NATIONAL

ESSENTIAL MEDICINES
LIST OF PAKISTAN

Ministry of Health
Government of Pakistan
Islamabad

2007

CONTENTS
PREFACE.

NATIONAL ESSENTIAL MEDICINES LIST

FOURTH REVISION

Explanatory Notes .......................................................... ii

1:

2:

ANAESTHETICS............................................................ 1
1.1

General Anaesthetics and Oxygen..................... 1

1.2

Local Anaesthetics..............................................1

1.3

Preoperative medication and sedation for short term procedure1

ANALGESICS, ANTIPYRETICS, NONSTEROIDAL ANTI-INFLAMMATORY MEDICINES, MEDICINES USED TO TREAT GOUT

AND DISEASE MODIFYING AGENTS IN RHEMATOID DISORDERS..2

3:

2.1

Non-Opioids and Non steroidal Anti inflammatory medicines..2

2.2

Opioid Analgesics ..............................................2

2.3

Medicines used to treat gout. 2

2.4

Disease modifying agents used in rheumatoid disorders (DMARDs)2

ANTI-ALLERGICS AND MEDICINES USED IN

ANAPHYLAXIS..............................................................3

4:

ANTIDOTES AND OTHER SUBSTANCES USED IN POISONINGS.3

4.1

Non-specific..3

4.2

Specific.3

5:

ANTICONVULSANTS/ANTIEPILEPTICS ...................4

6:

ANTI-INFECTIVE MEDICINES ...................................5

6.1 Anthelmintics ............................................................5
6.1.1
6.2

Intestinal Anthelminthics5

Antibacterials......................................................5

6.2.1 Beta Lactam medicines......................................5

6.2.2 Other Antibacterials.6
6.2.3 Antileprosy medicines.7
6.2.4 Antituberculosis medicines7
6.3

Antifungal Medicines .........................................9

6.4

Antiviral Medicines ............................................9

6.4.1 Antiherpes Medicines..9

6.4.2 Antiretovirals..9
6.4.2.1 Nucleoside/Nucleotide reverse transcriptase inhibitors..9
6.4.2.2 Non-nucleoside reverse transcriptase inhibitors..10
6.4.2.3 Protease Inhibitors.10
6.4.3 Other Antivirals11
6.5

Antiprotozoal Medicines..11

6.5.1 Antiamoebic and Antigiardiasis Medicines11

6.5.2 Antileishmaniasis Medicines12
6.5.3 Antimalarial Medicines12
6.5.3.1 For Curative Treatment12
6.5.3.2 For Prophylaxis.. 13
6.5.4 Antipneumocystosis and Antitoxoplasmosis Medicines..13
7.

ANTIMIGRAINE MEDICINES.13

7.1

For Treatment of Acute Attack.13

7.2

For Prophylaxis.14

8.

ANTINEOPLASTIC, IMMUNOSUPRESSIVES..14

8.1

Immunosuppressive Medicines..14

8.2

Cytotoxic Medicines.14

8.3

Hormones and Antihormones.15

9.

ANTIPARKINSONISM MEDICINES..15

10.

MEDICINES AFFECTING THE BLOOD.15

10.1 Antianaemia Medicines ....................................15

10.2 Medicines Affecting Coagulation15
11.

BLOOD PRODUCTS AND PLASMA SUBSTITUTES.16

11.1 Plasma Substitutes16

11.2 Plasma Fractions for Specific Use16
12.

CARDIOVASCULAR MEDICINES16

12.1 Antianginal Medicines..16

12.2 Antiarrhythmic Medicines.16
12.3 Antihypertensive Medicines.17
12.4 Medicines Used in Heart Failure18
12.5 Antithrombotic Medicines.18
12.6 Lipid-Lowering Agents18
13.

DERMATOLOGICAL MEDICINES (TOPICAL)..18

13.1 Antifungal medicines.18

13.2 Anti-Infective Medicines19

13.3 Anti-Inflammatory and Antipruritic Medicines..19

13.4 Astringent Medicines19
13.5 Medicines Affecting Skin Differentiation and Proliferation19
13.6 Scabicides and Pediculicides.19
14.

DIAGNOSTIC AGENTS.20

14.1 Ophthalmic Medicines20

14.2 Radiocontrast Media20
15.

DISINFECTANTS AND ANTISEPTICS.20

15.1 Antiseptics.20
15.2 Disinfectants20
16.

DIURETICS .....................................................20

17.

GASTROINTESTINAL MEDICINES..21

17.1 Antacids and other Antiulcer Medicines21

17.2 Antiemetic Medicines21
17.3 Anti-Inflammatory medicines..21
17.4 Laxatives21
17.5 Medicines used in Diarrhoea..21
17.5.1 Oral Rehydration21
17.5.2 Medicines for Diarrhoea in Children22
17.5.3 Antidiarrhoeal (symptomatic) Medicines in Adults..22
18.

HORMONES, OTHER ENDOCRINE MEDICINES AND CONTRACEPTIVES22

18.1 Androgens22
18.2 Contraceptives..22
18.2.1 Oral Hormonal Contraceptives..22
18.2.2 Injectable Hormonal Contraceptives.23
18.2.3 Intrauterine Devices..23
18.2.4 Barrier Methods................................................23
18.2.5 Implantable Contraceptives..23
18.3 Estrogens23
18.4 Insulins and other Antidiabetic Agents23
18.5 Ovulation Inducers.23
18.6 Progestogens.24
18.7 Thyroid Hormones and Antithyroid Medicines.24
19. IMMUNOLOGICALS..24
19.1 Diagnostic Agents24
19.2 Sera and Immunoglobulins24

19.3 Vaccines25
20.

MUSCLE RELAXANTS (PERIPHERALLY-ACTING) AND CHOLINESTERASE

INHIBITORS ...................................................26

21.

OPHTHALMOLOGICAL PREPARATIONS26

21.1 Anti-Infective Agents26

21.2 Anti-Inflammatory Agents..26
21.3 Local Anaesthetics..26
21.4 Miotics and Antiglaucoma Medicines..26
21.5 Mydriatics.26
22.

OXYTOCICS AND ANTIOXYTOCICS..27

22.1 Oxytocics27
22.2 Antioxytocics (Tocolytics)..27
23.

PERITONEAL DIALYSIS SOLUTION.27

24.

PSYCHOTHERAPEUTIC MEDICINES..27

24.1 Medicines used in Psychotic Disorders..27

24.2 Medicines used in Mood Disorders.27
24.2.1 Medicines used in Depressive Disorders.27
24.2.2 Medicines used in Bipolar Disorders.27
24.3 Medicines used in Generalized Anxiety and Sleep Disorders28
24.4 Medicines used for Obsessive Compulsive Disorders and Panic Attacks28
24.5 Medicines used in Substance Dependence Programmes28
25.

MEDICINES ACTING ON THE RESPIRATORY TRACT..28

25.1 Antiasthmatic and Medicines for Chronic Obstructive Pulmonary Disease..28

25.2 Other Medicines Acting on the Respiratory Tract..28
26.

SOLUTIONS CORRECTING WATER, ELECTROLYTE AND ACID-BASE

DISTURBANCES.29

26.1 Oral.29
26.2 Parenteral29
26.3 Miscellaneous..29
27.

VITAMINS AND MINERALS..29

INDEX ....................................................................... ..31

PREFACE
After the second World War the development and emergence of miracle
medicines like antibiotics brought a revolution in the medical care. The obvious
effectiveness of these new pharmaceuticals and intensive marketing efforts
combined to catalyze wide spread use of modern medicine. A rapidly growing
and profitable industry, together with an enthusiastic but largely uninformed
audience and an unregulated market, resulted in excess of promotion and
consumption alowgwith inflated level of expenditure. However, by 1970s it had
become clear that least advantageous nations were not even meeting the basic
needs of their people for essential life saving and health promoting medicines. As
a result gradually a number of countries started concentrating on the
development of a basic list of reliable medicines to meet the most vital basic
needs of their people.
A World Health Organization (WHO) Committee of Experts met in 1977 to
determine the number of medicines, which were actually needed to ensure a
reasonable level of health care for as many people as possible. Consequently,
the first Model List of Essential medicines was finalized in the same year. This list
is being updated regularly by the WHO and is intended to be used as a guideline
and provide basis for member countries to identify their own priorities and make
their own selection. Through 1970s and 1980s the WHO started promotion of the
concept of Essential medicines Program in order to redress this imbalance. The
program aimed at reduction in the number of medicines purchased/used by the
hospitals/institutions to a minimum possible level in order to make best use of
limited public funds.
Essential medicines as defined by WHO are those that satisfy the health care
needs of majority of the population. They should therefore be available at all
times in adequate amounts and in the appropriate dosage forms.
The National Essential medicines List (NEML) of Pakistan was first prepared in
1994 in consultation with relevant experts. The list was previously reviewed in
1995, 2000 and 2003. The present list is the fourth revision containing 335
medicines of different pharmacological classes.
The health sector in general and public health sector in particular is expected to
seriously consider adopting this list. The provincial health departments can play a
pivotal role to encourage the hospitals/institutions for making bulk purchases
from within this list. We hope that this list will find more acceptance among health
care professionals.

