Conference: Focus On The Hepatitis B Virus

ASIAN PACIFIC ASSOCIATION FOR THE
STUDY OF THE LIVER

SINGLE TOPIC CONFERENCE
FOCUS ON THE VIRUS HEPATITIS B
3-6 OCTOBER 2015 YEREVAN, ARMENIA
SCIENTIFIC PROGRAMM
www.apaslstc-armenia2015.com
Dear colleagues,
ladies and gentlemen!
On behalf of the Ministry
of Healthcare of the Republic of
Armenia and me personally I
cordially welcome the participants of
the International Conference: Focus
on the Hepatitis B.
Viral Hepatitis is polyetiologic
group of diseases, which is
responsible for 1,5 million deaths
each year. Most of them are associated with HBV-infection. Around
600 million people, or every 11-th person in the world are currently
living with HBV and HCV infection. They are at serious risk of
developing the liver cirrhosis and hepatocellular carcinoma. That
is why, viral hepatitis is recognized as a global public healthcare
problem in the world.
I am glad, that this Conference, organized on the initiative of
Armenian Hepatological Forum, has unified the leading specialists
and doctors of various fields not only from Armenia and CIS
countries, but also from Europe, Asia and the USA.
In medicine, as in any other area it is impossible to achieve any
progress without cooperation. Moreover, one can hardly imagine the
modern medicine without the international experience in evidencebased medicine. In this context collaboration with specialists,
advanced medical centers, laboratories and international associations
could have a tangible contribution in finding the most efficient ways
for the solution of the pressing issues of Hepatology.
I wish constructive dialogue and fruitful work to all the
participants of the Conference.
Minister of Healthcare Republic of Armenia,
MD, professor
Armen Muradyan
2 www.apaslstc-armenia2015.com
Dear Colleagues,
On behalf of the Organizing Committee, it is a great honor and pleasure for me to invite you to
the Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference (STC) on
HBV in Armenia. The conference will be held in October 3-5, 2015, in Yerevan. This is the first time
that an APASL event will take place in this new region.
The conference will focus on all aspects of the management of Hepatitis B Viral Infection and
will include the important topics of epidemiology, virology and immunology of HBV Infection as
well as optimal current and future treatment approaches for patients with HBV Infection. It will
be one of the sequential APASL conferences on HBV with the aim to invite all experts in the field
from the different regions of the world, to present the latest research and clinical data. The Scientific
program of the conference is supported by a key international advisory group.
Yerevan is regenerated community based on the ancient city Erebuni which was founded
by Urartian King Argishti I (r. ca. 785753 BC) in 782 BC. It was built on the top of a hill called
Arin Berd overlooking the Arax River. Yerevan is one of the worlds oldest continuously inhabited
cities. The city is a home to dozens of museums, art galleries, and libraries as well as to the largest
Armenian Church in the world, the Cathedral of Saint Gregory the Illuminator, opened in 2001
when the entire Armenian nation had celebrated the 1700th anniversary of the establishment of the
Armenian Church and the adoption of Christianity as a state religion in Armenia. Yerevan is as old
as its traditions and culture.
Yerevan is also famous for its Brandy (Cognac) where there is a leading Brandy Company with
its main brand name Ararat.
Our guests will enjoy Armenian cuisine as well as the cuisine of other countries in the finest
restaurants and cafes.
There is a large exhibition market next to the Republic Square where you can buy Armenian
national souvenirs, handcrafts, clothes and accessories. October is the best season to visit Armenia.
The weather is mild; it is warm and mostly sunny. It is called gold season with its beautiful autumn
shades so called Saryans colors. There are many Public Holidays in October. The main is ErebuniYerevan which is an event dedicated to the capital of Armenia.
We hope you will enjoy this conference as well as your stay in Armenia, the country with an
extensive and rich history, culture and amazing traditions and hospitality.
We are looking forward to see you in Armenia.
With kindest regards
President of APASL
STC 2015 in Armenia
Hasmik Ghazinyan MD, PhD
Co-Chairman
Gagik Hakobyan MD, PhD
Secretary General
Ara Asoyan MD, PhD
ACKNOWLEDGEMENTS
PLATINUM SPONSOR
SPONSORS
SCIENTIFIC
PROGRAMM
Saturday, October 3
10:00-20:00
Registration
Sunday, October 4
09:00-09:15
Opening Ceremony
09:1511:55
Session 1 HBV: Overview of Epidemiology and Burden of

