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  • 99mTc งานMedchem

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    Tok Keawkaew
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    This document discusses technetium-99m medronic acid, which is used in bone imaging. It provides background on technetium-99m production via fission or fusion and extraction from molybdenum-99 generators. It then focuses on bone scan procedures using technetium-99m medronic acid, including administration, imaging times, and interpretation of scans to evaluate bone abnormalities. The document also explains that technetium-99m medronic acid uptake in bone is related to osteoblastic activity and skeletal blood flow.

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    99mTc--งานMedchem

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    This document discusses technetium-99m medronic acid, which is used in bone imaging. It provides background on technetium-99m production via fission or fusion and extraction from molybdenum-99 generators. It then focuses on bone scan procedures using technetium-99m medronic acid, including administration, imaging times, and interpretation of scans to evaluate bone abnormalities. The document also explains that technetium-99m medronic acid uptake in bone is related to osteoblastic activity and skeletal blood flow.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
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    34 views4 pages

    99mTc งานMedchem

    Uploaded by

    Tok Keawkaew
    This document discusses technetium-99m medronic acid, which is used in bone imaging. It provides background on technetium-99m production via fission or fusion and extraction from molybdenum-99 generators. It then focuses on bone scan procedures using technetium-99m medronic acid, including administration, imaging times, and interpretation of scans to evaluate bone abnormalities. The document also explains that technetium-99m medronic acid uptake in bone is related to osteoblastic activity and skeletal blood flow.

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    Attribution Non-Commercial (BY-NC)
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    of 4

    Technetium (99mTc) medronic

    IUPAC : Methylenebis(phosphonic acid)


    technetium (99mTc)

    Formula : CH6O6P2 x99mTc

    99m
    Tc
    (Diagnostic radiopharmaceuticals)
    (Gamma emitting) (Positron
    emitting)

    Bone imaging
    99- (99mTc)
    in vivo

    6.02
    140 keV
    80%

    99mTc
    -99 (99Mo)
    67
    99mTc 86% 99Tc 14%
    99Mo -235 (235U)
    (fission) 99Mo
    high specific activity 99Mo

    (fusion) 98Mo 99Mo


    99mTc technetium
    generator
    2
    . (wet
    column or closed column)
    . (dry
    column or openned column)

    1. Bone scan
    Bone scan
    (99mTc
    MDP(Methylenediphosphonate) 20 mCi
    200Ci/kg, minimum 0.5-1 mCi)
    2-3

    [Whole body scan]

    99mTc MDP

    1.

    1 3-4

    2. 1-2
    ( 1-2 )

    3.

    (


    )
    4.
    /


    40

    2-4 (
    ) 2-3

    99mTc MDP
    chemisorptions surface hydroxyapatite crystal

    uptake

    99m

    Tc MDP

    1.osteoblastic activity
    osteoblastic activity uptake

    2.skeletal blood flow


    uptake

    uptake

    ..
    http://en.wikipedia.org/wiki/Technetium_(99mTc)_medro
    nic_acid

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