Maj. Gen. Shahida Malik HI (M)

Director General Health

ExplanatoryNotes
Thecorelistpresentsalistofminimummedicineneedsforabasichealthcare
system,listingthemostefficacious,safeandcosteffectivemedicinesforpriority
conditions.Priorityconditionsareselectedonthebasisofcurrentandestimated
futurepublichealthrelevance,andpotentialforsafeandcosteffectivetreatment.
Thecomplementarylistpresentsessentialmedicinesforprioritydiseases,for
whichspecializeddiagnosticormonitoringfacilities,and/orspecialistmedical
care,and/orspecialisttrainingareneeded.
Thesquareboxsymbol()isprimarilyintendedtoindicatesimilarclinical
performancewithinapharmacologicalclass.

Dosageformsofmedicinesarelistedinalphabeticalorderandthereisno
implicationofpreferenceforoneformoveranother.Standardtreatment
guidelinesshouldbeconsultedforinformationonappropriatedosageforms.
Entriesofthetypeoralliquidareintendedtopermitanysolution,suspensionor
otherformofliquid.Granulesforreconstitutionasanoralliquidmaysubstitute
fororalliquids,andtypicallycarrybenefitsintheformofbetterstabilityand
lowertransportcosts.Ifmorethanonetypeoforalliquidisavailableonthe
samemarket(e.g.solution,suspension,granulesforreconstitution),theymaybe
interchangedandinsuchcasesshouldbebioequivalent.Itispreferablethatoral
liquidsdonotcontainsugarandthatsolutionsforchildrendonotcontain
alcohol.
Entriesofthetypetabletareintendedtoallowvariousformsofimmediaterelease
tabletsuchasuncoated,filmcoated,crushable,chewable,dispersibleetc.Enteric
coating,ontheotherhand,modifiesdrugrelease,andentericcoatedproductsare
amodifiedreleasedosageform.Crushable,chewableanddispersibletabletsmay
beeasiertoadministertopaediatricpopulationsandtotheelderly.

1. ANAESTHETICS
1.1 General anaesthetics and oxygen
halothane

Inhalation.

ketamine

Injection:50mg(ashydrochloride)/mlin10mlvial.

nitrousoxide

Inhalation.

oxygen

Inhalation(medicinalgas).

thiopental

Powderforinjection:0.5g;1.0g(sodiumsalt)inampoule.

1.2 Local anaesthetics

Injection:0.25%;0.5%(hydrochloride)invial.
bupivacaine

Injectionforspinalanaesthesia:0.5%(hydrochloride)in
4mlampouletobemixedwith7.5%glucosesolution.
Injection:1%;2%(hydrochloride)invial.

lidocaine

Injectionforspinalanaesthesia:5%(hydrochloride)in2ml
ampouletobemixedwith7.5%glucosesolution.
Topicalforms:24%(hydrochloride).

lidocaine+epinephrine
(adrenaline)

Dentalcartridge:2%(hydrochloride)+epinephrine1:80000.

Injection:1%;2%(hydrochloride)+epinephrine1:200000in
vial.

ComplementaryList
Injection:30mg(hydrochloride)/mlin1mlampoule.
ephedrine

(Foruseinspinalanaesthesiaduringdelivery,toprevent
hypotension).

1.3 Preoperative medication and sedation for short-term procedures

atropine
diazepam

Injection:1mg(sulfate)in1mlampoule.
Injection:5mg/mlin2mlampoule.
Tablet:5mg.

morphine

Injection:10mg(sulfateorhydrochloride)in1mlampoule.

promethazine

Oralliquid:5mg(hydrochloride)/5ml.

2. ANALGESICS, ANTIPYRETICS, NON-STEROIDAL ANTIINFLAMMATORY MEDICINES (NSAIMs), MEDICINES USED TO TREAT

GOUT AND DISEASE MODIFYING AGENTS IN RHEUMATOID
DISORDERS (DMARDs)
2.1 Non-opioids and non-steroidal anti-inflammatory medicines (NSAIMs)
acetylsalicylicacid
ibuprofen

Suppository:50150mg.
Tablet:100500mg.
Tablet:200mg;400mg.
Oralliquid:125mg/5ml.
Suppository:100mg.

paracetamol*

Tablet:100500mg.
*Notrecommendedforantiinflammatoryuseduetolack
ofprovenbenefittothateffect.

diclofenac(asSodium) 75mg/3mlinj.(assodium)
2.2 Opioid analgesics
codeine

Tablet:30mg(phosphate).
Injection:10mg(morphinehydrochlorideormorphine
sulfate)in1mlampoule.

morphine

Oralliquid:10mg(morphinehydrochlorideormorphine
sulfate)/5ml.
Tablet:10mg(morphinesulfate).
Tablet(prolongedrelease):10mg;30mg;60mg(morphine
sulfate).

Pethidine

50 mg/ml inj. (as hydrochloride)

2.3 Medicines used to treat gout

allopurinol

Tablet:100mg.

2.4 Disease modifying agents used in rheumatoid disorders (DMARDs)

chloroquine

Tablet:100mg;150mg(asphosphateorsulfate).

ComplementaryList
azathioprine

Tablet:50mg.

methotrexate

Tablet:2.5mg(assodiumsalt).

penicillamine

Capsuleortablet:250mg.

sulfasalazine

Tablet:500mg.

1. ANAESTHETICS
1.1 General anaesthetics and oxygen
halothane

Inhalation.

ketamine

Injection:50mg(ashydrochloride)/mlin10mlvial.

nitrousoxide

Inhalation.

oxygen

Inhalation(medicinalgas).

thiopental

Powderforinjection:0.5g;1.0g(sodiumsalt)inampoule.

1.2 Local anaesthetics

Injection:0.25%;0.5%(hydrochloride)invial.
bupivacaine

Injectionforspinalanaesthesia:0.5%(hydrochloride)in
4mlampouletobemixedwith7.5%glucosesolution.
Injection:1%;2%(hydrochloride)invial.

lidocaine

Injectionforspinalanaesthesia:5%(hydrochloride)in2ml
ampouletobemixedwith7.5%glucosesolution.
Topicalforms:24%(hydrochloride).

lidocaine+epinephrine
(adrenaline)

Dentalcartridge:2%(hydrochloride)+epinephrine1:80000.

Injection:1%;2%(hydrochloride)+epinephrine1:200000in
vial.

ComplementaryList
Injection:30mg(hydrochloride)/mlin1mlampoule.
ephedrine

(Foruseinspinalanaesthesiaduringdelivery,toprevent
hypotension).

1.3 Preoperative medication and sedation for short-term procedures

atropine
diazepam

Injection:1mg(sulfate)in1mlampoule.
Injection:5mg/mlin2mlampoule.
Tablet:5mg.

morphine

Injection:10mg(sulfateorhydrochloride)in1mlampoule.

promethazine

Oralliquid:5mg(hydrochloride)/5ml.

2. ANALGESICS, ANTIPYRETICS, NON-STEROIDAL ANTIINFLAMMATORY MEDICINES (NSAIMs), MEDICINES USED TO TREAT

GOUT AND DISEASE MODIFYING AGENTS IN RHEUMATOID
DISORDERS (DMARDs)
2.1 Non-opioids and non-steroidal anti-inflammatory medicines (NSAIMs)
acetylsalicylicacid
ibuprofen

Suppository:50150mg.
Tablet:100500mg.
Tablet:200mg;400mg.
Oralliquid:125mg/5ml.
Suppository:100mg.

paracetamol*

Tablet:100500mg.
*Notrecommendedforantiinflammatoryuseduetolack
ofprovenbenefittothateffect.

diclofenac(asSodium) 75mg/3mlinj.(assodium)
2.2 Opioid analgesics
codeine

Tablet:30mg(phosphate).
Injection:10mg(morphinehydrochlorideormorphine
sulfate)in1mlampoule.

morphine

Oralliquid:10mg(morphinehydrochlorideormorphine
sulfate)/5ml.
Tablet:10mg(morphinesulfate).
Tablet(prolongedrelease):10mg;30mg;60mg(morphine
sulfate).

Pethidine

50 mg/ml inj. (as hydrochloride)

2.3 Medicines used to treat gout

allopurinol

Tablet:100mg.

2.4 Disease modifying agents used in rheumatoid disorders (DMARDs)

chloroquine

Tablet:100mg;150mg(asphosphateorsulfate).

ComplementaryList
azathioprine

Tablet:50mg.

methotrexate

Tablet:2.5mg(assodiumsalt).

penicillamine

Capsuleortablet:250mg.

sulfasalazine

Tablet:500mg.

