Specific Inhibitors of MEK/MAPK Pathway Unable to read this email? View an online version.

Solutions to Signal Transduction Research

Dear Customer,

Based on your research area, Selleck has special recommendations for you on our inhibitors of the MEK/MAPK pathway.

Cat. No.
S1531

Inhibitor Name
BIX 02189

Purity
>99%

More Inhibitors of the MEK/MAPK Pathway by Product

Bioactivity: BIX 02189 is a selective MEK5/MAPK5 inhibitor with an IC50 of 59 nM. S1561 BMS 777607 >99%

AS703026 PD0325901

CI-1040 (PD184352) PLX-4032 (RG7204)

Bioactivity: BMS 777607 is a Small-Molecule Met Kinase Inhibitor with an IC50 of < 0.1 M. MEK S1008 AZD6244 (Selumetinib) >99% B-Raf Ras

by Target p38 MAPK JNK

Bioactivity: AZD6244, also known as Selumetinib, ARRY142886 and AZD6244, is MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nm.

Applications & Feedbacks

More Products of Available Signal Pathways by Category Inhibitors siRNAs Antibodies Peptides

You may also feel interested in ... E-catalog Download BIX 02189 AZD6244 (Selumetinib) More Feedbacks Free Sample Program Gift Coupons

Papers Using Selleck Inhibitors

1. Nazarian, R., et al. Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation. Nature. 2010 Dec 16; 468(7326): 973-7. 2. Aziz, S.A., et al. Vertical targeting of the phosphatidylinositol-3 kinase pathway as a strategy for treating melanoma. Clin Cancer Res. 2010 Dec 15; 16(24): 6029-39.

Points Program

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