Disease
Chairs: Osuma Yokosukao, Sang Hoon Ahn, Ara Asoyan, Gayane
Melik-Andreasyan, Tsaxik Vardanyan
09:1509:30
The Changing Epidemiology of HBV in Asia

Sang Hoon Ahn, South Korea
09:30-09:45
The Changing Epidemiology of HBV in Mongolia

Oidov Baatarkhuu, Mongolia
09:45-10:00
The Changing Epidemiology of HBV in Europe

Pierre Van Damme, Belgium
10:00-10:15
The Changing Epidemiology of HBV in North America

Ray Kim, USA
10:15-11:55
Epidemiology of HBV Infection in CIS countries
10:15-10:25
Epidemiology of HBV Infection in Russia

Vladimir Chulanov, Russia
10:25-10:35
Epidemiology of HBV Infection in Ukraine

Larisa Moroz, Ukraine
10:35-10:45
Epidemiology of HBV Infection in Belarus

Igor Karpov, Belarus
10:45-10:55
Epidemiology of HBV Infection in Georgia

David Metreveli, Georgia
10:55-11:05
Epidemiology of HBV Infection in Moldova

Iuliana Lupasco, Moldova
11:05-11:15
Epidemiology of HBV Infection in Kazakhstan

Alexander Nersesov, Kazakhstan
11:15-11:35
Epidemiology of HBV Infection in Armenia

Hasmik Ghazinyan, Gayane Melik-Andreasyan,
Gayane Sahakyan, Armenia
11:35-11:55
Discussion
11:55-12:25
Coffee break
12:25-13:30
Session 2 - VIROLOGY AND IMMUNOPATHOGENESIS

Chairs: Richard Moreau, Tigran Davtyan, Robert Gish, Irakli
Rtskhiladze, Ara Babloyan
12:25-12:40
Covalently Closeed Circular (ccc) DNA is the only reason,

unable clear HBV; May need Immunological Atttack?
Masao Omata, Japan
12:40-12:55
HBV Genotypes and Core and Pre-core Mutations

Robert G Gish, USA
12:55-13:10
Interactions Between HBV, Host Immunity and the liver

Tigran Davtyan, Armenia
13:10-13:30
Discussion
13:30-14:30
Lunch
14:30-16:30
Session 3 - NATURAL HISTORY

Chairs: Massao Omata, Oidov Baatarkhuu, Narine Pashinyan,
David Metreveli, Ray Kim
14:30-14:45
Natural History of Chronic Hepatitis B and

Predictors of Disease Progression (viral and host)
Diana A.Payawal, Philippines
14:45-15:00
Occult HBV Infection: Clinical Significance

Saeed Hamid, Pakistan
15:00-15:15
HBV - HCC
Kim Ray, USA
15:15-15:30
Discussion
15:30-15:50
Acute - on - Chronic liver failure (ACLF)

Shiv Kumar Sarin, India
15:50-16:05
HBV - ACLF
Richard Moreau, France
16:05-16:20
The Role of Non-invasive Markers and Imaging in

Staging liver Disease in Chronic HBV Infection
Salimur Rahman, Bangladesh
16:20-16:30
Discussion
16:30-17:00
Coffee Break
17:00-18:00
SESSION 4 - TREATMENT INDICATIONS AND OPTIONS

Chairs: Hasmik Ghazinyan, Diana A. Payawal, Larisa Moroz,
Vladimir Chulanov, Gamal Shiha
17:00-17:20
HBV: Treatment Indications and Therapeutic End-points

Shiv Kumar Sarin, India
17:20-17:40
Is Clearance of HBsAg and cccDNA a Realistic Target?

