Generic Name Trade Classification Dose Route Time/frequency Hydrocodone/acetaminophen Name opioid 7.5/550 PO Q 4˚ PRN Lortab agonists/nonopioid 1-2 tab analgesic combinations Peak Onset Duration Normal dose range 30-60 min 10-30 min 4-6 hr 2.5-10 mg q 3-6 hr as needed; if using combination products, acetaminophen or aspirin dosage should not exceed 4 g/day Mechanism of action and indications Nursing Implications (what to focus on) (Why med ordered) Contraindications/warnings/interactions Bind to opiate receptors in the CNS. Alter the perception of and Hypersensitivity, hypothyroidism response to painful stimuli while producing generalized CNS depression Common side effects confusion, sedation, hypotension, constipation Moderate pain Interactions with other patient drugs, OTC or herbal medicines Lab value alterations caused by medicine (ask patient specifically) May cause increased plasma amylase and lipase Lorazepam concentrations Be sure to teach the patient the following about this medication Advise patient to take medication exactly as directed and not to take more than the recommended amount. Severe and permanent liver damage may result from prolonged use or high doses of acetaminophen. Renal damage may occur with prolonged use of acetaminophen or aspirin. Doses of nonopioid agents should not exceed the maximum recommended daily dose Instruct patient on how and when to ask for pain medication May cause drowsiness or dizziness. Advise patient to call for assistance when ambulating Advise patient to change positions slowly to minimize orthostatic hypotension Encourage patient to turn, cough, and breathe deeply every 2 hr to prevent atelectasis Advise patient that good oral hygiene, frequent mouth rinses, and sugarless gum or candy may decrease dry mouth Nursing Process- Assessment Assessment Evaluation (Pre-administration assessment) Why would you hold or not give this Assess blood pressure, pulse, and respirations before and med? Check after giving periodically during administration. Before administering, clarify all Decrease in severity of Assess type, location, and intensity of pain prior to and 1 hr ambiguous orders; have second pain without a (peak) following administration. practitioner independently check significant alteration in original order and dose calculations, level of consciousness If respiratory rate is <10/min, assess or respiratory status level of sedation. Physical stimulation may be sufficient to prevent significant hypoventilation. Reports no pain