amoxycillin) Trade Name Amoxil, Apo-Amoxi (CAN), DisperMox, Moxatag, Novamoxin (CAN), Nu-Amoxi (CAN), Polymox, Trimox, Wymox  Patients Dose Suspension for 7 days  Minimum Dose Children age 12 wk and over weighing less than 20 kg. 20 mg/kg daily in divided doses every 8 hr  Maximum Dose 500 mg every 8 hr or 875 mg every 12 hr  Availability and color

Mechanism of Action  Pharmacokinetics A Well absorbed from duodenum (75–90%). More resistant to acid inactivation than other penicillins D Diffuses readily into most body tissues and fluids. CSF penetration increased when meninges are inflamed. Crosses placenta; enters breast milk in small amounts M&E 70% excreted unchanged in the urine; 30% metabolized by the liver  Onset Unknown Peak Unknown

Adverse Reaction Nursing Responsibilities CNS: Agitation,  Before anxiety, behavior • Patients with changes, mononucleosis confusion, shouldn’t dizziness, receive amoxicillin insomnia, because this class of reversible drugs may cause an hyperactivity, erythematous rash. seizures • Use drug cautiously in CV: patients with hepatic Hypersensitivity impairment. vasculitis • Monitor hepatic and EENT: Black, renal function and CBC, hairy tongue; as ordered, in patients mucocutaneous on prolonged therapy. candididasis; • use cautiously in breasttooth feeding and elderly discoloration patients. GI: Diarrhea, • Expect to start therapy diarrhea related to before culture and Clostridium sensitivity test results difficile, elevated are known. liver enzymes, as ordered. hemorrhag- ic or PATIENT TEACHING pseudomembrano • Tell patient to refrigerate us colitis, reconstituted susjaundice, hepatic pension and to shake dysfunction, well before each use.

or cold drink (milk.CAPSULES. directly on child’s anemia (including tongue to swallow. • Don’t confuse arthritis. ginger ale. and amoxicillin tablets for . generalized more water to the glass. sulfon.ate toxicity oral contraceptives with estrogen: Possibly 76 amphetamine sulfate reduced effectiveness of contraceptive probenecid: Increased amoxicillin effects nausea. vomiting • When amoxicillin GU: Crystalluria. If hemolytic this doesn’t work. thrombocytopenic • Instruct patient using purpura DisperMox tablets to SKIN: Erythema place one tablet and multiforme. POWDER OR TABLETS FOR ORAL SUSPENSION. water) thrombocytopenia and have child drink it . tablets and tablets for urticaria Other: oral suspension contain Allergic reaction.matous and drink again to pustulosis. parents to mix dose of eosinophilia. TABLETS  Routes of administration P.7– 1. CHEWABLE TABLETS. erythromycins. juice. exanthe.  Duration\ 6–8 hr  Drug Half Life Neonates: 3. ORAL SUSPENSION.O. phenylalanine. toxic During epidermal • Be aware that chewable necrolysis. Infants and Children: 1–2 hr.cytosis. • Tell patient to chew or serum crush chewable tablets sicknesslike and not to swallow them reaction (such as whole. PEDIATRIC DROPS.amides. suspension with formula granulo. amoxicillin tablets with myalgia. tell anemia). fever. immediately. instruct HEME: parents to place it Agranulocytosis.4 hr Treatment of » Skin and skin structure infections  Patients Actual Indication Treatment of » Skin and skin structure infections chloramphenicol. ensure delivery of full Stevens-Johnson dose. syn. arthralgia. fruit leukopenia. Adults: 0. drink maculopapular entire mix ture. suspension is prescribed vaginal mycosis for a child. add rash. rash. tetracyclines: Reduced bactericidal effect of amoxicillin methotrexate: Increased risk of methotrex.7 hr.drome. anaphylaxis. about 2 teaspoonfuls of erythematous water in a glass.

even if he feels better. • Monitor patient for superinfection. If it occurs.urticaria) oral suspension (DisperMox). • Urge patient to tell prescriber about diarrhea that’s severe or lasts longer than 3 days. • To prevent infection from recurring. Remind patient that watery or bloody . stop amoxicillin immediately and provide emergency care as indicated and ordered. expect to discontinue drug and provide treatment After • Teach patient to report adverse reactions • notify prescriber if infection worsens or doesn’t improve after 72 hours. urge patient to take amoxicillin for full length of time prescribed. • If allergic reaction occurs. They’re not interchangeable.

Sanoski.A. Source: Deglin. 2010 Source: Deglin. Vallerand.drugguide . 2010 Source: http://www. 2010 Source: http://www. requiring prompt treatment. Sanosk i. Davis’s Drug Guide for Nurses F. D avis’s Drug Guide for Nurses F. Davis Company. Davis’s Drug Guide for Nurses F. Davis’ s Drug Guide for Nurses F. Sanos ki.A.A. • Monitor patient closely for diarrhea.A. 2010 Source: Deglin. Davis Company. 2010 .stools can occur 2 or more months after antibiotic therapy and may be serious. Sanoski. Vallerand. Vallerand. which may indicate pseudomembranous colitis • Expect treatment that lasts at least 10 days for hemolytic streptococci infections.com/ddo/ub/ view/Davis-DrugGuide/51047/4/a moxicillin?q=amo xicillin Source: Deglin. Sanos ki.A. Vallerand. Vallerand. Davis Company. Davis Company.drugg uide. Davis’s Drug Guide for Nurses F. Davis Company.com/ddo/ub/view/Da vis-DrugGuide/51047/3/amoxi cillin?q=amoxicillin Source: Deglin.

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