Robert G. Gish, USA
17:40-17:55
Discussion
17:55-18:00
First Day Closing

Faculty Dinner including Social Program
Monday, October 5
09:00-11:00
SESSION 5 - CURRENT TREATMENT FOR CHB

Chairs: Manoj Kumar Sharma, Pierre Bedossa, Saeed Hamid,
Igor Karpov, Violeta Sargsyan
09:00-09:15
Treatment of Patients with CHB with Pegylated Interferon:

Clinical Significance of HBV DNA and HBsAg Quantitative
Testing
Alaaeldin Ibrahim, Egypt
09:15-09:30
NAs as First-line Therapy for CHB

Gamal Shiha, Egypt
09:30-09:45
Monitoring and Management of NAs failures

Vladimir Chulanov, Russia
09:45-10:00
Risk factors of HCC during nucleic acid

treatment on chronic hepatitis B
Osamu Yokosuka, Japan
10:00-10:20
Management of CHB patients with Decompensated Cirrhosis

Chay Dai, Taiwan
10:20-10:40
Can Cirrhosis be Really Reversed? A focus on the

Parenchymal Extinction Nodule
Pierre Bedossa, France
10:40-11:00
Discussion
11:00-11:30
Coffee Break
11:30-13:30
SESSION 6 - CHB in SPECIAL POPULATIONS

Chairs: Barjesh Sharma, Mamun Al-Mahtab, Gagik Hakopyan,
Luliana Lupasco, Chia Yen Dai
11:30-11:50
Management of CHB in the Immunosuppressed Patients

Narina Sargsyants, Armenia
11:50-12:10
Management of CHB in Children

Mamun- AL- Mahtab, Bangladesh
12:10-12:30
Management of CHB in Pregnancy

Hasmik Ghazinyan, Armenia
12:30-12:50
Management of CHB in Co-infected Patients (HBV - HCV ),

and (HBV - HIV )
Violeta Sargsyan, Armenia
12:50-13:10
Management of CHB in Renal Disease and Renal

Failure Patients
Barjesh Sharma, India
13:10-13:30
Discussion
13:30-14:30
Lunch
14:30-16:00
SESSION 7 INTERACTIVE CASE STUDY DISCUSSIONS

ON THE TREATMENT OF CHB (DIFFICULT- TO- TREAT CASE
SCENARIOS) AND WHO-POLICY
Chairs: Robert G. Gish, Narina Sargsyants, Antons Mozalevskis,
Alexander Nersesov, Aregnaz Mkhitaryan
14:30-14:45
Case-Based_Management HBV reactivation

Robert Gish, USA
14:45-15:00
UNUSUAL CASE OF HIGHLY REPLICATIVE HBV VIRUS

INFECTION WITH EXTRAHEPATIC MANIFESTATIONS
Narina Sargsyants, Armenia
15:00-15:15
Hepatitis B reactivation after pagylated interferon

plus ribavirin in chronic HBV/HCV coinfected
Taiwanese patient
Chia-Yen Dai, Taiwan
15:15-15:30
Case of HBV related chronic liver disease presenting

as acute hepatitis
Mamun- AL- Mahtab, Bangladesh
15:30-15:45
Managment of chronic Hepatitis D

Alexander Nersesov, Kazakhstan
15:45-16:05
WHO - Policy
Antons Mozalevskis, WHO
15:05-16:15
Discussion
16:15-18:00
SESSION 8 - WHAT IS ON THE HORISON FOR

TREATMENT OF CHB? NEW TARGETS FOR HBV
Chairs: Gerardo Enrique Guilleen, Pavel Bogomolov, Salimur
Rahman, Alaaeldin Ibrahim, Hasmik Ghazinyan
16:15-16:35
Treatment of HBV Beyond the Guidelines

Manoj Kumar Sharma, India
16:35-16:55
Other New Therapies

Robert G Gish, USA
16:55-17:10
Myrcludex B, an NTCP- specific Inhibitor of HBV

and HDV Entry
Pavel Bogomolov, Russia
17:10-17:20
Immune Based Therapies for CHB

Gerardo Enrique Guilleen, Cuba
17:20-17:40
Discussion
17:40-18:00
Meeting Closing
GALA DINNER INCLUDING SOCIAL PROGRAM
October 6
17:00-19:00
Satellite Symposium
Roche
INVITED
SPEAKERS
11
DR. SHIV KUMAR SARIN

