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Energy Requirement Equations Basal Energy Expenditure (BEE) Harris-Benedict Men: 66 + (13.7 x W) + (5.0 x H) (6.8 x A) Women: 655 + (9.

.6 x W) + (1.7 x H) (4.7 x A) W (Kg) H (cm) A(years) STRESS FACTORS (% of BEE to provide daily calorie needs) Starvation 0.85 1.0 Normal / Non-Stressed 1.2 1.3 S/P elective surgery w/o complications 1.25 1.35 Mod stress from chronic illness 1.35 1.5 Sev stress from acute illness, severe infection, trauma, or ventilation 1.5 Burns > 20% of total BSA 2 or >

EST. DAILY PROTEIN REQUIREMENTS

Normal / Non-Stressed 0.8 g/Kg Oncology/Stressed/Surgical 1 1.5 g/Kg Sev stress/burns/mult trauma 1.5 2.5 g/Kg Bone marrow transplant 2 g/Kg* Renal failure (no dialysis) 0.6 0.8 g/Kg Renal failure (w dialysis) 1.2 1.5 g/Kg** Hepatic encephalopathy 0.4 g/Kg * unless in renal failure ** depends on BUN/Scr NITROGEN BALANCE (+2 to +5 is goal) N2 Balance = (N2 in) (N2 out) N2 in = Protein intake (g) / 6.25* N2 out = 24 hour urine urea Ns (UUN) + 4** * 6.25 g protein provides 1 g Nitrogen (standard oral diet) ** where 4 = insensible N2 losses (stool, sweat, hair, etc.)

Electrolyte Maintenance Sodium Chloride 1-2-3 mEq/Kg/day Acetate Phosphate Potassium Chloride 0.5-1-2 mEq/Kg/day Acetate Phosphate 12-15 Mol/1000kcal Calcium Gluconate 5 mEq/L Magnesium Sulfate 8-24 mEq/day 12-16 mEq/day BOLD indicates most appropriate DAILY FLUID REQUIREMENTS Based on weight First 10 Kg 100 mL/Kg Second 10 Kg 50 mL/Kg All Kg > 20 Kg 20 mL/Kg OR 30-35 mL/Kg (25 mL/Kg for elderly patient)

LIPID CALORIES 10% fat 20% fat Daily Dose 50 kcal/day 1000 kcal/day Every 275 kcal/day 500 kcal/day Other Day Mon/Thur ONLY 157 kcal/day 286 kcal/day

Dextrose Calories = 3.4 kcal/g Protein Calories = 4 kcal/g BLOOD GASES pH / PCOs / HCO3 / %O2 Blood Gas Disorders pH HCO3 pCO2 Respiratory Acidosis Respiratory Alkalosis Metabolic Acidosis Metabolic Alkalosis

FLUID COMPOSITIONS (mEq/L) Na K Cl HCO3- L/day Diarrhea 50 35 40 45 varies Ileostomy 140 20 100 25 0.5 - 2.0 Gastric 80 10 100 -2.0 Bile 145 5 100 40 1.5 Pancreatic 140 5 75 85 0.75-1.0 Fluid and Electroylte Abnormalities in TPN Management [PF = Predisposing Factors] [MGT = Management] Hypovolemia PF-GI losses, osmotic diuresis; MGT- increased fluid intake Hypervolemia PFrenal failure, excess fluid intake; MGT-decreased fluid intake Hyponatremia PF-GI losses, fluid overload, diuretics; MGT-varies with cause Hypernatremia PF-dehydration; MGTincrease fluid intake Hypokalemia PF-GI losses, diuretics, anabolism; MGT-increase K+ intake Hyperkalemia PF-renal failure; MGTdecrease K+ intake Hypophosphatemia PF-phosphate binding antacids, anabolism, PO4-free dialysis; MGT-D/C PO4 binders, increase phosphate intake Hyperphosphatemia PF-renal failure; MGT-decrease phosphate intake

Hypomagnesemia PF-diarrhea, malabsorption, anabolism; MGT-increase Mg++ intake Hypermagnesemia PF-renal failure; MGTdecrease Mg++ intake Hypercalcemia PF-cancer, hyperparathyroidism; MGT-decrease Ca++ in TPN, cautious volume expansion, drug treatment Hypocalcemia PF-hypoalbuminemia, chronic renal failure; MGT-increase Ca++ intake in CRF only Metabolic Acidosis PF-diarrhea, high output fistula, renal failure, excess amino acid intake; MGT-decrease Cl- in TPN, increase acetate in TPN Metabolic Alkalosis PF-gastric losses; MGT-increase Cl- in TPN, decrease acetate in TPN

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