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Serge Renaud, : , , (2001)

Blackburn Henri, The low risk coronary male, Am. J. cardiology, 58,1986 , p161
3
Burros, Marian (29 March 1995). "Eating Well
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Mediterranean diet pyramid: a cultural model for healthy eating". American Journal of Clinical Nutrition
61: 1402S1406S. June 1995.
5
Bruno Simini, "Serge Renaud: from French paradox to Cretan miracle" The Lancet 355:9197:48 (1
January 2000)
6
Mayo Clinic. "Olive Oil: Which Type Is Best?." ScienceDaily 14 August 2007. 19 November 2007
7
Keys Ancel, How to eat and stay well, the Mediterranean way New York: Doubleday Co. Inc, 1975


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Keys Ancel, Seven Countries. A multirative analysis of death and coronary heart disease, Harvard
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: American Heart Association,
.
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"Lyon Diet Heart Study".

de Lorgeril M, Salen P, Martin JL, Monjaud I, Delaye J, Mamelle N. (1999). "Mediterranean diet,
traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report
of the Lyon Diet Heart Study". Circulation 99 (6): 77985. PMID 9989963.

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Role of fibre and fruit in the Mediterranean diet to protect against myocardial infarction:
a case-control study in Spain, European Journal of Clinical Nutrition 2002;56:715-722,
2002.

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Adherence to a Mediterranean Diet and Survival in a Greek Population, The New England
Journal of Medicine 2003;348:2599-2608, 26 2003.

16


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19

Conformity to traditional Mediterranean diet and cancer incidence: the Greek EPIC
cohort , British Journal of Cancer 2008;99:191-195,doi:10.1038/sj.bjc.6604418, 2008.

18


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Effect of olive oils on biomarkers of oxidative DNA stress in Northern and Southern
Europeans , FASEB Journal (Federation of American Societies for Experimental Biology
Journal) 2007;21(1), .
22

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Oleic acid, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu
(erbB-2) expression and synergistically enhances the growth inhibitory effects of
trastuzumab (HerceptinTM) in breast cancer cells with Her-2/neu oncogene amplification,
Annals of Oncology 2004;doi:10.1093/annonc/mdi090, 2005.
24

National Cancer Institute

Wine Drinking and Risk of Non-Hodgkins Lymphoma among Men in the United States:
A Population-based Case-Control Study, American Journal of Epidemiology 2002;156:454462, 16 2002.
25

21


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Men's Health Forum

Polyphenols in red wine inhibit the proliferation and induce apoptosis of LNCaP cells,
British Journal of Urology 2002;89:950-954, 2002.
30

24


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31

Onion and garlic use and human cancer, American Journal of Clinical
Nutrition 2006;84:1027-1032, 2006.

25


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Cancer Prevention and Education Society

Food and Nutrition Information Center
34
Varietal Differences in Phenolic Content and Antioxidant and Antiproliferative Activities
of Onions, Journal of Agricultural and Food Chemistry 2004;52(22):6787 - 6793, 3
2004
33

26


..:
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27

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Allium Vegetables and Risk of Prostate Cancer: A Population-Based Study, Journal of

the National Cancer Institute 2002;1648-1651, 6 2002.

27


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28

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37

National Cancer Institute

Journal of the National Cancer Institute 2002;94:391-398, 6 2002

28


..:
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29

36%
.

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.

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.

38

A comparison of lycopene and orchidectomy vs orchidectomy alone in the management

of advanced prostate cancer, British Journal of Urology 2003;92(4):375, 2003.

29


..:
o

30

PSA 78%
40%

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. , 15%

3.
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International Journal of Cancer 2001;94:128-134, 1 2001.

30


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31

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32

. 40

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2007,
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40

International Research Conference on Food, Nutrition and Cancer , American Institute for
Cancer Research 2004, 15 .
41

Journal of Nutrition, American Society for Nutritional Sciences 2004, .

42

Annual Meeting, American Association for Cancer Research 2007, .

Cancer
43

Cancer Prevention and Education Society

32


..:
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33

,
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DNA
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. 44

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44

BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and

genistein in breast and prostate cancer cells, British Journal of Cancer 2006;94:407-426, 24
2006.

33


..:
o

34

.

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.



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International Research Conference on Food, Nutrition and Cancer , American Institute for
Cancer Research 2004, 15 .

34


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35

,
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20 ,
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4.
.
.

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5.
46

Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of

Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors, Proceedings of
the National Academy of Sciences 2002;99:7610-7615, 28 2002.
47
Fruits, vegetables and risk of renal cell carcinoma: A prospective study of Swedish
women, International Journal of Cancer 2005;113(3):451-455, 20 2005.

35


..:
o

36

.



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American Journal of Epidemiology 2001;153;1142-1147, 15 2001.

36


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37

, 19%
. 49
National Cancer Institute, :
,
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.
170 60
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48
.