Prof. S.K. Sarin, is a Senior Professor of Hepatology and Director, Institute
of Liver and Biliary Sciences (ILBS). He is an astute clinician, a pioneer in
clinical protocol innovations, a gifted teacher, front-line clinical researcher with
great insights into basic sciences, an educationist and above all an enthusiastic
learner.
Dr. Shiv Kumar Sarin obtained his MMBS degree with seven gold medals
(1974), his MD in General Medicine (1978) from Rajasthan University and his DM
in Gastroenterology from the AIIMS in 1981. He moved to the G.B. Pant Hospital
of Delhi University in 1983 and became the Head of Gastroenterology in 1997.
He is currently the Professor & Head, Department of Hepatology and Founder
Director, Institute of Liver & Biliary Sciences, New Delhi first of its kind in Asia.
His research interests include Portal hypertension, Chronic hepatitis B, C
and liver cancer. He has made outstanding contribution in the pathogenesis
and management of bleeding in liver diseases. His seminal contributions
to understanding portal hemodynamics, non-cirrhotic portal hypertension
and approach for Primary Prevention of Variceal Bleeding by band ligation
and endotherapy based on Sarins Classification of Gastric Varices have
significantly improved the management protocols. His proposal of changing
the nomenclature of Hepatitis B carrier to Chronic HBV Infection is widely
accepted. He has helped define two new disease entities; Portal Biliopathy and
Acute-on-Chronic Liver Failure (ACLF).
He has published over 350 original articles in prestigious journals like
New England Journal of Medicine, The Lancet, Annals of Internal Medicine,
Gastroenterology and Hepatology, AJP, JCI. He has edited 9 books. He led the
development of five major global guidelines for the Asian Pacific Association for
the Study of the Liver (APASL). These are widely quoted and practiced.
He was awarded the Padma Bhushan in 2007 for his overall seminal
contributions to the Medical field in India. He has received Shanti Swarup
Bhatnagar Award, Third World Academy of Medical Sciences (TWAS)
International Prize, Om Prakash Bhasin Award, Ranbaxy Medical Sciences
Award, Dhanvantri Medical Award and the Best Teacher Award, Amrut Mody
Research Foundation Award, Hoechst Om Prakash Foundation Award, Fogarty
International Fellowship, Dr. Dharamveer Datta Memorial Oration of ICMR,
Olympus J. Mitra Award, Rotary Award, Rashtriya Samman Puraskar of IEDRA,
Lifetime Acheivements Award of Delhi Govt., Knoll Oration Award of ISG, Netaji
Oration of API, Mike Mosnal Lecture of SAGES, South Africa, Dr. V.R. Khanolkar
Oration of ICMR, Silver Jubilee Research Award of MCI, Dr. Y.S. Row Award of
INSA, FICCI Award, Dr. Kunti Om Prakash Award of ICMR, Bhagwan Mahaveer
Award, DRC Gold Medal Oration, Malaysia Liver Foundation Award and the Most
Distinguished Physicians from India by American Association of Physicians of
Indian origin, USA.
He is the founding Chief Editor of a prestigious international Journal,

Hepatology International (Springer International).
Dr. Sarin served as the President of Asian Pacific Association for the Study of
the Liver (APASL) and now as Chairman of the steering committee.
He was nominated to lead the Medical Council of India (MCI) as the Chairman
of the Board of Governors, 2010-2011. He developed with other BOGs the
Vision 2015 document for Medical Education in India. He introduced far
reaching reforms in medical education and health sciences.
He has started the Yellow Ribbon Campaign for hepatitis prevention in India
in 1998, which has become a national movement now.
Dr. S K Sarin has been instrumental in the establishment through the Govt of
Delhi, the Institute of Liver and Biliary Sciences (ILBS) in India, which is also the
first Deemed to be University in the field of Liver and Biliary Diseases globally.
13
BARJESH CHANDER SHARMA

Professor, Department of Gastroenterology Govind Ballabh Pant Hospital,
New Delhi-2, India
EXPERIENCE IN GASTROENTEROLOGY
1. Senior Resident (Hepatology) 2 years PGIMER, Chandigarh.
2. DM Resident (Gastroenterology) 3 years SGPGIMS, Lucknow
3. Senior Research Associate (Gastroenterology) 13 months GB Pant
Hospital, Delhi, PGIMER, Chandigarh
4. Assistant Professor (Gastroenterology) 33 months PGIMER, Chandigarh
5. Associate Professor (Gastroenterology) 5 years and 3 months GB Pant
Hospital, Delhi
6. Professor (Gastroenterology) 1/4/2005 Present GB Pant Hospital, Delhi.