3. ANTIALLERGICS AND MEDICINES USED IN ANAPHYLAXIS

chlorphenamine

Injection:10mg(hydrogenmaleate)in1mlampoule.
Tablet:4mg(hydrogenmaleate).

dexamethasone

Injection:4mgdexamethasonephosphate(asdisodiumsalt)
in1mlampoule.

epinephrine(adrenaline)

Injection:1mg(ashydrochlorideorhydrogentartrate)in
1mlampoule.

hydrocortisone

Powderforinjection:100mg(assodiumsuccinate)invial.
Tablet:5mg;25mg

prednisolone*

*Thereisnoevidenceforcompleteclinicalsimilarity
betweenprednisoloneanddexamethasoneathighdoses.

4. ANTIDOTES AND OTHER SUBSTANCES USED IN POISONINGS

4.1 Non-specific
charcoal,activated

Powder.

4.2 Specific
acetylcysteine

Injection:200mg/mlin10mlampoule.

atropine

Injection:1mg(sulfate)in1mlampoule.

calciumgluconate

Injection:100mg/mlin10mlampoule.

deferoxamine

Powderforinjection:500mg(mesilate)invial.

dimercaprol

Injectioninoil:50mg/mlin2mlampoule.

DLmethionine

Tablet:250mg.

methylthioniniumchloride
(methyleneblue)

Injection:10mg/mlin10mlampoule.

naloxone

Injection:400micrograms(hydrochloride)in1ml
ampoule.

penicillamine

Capsuleortablet:250mg.

potassiumferric
hexacyanoferrate(II)2H20

Powderfororaladministration.

(Prussianblue)
sodiumcalciumedetate

Injection:200mg/mlin5mlampoule.

sodiumnitrite

Injection:30mg/mlin10mlampoule.

sodiumthiosulfate

Injection:250mg/mlin50mlampoule.

5. ANTICONVULSANTS/ANTIEPILEPTICS
Oralliquid:100mg/5ml.
carbamazepine

Tablet(chewable):100mg;200mg.
Tablet(scored):100mg;200mg.

diazepam

Injection:5mg/mlin2mlampoule(intravenousor
rectal).
Injection:500mg/mlin2mlampoule;500mg/mlin
10mlampoule.

magnesiumsulfate*
*Foruseineclampsiaandseverepreeclampsiaand
notforotherconvulsantdisorders.
Injection:200mg/ml(phenobarbitalsodium).
phenobarbital

Oralliquid:15mg/5ml(asphenobarbitalor
phenobarbitalsodium).
Tablet:15100mg(phenobarbital).
Capsule:25mg;50mg;100mg(sodiumsalt).
Injection:50mg/mlin5mlvial(sodiumsalt).
Oralliquid:2530mg/5ml.*

phenytoin

Tablet:25mg;50mg;100mg(sodiumsalt).
Tablet(chewable):50mg.
*Thepresenceofboth25mg/5mland30mg/5ml
strengthsonthesamemarketwouldcauseconfusionin
prescribinganddispensingandshouldbeavoided.
Oralliquid:200mg/5ml.

valproicacid

Tablet(crushable):100mg.
Tablet(entericcoated):200mg;500mg(sodium
valproate).

ComplementaryList

Capsule:250mg.
ethosuximide
Oralliquid:250mg/5ml.

6. ANTI-INFECTIVE MEDICINES
6.1 Anthelminthics
6.1.1 Intestinal anthelminthics
albendazole

Tablet(chewable):400mg.

levamisole

Tablet:50mg;150mg(ashydrochloride).

mebendazole

Tablet(chewable):100mg;500mg.

niclosamide*

Tablet(chewable):500mg.
Oralliquid:50mg(asembonate)/ml.

pyrantel
Tablet(chewable):250mg(asembonate).
ivermectin

Tablet(scored):3mg;6mg.

6.2 Antibacterials
6.2.1 Beta Lactam medicines
Capsuleortablet:250mg;500mg(anhydrous).
amoxicillin
Powderfororalliquid:125mg(anhydrous)/5ml.
amoxicillin+clavulanic
acid

Tablet:500mg+125mg.

ampicillin

Powderforinjection:500mg;1g(assodiumsalt)invial.

benzathine
benzylpenicillin

Powderforinjection:1.44gbenzylpenicillin(=2.4millionIU)
in5mlvial.

benzylpenicillin

Powderforinjection:600mg(=1millionIU);3g(=5
millionIU)(sodiumorpotassiumsalt)invial.
Powderforinjection:1g(assodiumsalt)invial.

cefazolin*
*Forsurgicalprophylaxis.
Capsule:400mg.
cefixime*

*Onlylistedforsingledosetreatmentofuncomplicated
anogenitalgonorrhoea.
Capsule:500mg;1g(assodiumsalt).

cloxacillin

Powderforinjection:500mg(assodiumsalt)invial.
Powderfororalliquid:125mg(assodiumsalt)/5ml.

Powderfororalliquid:250mg(aspotassiumsalt)/5ml.
phenoxymethylpenicillin
Tablet:250mg(aspotassiumsalt).
procainebenzylpenicillin

Powderforinjection:1g(=1millionIU);3g(=3millionIU)
invial.

ComplementaryList
ceftazidime

Powderforinjection:250mg(aspentahydrate)invial.

ceftriaxone

Powderforinjection:250mg,1g(assodiumsalt)invial.

imipenem*+
cilastatin*

Powderforinjection:250mg(asmonohydrate)+250mg(assodium
salt);500mg(asmonohydrate)+500mg(assodiumsalt)invial.
*Onlylistedforthetreatmentoflifethreateninghospitalbasedinfection
duetosuspectedorprovenmultidrugresistantinfection.

6.2.2 Other antibacterials

Capsule:250mgor500mg.
azithromycin*

Oralliquid:200mg/5ml.
*OnlylistedforsingledosetreatmentofgenitalChlamydia
trachomatisandoftrachoma.
Capsule:250mg.

chloramphenicol

Oilysuspensionforinjection:0.5g(assodium
succinate)/mlin2mlampoule.
Oralliquid:150mg(aspalmitate)/5ml.
Powderforinjection:1g(sodiumsuccinate)invial.

ciprofloxacin*

Tablet:250mg(ashydrochloride).
*Finalselectiondependsonindicationforuse.
Capsuleortablet:100mg(hydrochloride).

doxycycline*
*Finalselectiondependsonindicationforuse.
Capsuleortablet:250mg(asstearateorethylsuccinate).
erythromycin

Powderforinjection:500mg(aslactobionate)invial.
Powderfororalliquid:125mg/5ml(asstearateorethyl
succinate).

gentamicin*

Injection:10mg;40mg(assulfate)/mlin2mlvial.
*Finalselectiondependsonindicationforuse.

Injection:500mgin100mlvial.
metronidazole

Oralliquid:200mg(asbenzoate)/5ml.
Suppository:500mg;1g.
Tablet:200500mg.

nitrofurantoin

Tablet:100mg.

spectinomycin

Powderforinjection:2g(ashydrochloride)invial.
Injection:80mg+16mg/mlin5mland10mlampoules.

sulfamethoxazole+
trimethoprim

Oralliquid:200mg+40mg/5ml.
Tablet:100mg+20mg;400mg+80mg.

trimethoprim
nalidixicacid

Tablet:100mg;200mg.
500mgtablet,300mg/5mlsyrup.
5000,000IUtab,100,000IU/mldrops,100,000IUpessaries

ComplementaryList
Capsule:150mg.
clindamycin
Injection:150mg(asphosphate)/ml.
sulfadiazine

Injection:250mg(sodiumsalt)in4mlampoule.Tablet:500
mg.

vancomycin

Powderforinjection:250mg(ashydrochloride)
invial.

6.2.3 Antileprosy medicines

Medicinesusedinthetreatmentofleprosyshouldneverbeusedexceptincombination.
Combinationtherapyisessentialtopreventtheemergenceofdrugresistance.
clofazimine

Capsule:50mg;100mg.

dapsone

Tablet:25mg;50mg;100mg.

rifampicin

Capsuleortablet:150mg;300mg.

6.2.4 Antituberculosis medicines

ethambutol

Tablet:100400mg(hydrochloride).

Tablet:100300mg.
isoniazid
Tablet(scored):50mg.
Tablet:150mg+400mg.

isoniazid+ethambutol

Tablet:400mg.
Tablet(dispersible):150mg.

pyrazinamide

Tablet(scored):150mg.
Capsuleortablet:150mg;300mg.

rifampicin

Tablet:
60mg+30mg;150mg+75mg;300mg+
150mg.
rifampicin+isoniazid

60mg+60mg(Forintermittentusethree
timesweekly).
150mg+150mg(Forintermittentusethree
timesweekly).

rifampicin+isoniazid+ethambutol

Tablet:150mg+75mg+275mg.
Tablet:

60mg+30mg+150mg;150mg+75mg+
rifampicin+isoniazid+pyrazinamide 400mg.
150mg+150mg+500mg(Forintermittent
usethreetimesweekly).
rifampicin+isoniazid+pyrazinamide
+ethambutol

Tablet:150mg+75mg+400mg+275mg.

streptomycin

Powderforinjection:1g(assulfate)invial.