: ;
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.
.
49

A citrus a day keeps the doctor away, Commonwealth Scientific and Industrial Research
Organization, CSIRO 3 2003
50

Diet, Nutrition and the Prevention of Chronic Disease, World Health Organization Geneva,
2003.

37


..:
o

38

.
2005, Cancer
Research UK, ,
.


.
,
.
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.
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Cordyceps,
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stuffing). .
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, . 52
51

Anti-Aromatase Activity of Phytochemicals in White Button Mushrooms (Agaricus

bisporus), Cancer Research 2006;66(24):12026-12034, 15 2006.
52

Cancer Research UK

38


..:
o

39

, , :
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inositol pentakisphosphate
(IPP).
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.

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Inhibition of the Phosphatidylinositol 3-Kinase/Akt Pathway by Inositol Pentakisphosphate

Results in Antiangiogenic and Antitumor Effects, Cancer Research 2005;65:8339-8349, 15
2005.
53

Inhibition of the Phosphatidylinositol 3-Kinase/Akt Pathway by Inositol

Pentakisphosphate Results in Antiangiogenic and Antitumor Effects, Cancer
Research 2005;65:8339-8349, 15 2005.

39


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40

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54

Honey-bee products in prevention and/or therapy of murine transplantable tumours,

Journal of the Science of Food and Agriculture 2004;10.1002/jsfa.2041,(early online publication),
3 2004

40


..:
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41

.
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55

Dairy Foods, Calcium, and Colorectal Cancer: A Pooled Analysis of 10 Cohort Studies,
Journal of the National Cancer Institute 2004;96:1015-1022

41


..:
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42

. .

, , .
.
D, 60%
.

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.
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.
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56

Vitamin D and calcium supplementation reduces cancer risk: results of a randomized

trial , American Journal of Clinical Nutrition 2007;85:1586-1591, 2007.
57

Intakes of Calcium and Vitamin D and Breast Cancer Risk in Women , Archives of Internal
Medicine 2007;167:1050-1059, 2007.
58
Plasma vitamin D metabolites and risk of colorectal cancer in women, Cancer
Epidemiology, Biomarkers and Prevention 2004;13:1502-1508, 2004.

42


..:
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43

,
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59

Red Meat Enhances the Colonic Formation of the DNA Adduct O6-Carboxymethyl
Guanine: Implications for Colorectal Cancer Risk, Cancer Research 2006,66:1859-1865,
, 2006
60

Meat, Fish, and Colorectal Cancer Risk: The European Prospective Investigation into
Cancer and Nutrition , Journal of the National Cancer Institute 2005;97:906-916, 15
2006.

43


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Phenolic Content of Virgin Olive Oil Improves Ischemic Reactive Hyperemia in

Hypercholesterolemic Patients, Journal of the American College of Cardiology 2005;46:18641868, 15 2005
63

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46


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The Effect of Polyphenols in Olive Oil on Heart Disease Risk Factors, Annals of Internal
Medicine 2006;(145):333-341, 5 2006..
65
Food and Nutrition Information Center

47


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Nut Consumption and Decreased Risk of Sudden Cardiac Death in the Physicians'
Health Study, Archives of Internal Medicine 2002;162:1382-1387, 24 2002.

49


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68

Acute Effects of High-Fat Meals Enriched With Walnuts or Olive Oil on Postprandial
Endothelial Function, Journal of the American College of Cardiology 2006;48:1666-1671, 17
2006.
69

Dose Response of Almonds on Coronary Heart Disease Risk Factors: Blood Lipids,
Oxidized Low-Density Lipoproteins, Lipoprotein(a), Homocysteine, and Pulmonary Nitric
Oxide: A Randomized, Controlled, Crossover Trial, Circulation 2002;106:1327-1332;
published online before print as doi:10.1161/01.CIR.0000028421.91733.20, 10
2002.

51


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52


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C Reactive protein, moderate alcohol consumption, and long term prognosis after
successful coronary stenting: four year results from the GENERATION study,
Heart 2004;90:419-424, 2004.

53


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54

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72

Alcohol Consumption and Cardiovascular Disease Mortality in Hypertensive Men,

Archives of Internal Medicine 2004;164:623-628, 22 2004.
73
Comparative effects of quercetin and its predominant human metabolites on adhesion
molecule expression in activated human vascular endothelial cells,
Atherosclerosis 2007;doi:10.1016/j.atherosclerosis.2007.07.040, 2007.

54


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55

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55


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77
"The effect of fruit and vegetables intake on risk for coronary heart disease", Annals of
Internal Medicine 2001;134:1106-1114, 19 2001.
76

56


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Dietary Potassium Deficiency Is Independently Associated with Increased Blood

Pressure in a Multi-Ethnic Population-Based Cohort, American Society of
Nephrology 2008;Abstract, 41st Annual Meeting, 8 2008.