RESEARCH EXPERIENCE
1. Papers published 197
2. Submitted for publication 8
3. Papers presented/abstracted 237
4. Conferences/Workshops attended 56
JOURNAL EDITOR, MEMBER AND OFFICE BEARER OF SCIENTIFIC
COMMITTEES AND SOCIETIES
1. Secretary-General cum Treasurer of APASL.
2. Member of Steering Committee of APASL.
3. Chairman of Guidelined Committee of APASL
4. Member of Executive Council of APASL.
5. Member of Indian Society of Gastroenterology.
6. Member of Society of Gastrointestinal Endoscopy.
7. Member of Indian Association for Study of Liver Diseases.
8. Member of Asian Pacific Association for Study of the Liver
9. Editor
- Journal of Gastroenterology and Hepatology 2004; 19: Supplement
- Postgraduate course and current reviews in Hepatology, 14th Biennial
Conference of Asian Pacific Association for the study of the Liver
10. Assistant Editor for Journal Hepatology Intennational
11. Member of Editorial Board of World Journal of Gastroenterology.
12. Member of Editorial Board og J Gastroenterol Hepatol.
13. Member of Editorial Board of Journal of Clinical and Experimental
MANOJ KUMAR SHARMA

Current position: Additional Professor, Institute of Liver & Biliary Sciences,
New Delhi, India (April 2014 Now)
Past Positions: Associate Professor, Institute of Liver & Biliary Sciences,
New Delhi, India (April 2010 March 2014)
Advanced Endoscopy Fellow, Beth Israel Deaconess Medical Center,
Harward Medical School, Boston, MA, USA (July 2014 Nov 2014)
Assistant Professor, Institute of Liver & Biliary Sciences, New Delhi, India
(June 2008 March 2010)
Assistant Professor, Department of Gastroenterology at G B Pant Hospital,
New Delhi India. (June 2006 May 2008)
PUBLICATIONS ORIGINAL ARTICLES: 100
PUBLICATIONS: REVIEWS: 50
REVIEWER
1. GASTROENTEROLOGY
2. HEPATOLOGY INTERNATIONAL
3. ANTIVIRAL THERAPY
4. J HEPATOLOGY
5. Indian J of Gastroenterology
EDITORIAL BOARD AND ASSOCIATE EDITOR
1. HEPATOLOGY INTERNATIONAL
15
OSAMU YOKOSUKA
M.D., Ph.D.
EDUCATION
1969 1975 M.D Chiba University School of Medicine
RESEARCH AND PROFESSIONAL EXPERIENCES
19751976 Resident in Chiba University Hospital
19761978 Medical staff, Kimitsu Central Hospital
19781980 Clinical Observer, Clinical assistant, Research Fellow:
(Royal Free Hospital School of Medicine, London University,
Prof.S.Sherlock, Prof.BH Billing)
19781985 Research Fellow: First Department of Medicine,Chiba University
(Prof.K.Okuda, Dr.M.Omata)
1983 Research Fellow (Fox Chase Cancer Center, Dr.J.Summers)
19851992 Assistant Professor, First Department of Medicine, Chiba
University
19851986 Research Fellow: Biology Department, National Cancer Center
Institute (Dr.S.Nishimura)
19922006 Lecturer, First Department of Medicine, Chiba University
2006 Professor and Chairman, Department of Medicine and Clinical
Oncology, Post graduate school of Medicine, Chiba University
20092011 Vice Director of Chiba University Hospital
20092014 Secretary General cum Treasurer of APASL
20112013 Chiba University Councilor
2012 Professor and Chairman,Department of Gastroenterology and
Nephrology, Chiba University Graduate School of Medicine
20132015 Dean Chiba University Graduate School of Medicine
20142015 President Elect of APASL
2015 President of APASL
1986 Degree: Doctor of Medical Science (Chiba University)
MEMBERSHIP
Japanese Gastroenterology Association,
Japan Association For the Study of Liver Disease,
International Association for the Study of Liver Disease, etc
Asian Pacific Association for the Study of Liver Disease,
Associate Editor: J Gastroenterol Hepatol (19891993)
Associate Editor: Liver International (20032007)
Associate Editor: Hepatology Research (2006)
Associate Editor: Hepatology International (2007)
MAJOR FIELD OF INTERST
Viral Hepatitis, Hepatocellular Carcinoma
SAEED SADIQ HAMID