ComplementaryList
amikacin

Powderforinjection:1000mginvial.

paminosalicylic
acid

Granules:4ginsachet.

capreomycin

Powderforinjection:1000mginvial.

cycloserine

Capsuleortablet:250mg.

ethionamide

Tablet:125mg;250mg.

Tablet:500mg.

kanamycin

Powderforinjection:1000mginvial.
Tablet:200mg;400mg.

ofloxacin*

*Levofloxacinmaybeanalternativebasedonavailabilityand
programmeconsiderations.

6.3 Antifungal medicines

Vaginalcream:1%;10%.
clotrimazole
Vaginaltablet:100mg;500mg.
Capsule:50mg.
fluconazole

Injection:2mg/mlinvial.
Oralliquid:50mg/5ml.
Capsuleortablet:125mg;250mg.

griseofulvin

Lozenge:100000IU.
Pessary:100000IU.

nystatin

Tablet:100000IU;500000IU.
ComplementaryList
amphotericinB

Powderforinjection:50mginvial.
Capsule:250mg.

flucytosine
Infusion:2.5gin250ml.
potassiumiodide

Saturatedsolution.

6.4 Antiviral medicines

6.4.1 Antiherpes medicines
Powderforinjection:250mg(assodiumsalt)invial.

aciclovir

Tablet:200mg.
6.4.2 Antiretrovirals
6.4.2.1 Nucleoside/Nucleotide reverse transcriptase inhibitors
Oralliquid:100mg(assulfate)/5ml.
abacavir(ABC)
Tablet:300mg(assulfate).

Bufferedpowderfororalliquid:100mg;167mg;250mg
packets.
didanosine(ddI)

Capsule(unbufferedentericcoated):125mg;200mg;250mg;
400mg.
Tablet(bufferedchewable,dispersible):25mg;50mg;100mg;
150mg;200mg.
Capsule:200mg.
Oralliquid:10mg/ml.

emtricitabine(FTC)*

*FTCisanacceptablealternativeto3TC,basedonknowledge
ofthepharmacology,theresistancepatternsandclinicaltrialsof
antiretrovirals.
Oralliquid:50mg/5ml.

lamivudine(3TC)
Tablet:150mg.
Capsule:15mg;20mg;30mg;40mg.*
stavudine(d4T)

*TheCommitteeexpectsthisdosageformtobereviewedfor
possibledeletionatthenextmeeting.
Powderfororalliquid:5mg/5ml.

tenofovirdisoproxil
fumarate(TDF)

Tablet:300mg(tenofovirdisoproxilfumarateequivalentto245
mgtenofovirdisoproxil).
Capsule:100mg;250mg.

zidovudine(ZDVor
AZT)

Oralliquid:50mg/5ml.
SolutionforIVinfusioninjection:10mg/mlin20mlvial.
Tablet:300mg.

6.4.2.2 Non-nucleoside reverse transcriptase inhibitors

Capsule:50mg;100mg;200mg.
efavirenz(EFVor
EFZ)

Oralliquid:150mg/5ml.
Tablet:600mg.
Oralliquid:50mg/5ml.

nevirapine(NVP)
Tablet:200mg.
6.4.2.3 Protease inhibitors
Ritonavirisrecommendedforuseincombinationasapharmacologicalbooster,andnot
asanantiretroviralinitsownright.

indinavir(IDV)

Capsule:200mg;333mg;400mg(assulfate).

lopinavir+ritonavir
(LPV/r)

Capsule:133.3mg+33.3mg.
Oralliquid:400mg+100mg/5ml.
Oralpowder:50mg/g.

nelfinavir(NFV)
Tablet:250mg(asmesilate).
Oralliquid:400mg/5ml.
ritonavir
Oralsoliddosageform:100mg.
saquinavir(SQV)

Capsule:200mg.

FIXED-DOSE COMBINATIONS
efavirenz+
emtricitabine*+
tenofovir

emtricitabine*+
tenofovir

Tablet:600mg+200mg+300mg.
*FTCisanacceptablealternativeto3TC,basedonknowledge
ofthepharmacology,theresistancepatternsandclinicaltrials
ofantiretrovirals.
Tablet:200mg+300mg.
*FTCisanacceptablealternativeto3TC,basedonknowledge
ofthepharmacology,theresistancepatternsandclinicaltrials
ofantiretrovirals.

stavudine+lamivudine
+nevirapine

Tablet:30mg+150mg+200mg.

zidovudine+
lamivudine

Tablet:300mg+150mg.

zidovudine+
lamivudine+
nevirapine

Tablet:300mg+150mg+200mg.

6.4.3 Other antivirals

ribavirin

Injectionforintravenousadministration:1000mgand800mg
in10mlphosphatebuffersolution.
Oralsoliddosageforms:200mg;400mg;600mg.

6.5 Antiprotozoal medicines

6.5.1 Antiamoebic and antigiardiasis medicines
diloxanide

Tablet:500mg(furoate).

Injection:500mgin100mlvial.
metronidazole

Oralliquid:200mg(asbenzoate)/5ml.
Tablet:200500mg.

6.5.2 Antileishmaniasis medicines

sodiumstibogluconate
(S)

100mginj.

ComplementaryList
amphotericinB

Powderforinjection:50mginvial.

6.5.3 Antimalarial medicines

6.5.3.1 For curative treatment
MedicinesforthetreatmentofP.falciparummalariacasesshouldbeusedincombination.
Tablet:153mgor200mg(ashydrochloride).
amodiaquine*

*Tobeused(a)incombinationwithartesunate50mgOR(b)
maybeusedaloneforthetreatmentofP.vivax,P.ovaleand
P.malariaeinfections.
Oilyinjection:80mg/mlin1mlampoule.

artemether
Foruseinthemanagementofseveremalaria.
Tablet:20mg+120mg.
artemether+
lumefantrine*

artesunate*

*Notrecommendedinthefirsttrimesterofpregnancyorin
childrenbelow5kg.
Injection:ampoules,containing60mganhydrousartesunicacid
withaseparateampouleof5%sodiumbicarbonatesolution.
Foruseinthemanagementofseveremalaria.

Tablet:50mg.
*Tobeusedincombinationwitheitheramodiaquine,
mefloquineorsulfadoxine+pyrimethamine.
Oralliquid:50mg(asphosphateorsulfate)/5ml.

chloroquine*

Tablet:100mg;150mg(asphosphateorsulfate).
*ForuseonlyforthetreatmentofP.vivaxinfection.

Capsule:100mg(ashydrochloride).
doxycycline*

Tablet(dispersible):100mg(asmonohydrate).
*Foruseonlyincombinationwithquinine.
Tablet:250mg(ashydrochloride).

mefloquine*
*Tobeusedincombinationwithartesunate50mg.
Tablet:7.5mg;15mg(asdiphosphate)
primaquine*

*OnlyforusetoachieveradicalcureofP.vivaxandP.ovale
infections,givenfor14days.
Injection:300mgquininehydrochloride/mlin2mlampoule.

quinine*

Tablet:300mg(quininesulfate)or300mg(quininebisulfate).
*Foruseonlyinthemanagementofseveremalaria,andshould
beusedincombinationwithdoxycycline.

sulfadoxine+
pyrimethamine*

Tablet:500mg+25mg.
*Onlyincombinationwithartesunate50mg.

6.5.3.2 For prophylaxis

Oralliquid:50mg(asphosphateorsulfate)/5ml.
chloroquine*

Tablet:150mg(asphosphateorsulfate).
*ForuseonlyincentralAmericanregions,forusefor
P.vivax.

doxycycline

Capsuleortablet:100mg(hydrochloride).

mefloquine

Tablet:250mg(ashydrochloride).
Tablet:100mg(hydrochloride).

proguanil*
*Foruseonlyincombinationwithchloroquine.
6.5.4 Antipneumocystosis and antitoxoplasmosis medicines
pyrimethamine

Tablet:25mg.

sulfamethoxazole+
trimethoprim

Injection:80mg+16mg/mlin5mlampoule;80mg+
16mg/mlin10mlampoule.

7. ANTIMIGRAINE MEDICINES
7.1 For treatment of acute attack
acetylsalicylicacid

Tablet:300500mg.

paracetamol

Tablet:300500mg.

7.2 For prophylaxis

propranolol

Tablet:20mg;40mg(hydrochloride).

