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:

()

=S

= P

, G

S P. -

:=

E+S->ES->EP->E+P

pH

():

, kcat

/S vs I/Km
E+S->ES->EP->E+P

Vmax, Km

->

Km =

Vmax =

I ->E / I ->ES

Km =

Vmax =

-> ES

Km =

Vmax =

S)

ES- (

ES

ES)

pH

pH

Ser, Thr -> /


, (-)


()

-> -> > .

. .
, 2010

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