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Anesthesia for organ donation:

COMMON PHYSIOLOGIC DERANGEMENTS AFTER BRAIN DEATH


Condition Cause
Hypotension Hypovolemia (DI; hemorrhage) Neurogenic shock

Hypoxemia Neurogenic pul edema, Pul contusion, Pneumonia


Gastric aspiration, Fluid overload

Hypothermia Hypothalamic infarction, Exposure

Dysrhythmia Intracranial injury or herniation, Hypothermia


(especially bradycardia) Hypoxia, Electrolyte abnormality
Myocardial contusion, ischemia
 Avoid vasopressors  may cause visceral ischemia
 Consider using low dose Dopamine if needed
 They are atropine resistance
 Consider use NDMR due to somatic spinal reflex
 No need for GA, for  BP consider use vasodilators

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