8. ANTINEOPLASTIC, IMMUNOSUPPRESSIVES
8.1 Immunosuppressive medicines
ComplementaryList
Powderforinjection:100mg(assodiumsalt)invial.
azathioprine
Tablet:50mg.
Capsule:25mg.
ciclosporin

Concentrateforinjection:50mg/mlin1mlampoulefor
organtransplantation.

8.2 Cytotoxic medicines

ComplementaryList
asparaginase

Powderforinjection:10000IUinvial.

bleomycin

Powderforinjection:15mg(assulfate)invial.
Injection:3mg/mlin10mlampoule.

calciumfolinate
Tablet:15mg.
chlorambucil

Tablet:2mg.

cisplatin

Powderforinjection:10mg;50mginvial.
Powderforinjection:500mginvial.

cyclophosphamide
Tablet:25mg.
cytarabine

Powderforinjection:100mginvial.

dacarbazine

Powderforinjection:100mginvial.

dactinomycin

Powderforinjection:500microgramsinvial.

daunorubicin

Powderforinjection:50mg(ashydrochloride)invial.

doxorubicin

Powderforinjection:10mg;50mg(hydrochloride)invial.
Capsule:100mg.

etoposide
Injection:20mg/mlin5mlampoule.
fluorouracil

Injection:50mg/mlin5mlampoule.

mercaptopurine

Tablet:50mg.
Powderforinjection:50mg(assodiumsalt)invial.

methotrexate
Tablet:2.5mg(assodiumsalt).
procarbazine

Capsule:50mg(ashydrochloride).

vinblastine

Powderforinjection:10mg(sulfate)invial.

vincristine

Powderforinjection:1mg;5mg(sulfate)invial.

8.3 Hormones and antihormones

ComplementaryList
dexamethasone

Injection:4mgdexamethasonephosphate(asdisodiumsalt)in1ml
ampoule.

hydrocortisone

Powderforinjection:100mg(assodiumsuccinate)invial.
Tablet:5mg;25mg.

prednisolone*

*Thereisnoevidenceforcompleteclinicalsimilaritybetween
prednisoloneanddexamethasoneathighdoses.

tamoxifen

Tablet:10mg;20mg(ascitrate).

9. ANTIPARKINSONISM MEDICINES
procyclidine(S),(T)

5mg.tab.

levodopa+

Tablet:100mg+10mg;250mg+25mg.

10. MEDICINES AFFECTING THE BLOOD

10.1 Antianaemia medicines
Oralliquid:equivalentto25mgiron(assulfate)/ml.
ferroussalt
Tablet:equivalentto60mgiron.
ferroussalt+folic
acid

Tabletequivalentto60mgiron+400microgramsfolicacid
(Nutritionalsupplementforuseduringpregnancy).

folicacid

Tablet:1mg;5mg.

hydroxocobalamin

Injection:1mgin1mlampoule.

10.2 Medicines affecting coagulation

heparinsodium

Injection:1000IU/ml;5000IU/ml;20,000
IU/mlin1mlampoule.
Injection:10mg/mlin5mlampoule.

phytomenadione
Tablet:10mg.
protaminesulfate

Injection:10mg/mlin5mlampoule.
Tablet:1mg;2mg;5mg(sodiumsalt).

warfarin

11. BLOOD PRODUCTS AND PLASMA SUBSTITUTES

11.1 Plasma substitutes
Injectablesolution:6%.
dextran70*

*Polygeline,injectablesolution,3.5%is
consideredasequivalent.

11.2 Plasma fractions for specific use

AllplasmafractionsshouldcomplywiththeWHORequirementsfortheCollection,
ProcessingandQualityControlofBlood,BloodComponentsandPlasmaDerivatives.
ComplementaryList

humannormalimmunoglobulin

Intramuscularadministration:16%protein
solution.
Intravenousadministration:5%,10%protein
solution.

factorVIIIconcentrate

Dried.

factorIXcomplex(coagulation

factors,II,VII,IX,X)concentrate

Dried.

12. CARDIOVASCULAR MEDICINES

12.1 Antianginal medicines
atenolol

Tablet:50mg;100mg.

glyceryltrinitrate

Tablet(sublingual):500micrograms.

isosorbidedinitrate

Tablet(sublingual):5mg.

verapamil

Tablet:40mg;80mg(hydrochloride).

12.2 Antiarrhythmic medicines

ThissubsectionwillbereviewedatthenextmeetingoftheExpertCommittee.
atenolol

Tablet:50mg;100mg.
Injection:250micrograms/mlin2mlampoule.

digoxin

Oralliquid:50micrograms/ml.
Tablet:62.5micrograms;250micrograms.

epinephrine(adrenaline)

Injection:100micrograms/ml(asacidtartrate
orhydrochloride)in10mlampoule.

lidocaine

Injection:20mg(hydrochloride)/mlin5ml
ampoule.
Injection:2.5mg(hydrochloride)/mlin2mlampoule.

verapamil
Tablet:40mg;80mg(hydrochloride).
ComplementaryList
procainamide

Injection:100mg(hydrochloride)/mlin10mlampoule.

quinidine

Tablet:200mg(sulfate).

12.3 Antihypertensive medicines

amlodipine

Tablet:5mg.

atenolol

Tablet:50mg;100mg.

enalapril

Tablet:2.5mg.
Powderforinjection:20mg(hydrochloride)inampoule.
Tablet:25mg,50mg(hydrochloride).

hydralazine*

hydrochlorothiazide

*Hydralazineislistedforuseintheacutemanagementofsevere
pregnancyinducedhypertensiononly.Itsuseinthetreatmentof
essentialhypertensionisnotrecommendedinviewofthe
availabilityofmoreevidenceofefficacyandsafetyofother
medicines.
Tablet(scored):25mg.

Tablet:250mg.

methyldopa*

*Methyldopaislistedforuseinthemanagementof
pregnancyinducedhypertensiononly.Itsuseinthetreatmentof
essentialhypertensionisnotrecommendedinviewofthe
availabilityofmoreevidenceofefficacyandsafetyofother
medicines.

ComplementaryList
sodium
nitroprusside

Powderforinfusion:50mginampoule.

12.4 Medicines used in heart failure

ThissubsectionwillbereviewedatthenextmeetingoftheExpertCommittee.
Injection:250micrograms/mlin2mlampoule.
digoxin

Oralliquid:50micrograms/ml.
Tablet:62.5micrograms;250micrograms.

enalapril
furosemide

Tablet:2.5mg.
Injection:10mg/mlin2mlampoule.
Tablet:40mg.

hydrochlorothiazide

Tablet(scored):25mg.

ComplementaryList
dopamine

Injection:40mg/ml(hydrochloride)in5mlvial.

dobutamine(T)

250mginj.

12.5 Antithrombotic medicines

acetylsalicylicacid

Tablet:100mg.

ComplementaryList
streptokinase

Powderforinjection:1.5millionIUinvial.

12.6 Lipid-lowering agents

simvastatin*

Tablet:5mg;10mg;20mg;40mg.
*Foruseinhighriskpatients.

13. DERMATOLOGICAL MEDICINES (topical)

13.1 Antifungal medicines
benzoicacid+salicylicacid

Ointmentorcream:6%+3%.

miconazole

Ointmentorcream:2%(nitrate).

sodiumthiosulfate

Solution:15%.

ComplementaryList
seleniumsulfide

Detergentbasedsuspension:2%.

13.2 Anti-infective medicines

methylrosaniliniumchloride(gentian

Aqueoussolution:0.5%.

violet)

Tincture:0.5%.

neomycinsulfate+bacitracin

Ointment:5mgneomycinsulfate+250IU
bacitracinzinc/g.

potassiumpermanganate

Aqueoussolution:1:10000.

Cream:1%,in500gcontainer.

silversulfadiazine

13.3 Anti-inflammatory and antipruritic medicines

betamethasone

Ointmentorcream:0.1%(asvalerate).

calaminelotion

Lotion.

hydrocortisone

Ointmentorcream:1%(acetate).

13.4 Astringent medicines

Solution:5%.

aluminiumdiacetate

13.5 Medicines affecting skin differentiation and proliferation

benzoylperoxide

Lotionorcream:5%.

coaltar

Solution:5%.

dithranol

Ointment:0.1%2%.

fluorouracil

Ointment:5%.

podophyllumresin

Solution:1025%.

salicylicacid

Solution:5%.

urea

Ointmentorcream:10%.

13.6 Scabicides and pediculicides

benzylbenzoate

Lotion:25%.

Cream:5%.
permethrin
Lotion:1%.

14. DIAGNOSTIC AGENTS

14.1 Ophthalmic medicines
fluorescein

Eyedrops:1%(sodiumsalt).

tropicamide

Eyedrops:0.5%.

14.2 Radiocontrast media

amidotrizoate

Injection:140420mgiodine(assodiumormegluminesalt)/ml
in20mlampoule.

bariumsulfate

Aqueoussuspension.

iohexol

Injection:140350mgiodine/mlin5ml;10ml;20ml
ampoules.