Dr. Saeed Sadiq Hamid is The Ibne Sina Professor of Medicine and
Chairman, Department of Medicine at The Aga Khan University, Karachi,
Pakistan. He graduated from King Edward Medical College, Lahore in 1981, and
has been affiliated with AKU since 1990. He completed his postgraduate training
in Medicine and Gastroenterology in the UK, and in Hepatology at University of
Texas Southwestern Medical School, Dallas, USA.
His research interests include Viral Hepatitis and Acute Liver Failure. He has
been the recipient of basic and clinical research grants, including clinical trials.
He has a total of 135 peer reviewed publications and three book chapters to his
credit, and currently serves as an associate editor for Hepatology International,
the official journal of APASL.
Dr. Hamid has been a Member of the Executive Council, Asian Pacific
Association for the Study of the Liver, 2006-2010, and currently also serves as
President, Pakistan Society for the Study of Liver Diseases. He has been a long
serving member of the WGO Guidelines and Publications committee and also a
member of many guideline development groups of the APASL, as well as WHO.
17
MAMUN AL-MAHTAB
Dr. Mahtab graduated from Mymensingh Medical College, Bangladesh in
1995. He did MSc in Gastroenterology from University of London, UK in 1998
and subsequently did MD in Hepatology from Bangabandhu Sheikh Mujib
Medical University, Dhaka, Bangladesh in 2006. He is a Fellow of the American
College of Gastroenterology.
Dr. Mahtab is working as an Associate Professor at the Department of
Hepatology, Bangabandhu Sheikh Mujib Medical University. He has conducted
several clinical trials, which have been presented at international conferences
and published in regional and international peer-reviewed journals.
He has compiled four books, namely Liver: A Complete Book on HepatoPancreato-Biliary Diseases, published by Elsevier, Comprehensive Text Book
on Hepatitis B, published by Jaypee, Fatty Liver Disease and Hepatitis
Management Update published by McMillan and Text Book of HepatoGastroenterology published by Jaypee.
He is serving in the Editorial Boards of several international journals in
the fields of Hepatology and Gastroenterology including Euroasian Journal of
Hepato-Gastroenterology (journal of Euroasian Gastroenterological Association),
Journal of Clinical and Experimental Hepatology (journal of Indian Association for
the Study of the Liver), World Journal of Hepatology, Hepatitis Monthly, Journal
of Global Infectious Diseases to name a few.
He has received awards for scientific works from different major international
bodies including American Association for the Study of Liver Diseases (AASLD),
World Gastroenterology Organization (WGO), Asian Pacific Association for the
Study of the Liver (APASL), International Association for the Study of the Liver
(IASL), Euroasian Gastroenterological Association (EGA), Japan Society of
Hepatology (JSH), Indian National Association for the Study of the Liver (INASL),
Turkish Hepato-Biliary-Pancreatology Association (HEBIPA), Asia-Pacific Primary
Liver Cancer Expert (APPLE) Association and Association of Physicians of
Bangladesh (APB).
He has more than 110 international and over 35 national publications, more
than 160 international and over 35 national conference abstracts and over
90 international conference talks to his credit, of these the most prestigious
one being Blumberg Oration 2015 conferred by Kalinga Gastroenterology
Foundation, India.
Dr. Mahtab is member of the APASL Working Parties on hepatitis B, Hepatitis