57


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58

,
.
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Approaches to Stop Hypertension" (DASH),
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79

Hypertension
Flavonoid intake and cardiovascular disease mortality: a prospective study in
postmenopausal women , American Journal of Clinical Nutrition 2007;85:895-909,
2007.
80

58


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59

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Association for Eradication of Heart Attack

Plasma Vitamin C Modifies the Association Between Hypertension and Risk of Stroke,
Stroke 2002; 33:1568-1573, 2002.
82

59


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60

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83

Dietary Lycopene, Tomato-Based Food Products and Cardiovascular Disease in

Women, Journal of Nutrition, American Society for Nutritional Sciences 2003;133:2336-2341,
2003.

60


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61

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61


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62

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62


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63

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Circulation 2004,10.1161/01.CIR.0000138154.00779.A5, 2004.

63


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64

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"Fish and omega-3 fatty acid intake and risk of coronary heart disease in women",
Journal of the American Medical Association 2002;287:1815-1821, 10 2002.
88

"Blood levels of long-chain n3 fatty acids and the risk of sudden death", The New
England Journal of Medicine 2002;346:1113-1118, 11 2002.
89

Journal of the American Medical Association Vol. 285 No.3, 17 2001

64


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65

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90

Adherence to Mediterranean diet and risk of developing diabetes: prospective cohort

study, British Medical Journal 2008;doi:10.1136/bmj.39561.501007.BE, 29 2008.

65


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66

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American Diabetic Association

Protective effect of fruits, vegetables and the Mediterranean diet on asthma and
allergies among children in Crete, Thorax 2007;published online
first:doi:10.1136/thx.2006.069419, 5 2007.
92

66


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67


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Diet, wheeze, and atopy in school children in Menorca, Spain , Pediatric Allergy and
Immunology 2007;18(6):480-485, 2007
95

Maternal Food Consumption During Pregnancy and Asthma, Respiratory and Atopic
Symptoms in 5-Year-Old Children, American Thoracic Society 2007, International conference,
Session A105; Abstract 726; Poster Board # 901, (Thorax; in press), 20 2007.

68


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69

, 40%
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98
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97

69


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70

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Dietary intake of fatty acids and fish in relation to cognitive performance at middle age,
Neurology 2004;62:275-280, 27 2004.

70


..:
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71

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100

Cigarette Smoking, Fish Consumption, Omega-3 Fatty Acid Intake, and Associations
With Age-Related Macular Degeneration: The US Twin Study of Age-Related Macular
Degeneration, Archives of Ophthalmology 2006;124:995-1001, 2006.
101

Dietary Fatty Acids and the 5-Year Incidence of Age-Related Maculopathy, Archives of
Ophthalmology 2006;124:981-986, 2006.

71


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72

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102

Hormone Therapy and Age-Related Macular Degeneration: The Women's Health

Initiative Sight Exam Study, Archives of Ophthalmology 2006;2006;124:988-992,
2006.
103
An experimental study of a Mediterranean diet intervention for patients with rheumatoid
arthritis, Annals of the Rheumatic Diseases 2003;62:208-214, 2003.

72


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73

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104

Mediterranean diet intervention in rheumatoid arthritis, Annals of the Rheumatic

Diseases 2003;62:193-195, 2003.

73


..:
o

74

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Bone mineral density and dietary patterns in older adults: the Framingham
Osteoporosis Study, American Journal of Clinical Nutrition 2002;76:245-252, 2002.

74


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75

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. 50 , 65%
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106

Anti-inflammatory Activity of a High-molecular-weight Cranberry Fraction on

Macrophages Stimulated by Lipopolysaccharides from Periodontopathogens, Journal of
Dental Research 2006;85:235-239, 2006.
107

Red Wine Polyphenols Modulate the Oxidative Stress Induced by

Periodontopathogens, International Association for Dental Research 2006;abstract #1080, 35th
Annual Meeting of the American Association for Dental Research, 10 2006.

75


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76

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110
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109

76


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77

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verbena)

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111

Chronic melatonin treatment reduces the age-dependent inflammatory process in

senescence-accelerated mice, Journal of Pineal Research 2007;42(3):272279,
2007.
112
Age-dependent lipopolysaccharide-induced iNOS expression and multiorgan failure in
rats: Effects of melatonin treatment, Experimental Gerontology 2006;41(11):1165-1173,
2006.
113

American Geriatrics Society

77


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78

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114

Phytochemistry: Ibuprofen-like activity in extra-virgin olive oil, Nature 2005;437,45-46,

doi:10.1038/437045a, 1 2005.

78


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79

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1984 2000. 6.608
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115

British Nutrition Foundation

Gastroenterology
117
Fruit and Vegetable Consumption and Risk of Cholecystectomy in Women, American
Journal of Medicine 2006;119(90):760-767, 2006.
116

79


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80

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. ,
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119

Clinical Gastroenterology and Hepatology

http://www.incardiology.gr/odigies/paxisarkia.htm

80


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81

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New England Journal of Medicine

81


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82

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