ComplementaryList
meglumine
iotroxate

Solution:58giodinein100250ml.

15. DISINFECTANTS AND ANTISEPTICS

15.1 Antiseptics
chlorhexidine

Solution:5%(digluconate)fordilution.

ethanol

Solution:70%(denatured).

polyvidoneiodine

Solution:10%.

15.2 Disinfectants
chlorinebase
compound

Powder:(0.1%availablechlorine)forsolution.

chloroxylenol

Solution:4.8%.

glutaral

Solution:2%.

16. DIURETICS
amiloride
furosemide

Tablet:5mg(hydrochloride).
Injection:10mg/mlin2mlampoule.
Tablet:40mg.

hydrochlorothiazide

Tablet(scored):25mg.

mannitol

Injectablesolution:10%;20%.

spironolactone

Tablet:25mg.

17. GASTROINTESTINAL MEDICINES

17.1 Antacids and other antiulcer medicines
aluminium
hydroxide

Oralliquid:320mg/5ml.
Tablet:500mg.
Injection:25mg/mlin2mlampoule.

ranitidine

Oralliquid:75mg/5ml.
Tablet:150mg(ashydrochloride).

magnesium
hydroxide

Oralliquid:equivalentto550mgmagnesiumoxide/10ml.

Lactulose

3.5mg/5mlsyrup

Omeprazole

20mgcap.

17.2 Antiemetic medicines

Injection:5mg(hydrochloride)/mlin2mlampoule.
metoclopramide
Tablet:10mg(hydrochloride).
Injection:25mg(hydrochloride)/mlin2mlampoule.
promethazine

Oralliquid:5mg(hydrochloride)/5ml.
Tablet:10mg;25mg(hydrochloride).

17.3 Anti-inflammatory medicines

Retentionenema.
sulfasalazine

Suppository:500mg.
Tablet:500mg.

ComplementaryList
hydrocortisone

Retentionenema.
Suppository:25mg(acetate).(theonlyappliestohydrocortisone
retentionenema).

17.4 Laxatives
senna

Tablet:7.5mg(sennosides)(ortraditionaldosageforms).

17.5 Medicines used in diarrhoea

17.5.1 Oral rehydration

glucose:75mEqsodium:75mEqormmol/lchloride:65
mEqormmol/lpotassium:20mEqormmol/lcitrate:10
mmol/losmolarity:245mOsm/lglucose:13.5g/lsodium
chloride:2.6g/lpotassiumchloride:1.5g/ltrisodiumcitrate
dihydrate+:2.9g/l
oralrehydration
salts*

+trisodiumcitratedihydratemaybereplacedbysodiumhydrogen
carbonate(sodiumbicarbonate)2.5g/l.However,asthestability
ofthislatterformulationisverypoorundertropicalconditions,it
isonlyrecommendedwhenmanufacturedforimmediateuse.
*Incasesofcholeraahigherconcentrationofsodiummaybe
required.

17.5.2 Medicines for diarrhoea in children

Oralliquid:in10mgperunitdosageforms.
zincsulfate*

Tablet:in10mgperunitdosageforms.
*Inacutediarrhoeazincsulfateshouldbeusedasanadjunctto
oralrehydrationsalts.

17.5.3 Antidiarrhoeal (symptomatic) medicines in adults

Tablet:30mg(phosphate).
codeine*

18. HORMONES, OTHER ENDOCRINE MEDICINES AND

CONTRACEPTIVES
18.1 Adrenal hormones and synthetic substitutes
Addisonsdiseaseisararecondition;adrenalhormonesarealreadyincludedinsection
3.
18.1 Androgens
ComplementaryList
testosterone

Injection:200mg(enantate)in1mlampoule.

18.2 Contraceptives
18.2.1 Oral hormonal contraceptives
ethinylestradiol+
levonorgestrel

Tablet:30micrograms+150micrograms.

ethinylestradiol+
norethisterone

Tablet:35micrograms+1.0mg.

levonorgestrel

Tablet:30micrograms;750micrograms(packoftwo);1.5mg.

18.2.2 Injectable hormonal contraceptives

medroxyprogesteroneacetate
Depotinjection:150mg/mlin1mlvial.

medroxyprogesteroneacetate
Injection:25mg+5mg.
+estradiolcypionate
norethisteroneenantate

Oilysolution:200mg/mlin1mlampoule.

18.2.3 Intrauterine devices

coppercontainingdevice

18.2.4 Barrier methods

condoms

diaphragms

18.2.5 Implantable contraceptives

levonorgestrelreleasing
implant

Tworodlevonorgestrelreleasingimplant,eachrod
containing75mgoflevonorgestrel(150mgtotal).

18.3 Estrogens
Tablet:10micrograms;50micrograms.
ethinylestradiol*

*Thepublichealthrelevanceand/orcomparativeefficacy
and/orsafetyofthisitemhasbeenquestionedandits
continuedinclusiononthelistwillbereviewedatthe
nextmeetingofthexpertCommittee.

18.4 Insulins and other antidiabetic agents

glibenclamide

Tablet:2.5mg;5mg.

insulininjection(soluble)

Injection:100IU/mlin10mlvial.

intermediateactinginsulin

Injection:40IU/mlin10mlvial;100IU/mlin10mlvial
(ascompoundinsulinzincsuspensionorisophane
insulin).
Tablet:500mg(hydrochloride).

metformin

18.5 Ovulation inducers

ComplementaryList
clomifene

Tablet:50mg(citrate).

18.6 Progestogens
Tablet:5mg.
norethisterone*

*Thepublichealthrelevanceand/orcomparativeefficacy
and/orsafetyofthisitemhasbeenquestionedandits
continuedinclusiononthelistwillbereviewedatthe
nextmeetingofthexpertCommittee.

ComplementaryList
Tablet:5mg.
medroxyprogesterone
acetate*

*Thepublichealthrelevanceand/orcomparativeefficacy
and/orsafetyofthisitemhasbeenquestionedandits
continuedinclusiononthelistwillbereviewedatthe
nextmeetingofthexpertCommittee.

18.7 Thyroid hormones and antithyroid medicines

levothyroxine

Tablet:50micrograms;100micrograms(sodiumsalt).

potassiumiodide

Tablet:60mg.

propylthiouracil

Tablet:50mg.

19. IMMUNOLOGICALS
19.1 Diagnostic agents
tuberculin,purifiedprotein
derivative(PPD)

Injection.

19.2 Sera and immunoglobulins

AllplasmafractionsshouldcomplywiththeWHORequirementsfortheCollection,
ProcessingandQualityControlofBlood,BloodComponentsandPlasmaDerivatives.
antiDimmunoglobulin
(human)

Injection:250microgramsinsingledosevial.

antitetanusimmunoglobulin
(human)

Injection:500IUinvial.
Injection.

antivenomimmunoglobulin*
*Exacttypetobedefinedlocally.
diphtheriaantitoxin

Injection:10000IU;20000IUinvial.

rabiesimmunoglobulin

Injection:150IU/mlinvial.

AntihepatitisB

injectin.

immunoglobulin
19.3 Vaccines
Vaccine for Universal Immunization
BCG(dried)vaccine

inj

diptheriapertussistetanus

inj.

vaccine
dipatheriatetanusvaccine

inj.

measlesmumpsrubella

vaccine

inj.

measlesvaccine

inj.

poliomyelitisvaccine

oralsolution,liveattenuated

tetanusvaccine

inj.

Haemophilus influenzae
type B vaccine

inj.

Rota virus vaccine

inj.

Typhoid Vaccines

inj.

VaccinesforSpecificUse.

Hepatitis A vaccine

inj

hepatitisBvaccine

inj.

meningococcalvaccine

inj.

rabiesvaccine

inj.

rubellavaccine

inj

Cholera Vaccines

inj

Flu vaccine (influenza)

inj

Pneumococcal vaccine

inj

20. MUSCLE RELAXANTS (PERIPHERALLY-ACTING) AND

CHOLINESTERASE INHIBITORS
alcuronium

neostigmine

Injection:5mg(chloride)/mlin2mlampoule.
Injection:500microgramsin1mlampoule;2.5mg(metilsulfate)
in1mlampoule.
Tablet:15mg(bromide).
Injection:50mg(chloride)/mlin2mlampoule.

suxamethonium
Powderforinjection(chloride)invial.
ComplementaryList
Injection:1mgin1mlampoule.
pyridostigmine
Tablet:60mg(bromide).
vecuronium

Powderforinjection:10mg(bromide)invial.

21. OPHTHALMOLOGICAL PREPARATIONS

ThissectionwillbereviewedatthenextmeetingoftheExpertCommittee.
21.1 Anti-infective agents
aciclovir
gentamicin*

Ointment:3%W/W.
Solution(eyedrops):0.3%(sulfate).
*Finalselectiondependsonindicationforuse.

tetracycline

Eyeointment:1%(hydrochloride).