C, acute on chronic liver failure (ACLF) and liver fibrosis.
He is the Secretary General, Association for the Study of the Liver, Dhaka,
Bangladesh (the national Hepatology Association of Bangladesh). He is also the
founder Secretary General of Viral Hepatitis Foundation Bangladesh, a nongovernment service provider and research organization in Bangladesh. He is a
Member of European Association for the Study of the Liver (EASL) and a Life
Members of Asian-Pacific Association for the Study of Liver (APASL) and Indian
National Association for the Study of the Liver (INASL).
19
OIDOV BAATARKHUU
MD., PhD
Position: Professor and Chairman
Institution: Department of Infectious Diseases School of Medicine, Mongolian
National University of Medical Sciences
Professor O.Baatarkhuu graduated from the Mongolian National Medical
University and obtained his degree in Doctor of Medicine with commendation
in 1994. He has received his PhD degree at the Postgraduate School, Health
Sciences University of Mongolia in 2006. He is currently Professor of Medicine,
Head of Department of Infectious Diseases, School of Medicine, Mongolian
National University of Medical Sciences and General Expert on Infectious
Diseases of Ministry of Health, Mongolia.
He has completed his postdoctoral Fellowship in Hepatology at the
Department of Internal Medicine, Severance Hospital, Yonsei University College
of Medicine, Seoul, Korea between 20072008. He did second overseas Clinical
Research Fellowship in Hepatology at the Department of Internal Medicine
III, AKH Hospital, University of Vienna, Austria in 2012. Also currently he has
completed as a Clinical Research Fellow in Hepatology at the Storr Liver unit,
Westmead Millennium Institute for Medical Research, University of Sydney,
Australia. He has also been a Visiting Professor at the Victorian Infectious
Diseases Laboratory, Melbourne, Australia in 2014.
Professor O.Baatarkhuu is an Executive Council Member of APASL, Member
of CEVHAP, President of the Mongolian Association for the Study of the Liver
Diseases, Executive Director of the Mongolian Infectious Diseases Physicians,
General Expert of Infectious Diseases of Ministry of Health, Mongolia, Board
member of Mongolian Society of Virology, Academic Member of Scientific
Committee of the National Center for Communicable Diseases, Mongolia and
Chairman of the Scientific Committee for the APASL-STC 2012 in Mongolia.
Professor O.Baatarkhuu is a key investigator in more than 10 international
and national trials on antiviral treatment of chronic hepatitis B and C. He has
received numerous local, national and international research awards.
He has been extensively involved in research in the fields of viral hepatitis and
hepatocellular carcinoma and he is currently working on the natural history of
hepatitis B in Mongolia.
Professor O.Baatarkhuu has published more than 125 international and local
papers. He also has spoken nationally and internationally on viral hepatitis and
chronic liver diseases including hepatocellular carcinoma.
Research interest: Epidemiology, prevention, molecular virology, and
treatment of viral hepatitis B, C, D and Liver cirrhosis and HCC.
SALIMUR RAHMAN
Professor Salimur Rahman is a veteran Hepatologist of Bangladesh and
at present working as professor of Hepatology Bangabandhu Sheikh Mujib
Medical University which is the only medical university of this country. He is one
of the founders of the discipline in this country. He is a co-editor of 1) Liver: A
Complete Book on Hepato-Pancreato-Biliary Diseases and 2) Comprehensive
Text Book of Hepatitis B published by Elsevier and Jaypee respectively.
Professor Rahman has over 100 publications in international and regional
journals. He is Editor-in-Chief of Euroasian Journal of Hepato-Gastroenterolgy,
the official publication of Euroasian Gastroenterological Association and Viral
Hepatitis Foundation Bangladesh. He is the Member of the Editorial Board of
Hepatology International. He is the current President of Association for the Study
of the Liver, Dhaka, Bangladesh the National Association of Hepatologists
of the country and the President of Association of Physicians of Bangladesh
the premier platform of specialist physicians of Bangladesh. He is also the
founder Chairman of Viral Hepatitis Foundation Bangladesh. He served as
member national committee for Hepatitis B virus in Bangladesh and served as
executive committee member of Asian Pacific Association for the study of the
Liver (APASL). He is the current president of South Asian Association for the
Study of Liver (SAASL). Professor Salimur Rahman is a leading interventionist
of Bangladesh and has pioneered the transformation of Hepatology from a
theoretical to an interventional super-specialty in this country. He is a senior
faculty member of the Department of Hepatology, Bangabandhu Sheikh Mujib
Medical University. He is a Fellow of Bangladesh College of Physicians and
Surgeons, Royal College of Physicians of Edinburgh and Royal College of
Physicians of Dublin.
21
DIANA ALCANTARA PAYAWAL