21.2 Anti-inflammatory agents

prednisolone

Solution(eyedrops):0.5%(sodiumphosphate).

21.3 Local anaesthetics

tetracaine

Solution(eyedrops):0.5%(hydrochloride).

21.4 Miotics and antiglaucoma medicines

acetazolamide

Tablet:250mg.

pilocarpine

Solution(eyedrops):2%;4%(hydrochlorideornitrate).

timolol

Solution(eyedrops):0.25%;0.5%(asmaleate).

21.5 Mydriatics
atropine
ComplementaryList

Solution(eyedrops):0.1%;0.5%,1%(sulfate).

epinephrine(adrenaline) Solution(eyedrops):2%(ashydrochloride).

22. OXYTOCICS AND ANTIOXYTOCICS

22.1 Oxytocics
ergometrine

Injection:200micrograms(hydrogenmaleate)in1ml
ampoule.

oxytocin

Injection:10IUin1mlampoule.

22.2 Antioxytocics (tocolytics)

nifedipine

Immediatereleasecapsule:10mg.

23. PERITONEAL DIALYSIS SOLUTION

ComplementaryList
intraperitonealdialysis
solution(ofappropriate

Parenteralsolution.

composition)

24. PSYCHOTHERAPEUTIC MEDICINES

24.1 Medicines used in psychotic disorders
Injection:25mg(hydrochloride)/mlin2mlampoule.
chlorpromazine

Oralliquid:25mg(hydrochloride)/5ml.
Tablet:100mg(hydrochloride).

fluphenazine

Injection:25mg(decanoateorenantate)in1ml
ampoule.
Injection:5mgin1mlampoule.

haloperidol

Tablet:2mg;5mg.

24.2 Medicines used in mood disorders

24.2.1 Medicines used in depressive disorders
amitriptyline

Tablet:25mg(hydrochloride).

fluoxetine

Capsuleortablet:20mg(presentashydrochloride).

24.2.2 Medicines used in bipolar disorders

carbamazepine

Tablet(scored):100mg;200mg.

lithiumcarbonate

Capsuleortablet:300mg.

valproicacid

Tablet(entericcoated):200mg;500mg(sodium
valproate).

Risperidone

1mg,2mg,3mgtab.

24.3 Medicines used in generalized anxiety and sleep disorders

diazepam

Tablet(scored):2mg;5mg.

24.4 Medicines used for obsessive compulsive disorders and panic attacks
clomipramine

Capsule:10mg;25mg(hydrochloride).

24.5 Medicines used in substance dependence programmes

ComplementaryList
Concentratefororalliquid:5mg/ml;10mg/ml
(hydrochloride).
methadone*

Oralliquid:5mg/5ml;10mg/5ml.
*Thesquareboxisaddedtoincludebuprenorphine.The
medicinesshouldonlybeusedwithinanestablished
supportprogramme.

25. MEDICINES ACTING ON THE RESPIRATORY TRACT

25.1 Antiasthmatic and medicines for chronic obstructive pulmonary
disease
beclometasone

Inhalation(aerosol):50microgramsperdose
(dipropionate);250micrograms(dipropionate)per
dose.

epinephrine(adrenaline)

Injection:1mg(ashydrochlorideorhydrogen
tartrate)in1mlampoule.

ipratropiumbromide

Inhalation(aerosol):20micrograms/metereddose.
Inhalation (aerosol): 100 micrograms (as sulfate) per
dose.
Injection: 50 micrograms (as sulfate)/ml in 5ml
ampoule.

salbutamol

Oralliquid:2mg/5ml.
Respirator solution for use in nebulizers: 5 mg (as
sulfate)/ml.
Tablet:2mg;4mg(assulfate).

25.2 Other medicines acting on the respiratory tract

aminophylline

100 & 200 mg tab. 250 mg inj.

theophylline

180 & 270 mg tab. 350 mg tab.

(S.R) 120 mg/5ml syrup.

26. SOLUTIONS CORRECTING WATER, ELECTROLYTE AND ACIDBASE DISTURBANCES

26.1 Oral
oralrehydrationsalts

Seesection17.5.1.

potassiumchloride

Powderforsolution.

26.2 Parenteral
glucose

Injectablesolution:5%;10%isotonic;50%hypertonic.

glucosewithsodium

Injectablesolution:4%glucose,0.18%sodiumchloride

chloride

(equivalenttoNa 30mmol/l,Cl30mmol/l).

potassiumchloride

Solution:11.2%in20mlampoule(equivalenttoK 1.5

mmol/ml,Cl 1.5mmol/ml).
+

sodiumchloride

Injectablesolution:0.9%isotonic(equivalenttoNa 154
mmol/l,Cl154mmol/l.
+

sodiumhydrogen
carbonate

sodiumlactate,
compoundsolution

Injectablesolution:1.4%isotonic(equivalenttoNa 167
mmol/l,HCO3167mmol/l).
+

Solution:8.4%in10mlampoule(equivalenttoNa 1000
mmol/l,HCO31000mmol/l).
Injectablesolution.

26.3 Miscellaneous
2ml;5ml;10mlampoules.
waterforinjection

27. VITAMINS AND MINERALS

ascorbicacid
ergocalciferol

Tablet:50mg.
Capsuleortablet:1.25mg(50000IU).
Oralliquid:250micrograms/ml(10000IU/ml).

Capsule:200mg.
iodine

Iodizedoil:1ml(480mgiodine);0.5ml(240mgiodine)in
ampoule(oralorinjectable);0.57ml(308mgiodine)in
dispenserbottle.

nicotinamide

Tablet:50mg.

pyridoxine

Tablet:25mg(hydrochloride).
Capsule:50000IU;100000IU;200000IU(aspalmitate).
Oraloilysolution:100000IU(aspalmitate)/mlinmultidose
dispenser.

retinol
Tablet(sugarcoated):10000IU(aspalmitate).
Watermiscibleinjection:100000IU(aspalmitate)in2ml
ampoule.
riboflavin

Tablet:5mg.

sodiumfluoride

Inanyappropriatetopicalformulation.

thiamine

Tablet:50mg(hydrochloride).

ComplementaryList

calciumgluconate

Injection:100mg/mlin10mlampoule.

INDEX

Abacavir(ABC)..........................................................
Acetazolamide..........................................................
Acetylcysteine............................................................
Acetylsalicylicacid.................................................
Aciclovir....................................................................
Albendazole................................................................
Alcuronium...............................................................
Allopurinol.................................................................
Aluminiumdiacetate...............................................
Aluminiumhydroxide............................................
Amidotrizoate..........................................................
Amikacin......................................................................
Amiloride..................................................................
Aminophylline
Amitriptyline............................................................
Amlodipine...............................................................
Amodiaquine............................................................
Amoxicillin.................................................................
Amoxicillin+clavulanicacid..................................
AmphotericinB............................................................
Ampicillin...................................................................
AntiDimmunoglobulin(human).........................
AntiHepatitisBImmunoglobulin..
Antitetanusimmunoglobulin(human).................
Antivenomimmunoglobulin.................................
Artemether................................................................
Artemether+lumefantrine.....................................
Artesunate.................................................................
Ascorbicacid............................................................
Asparaginase...............................................................
Atenolol......................................................................
Atropine......................................................................
Azathioprine................................................................
Azithromycin..............................................................
Bacitracin..................................................................
Bariumsulfate.........................................................
BCG(dried)vaccine.
Beclometasone.........................................................
Benzathinebenzylpenicillin....................................
Benznidazole............................................................
Benzoicacid.............................................................
Benzoicacid+salicylicacid...................................
Benzoylperoxide.....................................................
Benzylbenzoate.......................................................

Benzylpenicillin.........................................................
Betamethasone.........................................................
Bleomycin...................................................................
Bupivacaine................................................................
Calaminelotion........................................................
Calciumfolinate..........................................................
Calciumgluconate....................................................
Capreomycin.................................................................
Carbamazepine..........................................................
Carbidopa..................................................................
Cefazolin......................................................................
Cefixime.......................................................................
Ceftazidime...................................................................
Ceftriaxone....................................................................
Charcoal,activated.....................................................
Chlorambucil..................................................................
Chloramphenicol........................................................
Chlorhexidine.............................................................
Chlorinebasecompound........................................
Chloroquine...................................................................
Chloroxylenol...........................................................
Chlorphenamine.........................................................
Chlorpromazine.......................................................
CholeraVaccine
Ciclosporin.................................................................
Cilastatin......................................................................
Ciprofloxacin..............................................................
Cisplatin......................................................................
Clavulanicacid...........................................................
Clindamycin.................................................................
Clofazimine.................................................................
Clomifene....................................................................
Clomipramine...........................................................
Clotrimazole...............................................................
Cloxacillin...................................................................
Coaltar......................................................................
Codeine.......................................................................
Condoms...................................................................
Coppercontainingdevice.......................................
Cyclophosphamide......................................................
Cycloserine....................................................................
Cytarabine...................................................................
Dacarbazine................................................................
Dactinomycin..............................................................
Dapsone......................................................................
Daunorubicin..............................................................
Deferoxamine.............................................................

Dexamethasone.........................................................
Dextran70.................................................................
Diaphragms..............................................................
Diazepam...................................................................
Didanosine(ddi)........................................................
Digoxin..........................................................................
Diloxanide.................................................................
Dimercaprol................................................................
Diphtheriaantitoxin................................................
Diptheriapertussistetanusvaccine
Dipatheriatetanusvaccine.
Dithranol...................................................................
DLmethionine..........................................................
Dobutamine..
Dopamine....................................................................
Doxorubicin................................................................
Doxycycline.................................................................
Efavirenz..........................................................................
Efavirenz+emtricitabine+tenofovir...................
Eflornithine..............................................................
Emtricitabine........................................................
Emtricitabine+tenofovir........................................
Enalapril...................................................................
Ephedrine......................................................................
Epinephrine(adrenaline)........................................
Ergocalciferol...........................................................
Ergometrine..............................................................
Erythromycin.............................................................
Estradiolcypionate..................................................
Ethambutol................................................................
Ethanol......................................................................
Ethinylestradiol............................................................
Ethinylestradiol+levonorgestrel..........................
Ethinylestradiol+norethisterone..........................
Ethionamide..................................................................
Ethosuximide................................................................
Etoposide....................................................................
FactorIXcomplex(coagulationfactors,II,VII,IX,X)oncentrate........
FactorVIIIconcentrate...............................................
Ferroussalt...............................................................
Ferroussalt+folicacid...........................................
Fluconazole.................................................................
Flucytosine....................................................................
Fluorescein................................................................
Fluorouracil..................................................................
Fluoxetine.................................................................
Fluphenazine............................................................

Fluvaccine(influenza)
Folicacid......................................................................
Furosemide...................................................................
Gentamicin...................................................................
Gentianviolet...........................................................
Glibenclamide..........................................................
Glucose......................................................................
Glutaral......................................................................
Glyceryltrinitrate.....................................................
Griseofulvin.................................................................
HaemophilusinfluenzaetypeBvaccine..
Haloperidol................................................................
Halothane.....................................................................
HepatitisAvaccine
HepatitisBvaccine.
Heparinsodium........................................................
Humannormalimmunoglobulin................................
Hydralazine..............................................................
Hydrochlorothiazide....................................................
Hydrocortisone.................................................................
Hydroxocobalamin..................................................
Ibuprofen....................................................................
Imipenem+cilastatin...................................................
Immunoglobulin..............................................................
Indinavir(IDV).....................................................................
Insulininjection(soluble)................................................
Intermediateactinginsulin..............................................
Intraperitonealdialysissolution(ofappropriatecomposition)..........................................................
Iodine..................................................................
Iohexol......................................................................
Ipratropiumbromide..............................................
Isoniazid.....................................................................
Isoniazid+ethambutol.............................................
Isosorbidedinitrate.................................................
Ivermectin..................................................................
Kanamycin....................................................................
Ketamine.....................................................................
Lactulose
Lamivudine.................................................................
Lamivudine(3TC)......................................................
Levamisole.................................................................
Levodopa...................................................................
Levodopa+carbidopa.............................................
Levonorgestrel............................................................
Levonorgestrelreleasingimplant..........................
Levothyroxine...........................................................
Lidocaine...............................................................

Lidocaine+epinephrine(adrenaline)......................
Lithiumcarbonate....................................................
Lopinavir...................................................................
Lopinavir+ritonavir(LPV/r)..................................
Lumefantrine............................................................
Magnesiumhydroxide...........................................
Magnesiumsulfate....................................................
Mannitol...................................................................
Measlesmumpsrubellavaccine..
Measlesvaccine.
Mebendazole..............................................................
Medroxyprogesteroneacetate.........................
Medroxyprogesteroneacetate+estradiolcypionate.............................................................
Mefloquine..............................................................
Meglumineiotroxate..................................................
Melarsoprol..............................................................
Meningococcalvaccine.
Mercaptopurine..........................................................
Metformin................................................................
Methadone..................................................................
Methotrexate...............................................................
Methyldopa..............................................................
Methyleneblue..........................................................
Methylrosaniliniumchloride(gentianviolet)............
Methylthioniniumchloride(methyleneblue)............
Metoclopramide......................................................
Metronidazole.........................................................
Miconazole...............................................................
Morphine...................................................................
Nalidixicacid..
Naloxone.....................................................................
Nelfinavir(NFV)......................................................
Neomycinsulfate.....................................................
Neomycinsulfate+bacitracin................................
Neostigmine.............................................................
Nevirapine................................................................
Niclosamide................................................................
Nicotinamide............................................................
Nifedipine.................................................................
Nifurtimox................................................................
Nitrofurantoin............................................................
Nitrousoxide..............................................................
Norethisterone.............................................................
Nystatin.........................................................................
Ofloxacin..........................................................................
Omeprazole
Oralrehydrationsalts............................................

Oxygen........................................................................
Oxytocin....................................................................
Paminosalicylicacid...................................................
Paracetamol................................................................
Penicillamine................................................................
Permethrin...............................................................
Pethidine
Phenobarbital............................................................
Phenoxymethylpenicillin.........................................
Phenytoin...................................................................
Phytomenadione.....................................................
Pilocarpine...............................................................
Pneumococcalvaccine.
Podophyllumresin.................................................
Poliomyelitisvaccineoralsolution(liveattenuated).
Polyvidoneiodine...................................................
Potassiumchloride....................................................
Potassiumferrichexacyanoferrate(II)2H20(Prussianblue)......................................................
Potassiumiodide..........................................................
Potassiumpermanganate.......................................
Prednisolone............................................................
Primaquine...............................................................
Procainamide..............................................................
Procainebenzylpenicillin.........................................
Procarbazine...............................................................
Procyclidine
Proguanil..................................................................
Promethazine............................................................
Propranolol..............................................................
Propylthiouracil......................................................
Protaminesulfate....................................................
Prussianblue.............................................................
Pyrantel......................................................................
Pyrazinamide.............................................................
Pyridostigmine..............................................................
Pyridoxine...................................................................
Pyrimethamine..........................................................
Quinidine.......................................................................
Quinine.........................................................................
Rabiesimmunoglobulin............................................
Rabiesvaccine
Ranitidine.....................................................................
Retinol...........................................................................
Ribavirin....................................................................
Riboflavin..................................................................
Rifampicin...................................................................

Rifampicin+isoniazid...............................................
Rifampicin+isoniazid+ethambutol.......................
Rifampicin+isoniazid+pyrazinamide..................
Rifampicin+isoniazid+pyrazinamide+ethambutol............................................................
Risperidone
Ritonavir....................................................................
Rotavirusvaccine.
Rubellavaccine
Salbutamol................................................................
Salicylicacid.............................................................
Saquinavir(SQV).....................................................
Seleniumsulfide.........................................................
Senna.........................................................................
Silversulfadiazine...................................................
Simvastatin...............................................................
Sodiumcalciumedetate............................................
Sodiumchloride...........................................................
Sodiumfluoride.......................................................
Sodiumhydrogencarbonate.................................
Sodiumlactate..........................................................
Sodiumnitrite............................................................
Sodiumnitroprusside....................................................
Sodiumstibogluconate
Sodiumthiosulfate...................................................
Sodiumvalproate.....................................................
Spectinomycin...........................................................
Spironolactone.........................................................
Stavudine..............................................................
Stavudine+lamivudine+nevirapine...................
Streptokinase..............................................................
Streptomycin..............................................................
Sulfadiazine..................................................................
Sulfadoxine...............................................................
Sulfadoxine+pyrimethamine...............................
Sulfamethoxazole......................................................
Sulfamethoxazole+trimethoprim......................
Sulfasalazine...........................................................
Suxamethonium......................................................
Tamoxifen...................................................................
Tenofovirdisoproxilfumarate.............................
Testosterone................................................................
Tetanusvaccine..
Tetracaine..................................................................
Tetracycline...............................................................
Theophylline.
Thiamine...................................................................
Thiopental...................................................................

Timolol.......................................................................
Trimethoprim.............................................................
Tropicamide..............................................................
TyphoidVaccines.
Tuberculin,purifiedproteinderivative(PPD)..........
Urea...........................................................................
Valproicacid.........................................................
Vancomycin..................................................................
Vecuronium................................................................
Verapamil.................................................................
Vinblastine..................................................................
Vincristine..................................................................
Warfarin....................................................................
Waterforinjection...................................................
Yellowfevervaccine
Zidovudine...........................................................
Zidovudine+lamivudine.......................................
Zidovudine+lamivudine+nevirapine................
Zincsulfate...............................................................