MD, MSc, FPCP, FPSG, FPSDE
Graduate
Fellowship in Hepatology, Interventional Sonology and Digestive Endoscopy
and Molecular Biology, Department of Gastroenterology, University of Tokyo,
Tokyo Japan through a scholarship Ministry of Education, Japanese
Government (MOMBUSHO).
Fellowship in Gastroenterology and Digestive Endoscopy Unit, Digestive
Endoscopy of University of Santo Tomas, Manila, Philippine.
Master/Diploma, Tropical Medicine and Hygiene, Degree School of Tropical
Medicine, Mahidol University, Bangkok, Thailand through scholarship
Southeast Asia Ministry of Education (SEAMEO).
Residency Training in Internal Medicine Department of Internal Medicine,
Cardinal Santos Medical Center.
Faculty of Medicine and Surgery University of Santo Tomas, Manila,
Philippines.
Academic Position
Asst. Professor Faculty of Medicine and Surgery Univerisity of Santo Tomas
Asst. Professor Faculty of Medicine Fatima Medical Univerisity Hospital
Past and Present Position:
1. Head, Digestive Health Unit, Fatima Medical Center 2011-present
2. Asst Head Section of Gastroenterology, Cardinal Santos Medical Center
2011present
3. Chairman, Training Committee, Cardinal Santos Medical Center
2001present
4. Chairman, Hospital Research Committee, Fatima Medical University
Hospital
5. Executive Council Board, Asia Pacific Study of the LIVER (APASL) 2011
2015
6. President, Hepatology Society of the Philippines 20122014 (March)
7. President, Philippine Society of Gastroenterology 20102011
8. Regional Member IC-HEP 2014present
9. Editorial Board, Hepatology International 2015present
10. Steering Committee, Asian Pacific Study of the Liver (APASL) 20142015
11. Advisory Board, APASLJapan 2016
12. Advisory Board APASLTurkey 2015
13. Course Director, First Radiofrequency Ablation workshop and Hands-on
Training for Liver Cancer, CSMC, 2015
14. Core Committee, Guidelines on Hepatitis B Screening and Treatment,
Hepatology Society of the Philippines, 2014
15. Core Committee, Guidelines on Colon Cancer Screening, Philippine

Society of Gastroenterology 2014
16. Core Committee, Guidelines on Hepatitis B Screening and Treatment,
Hepatology Society of the Philippines, 2014
17. Chairman, Committee on Advocacy, APASL 2013-2015
18. President, Asia Pacific Study of the LIVER (APASL) Single topic
Symposium Liver Cancer 2013, Cebu
19. Philippine Heart Center-Institution Ethics Review Board 2014 up to
resent
20. Internatonal Advisory Board Asia Pacific Study of the LIVER (APASL)
2013
21. Associate Editor, Philippine Journal of Medicine
22. International Reviewer, Hepatology International
23. Co-founder Asia Pacific Digestive Cancer Alliance 2010
23
PROF GAMAL SHIHA

MD, MSc, FPCP, FPSG, FPSDE
Affiliations:
Prof. Internal Medicine. Dept. GI and liver unit; Mansoura faculty of medicine.
Head of the Egyptian Liver Research Institute And Hospital (ELRIAH).
20142015 Study Principal Investigator
Study Title: A phase III, Randomized, Open-Label Study, for the Treatment of
Egyptian Adults with Chronic HCV Infection Genotype 4.
Site: Specialized Medical Hospital, Mansoura University.
Study Title: A Phase III Randomized, Open-Label Study for the Treatment of
Egyptian Adults with Chronic Genotype 4 HCV Infection.
Site: Egyptian Liver Research Institute And Hospital (ELRIAH)
Study Title: Randomized, placebo-controlled, multi-center study to assess the
efficacy and safety of a new drug in thrombocytopenic subjects
with hepatitis C virus (HCV) infection who are otherwise eligible to
initiate antiviral therapy.
Study Title: DFPP for Chronic Hepatitis C Virus.
Recent Published papers
Wahid Doss, Gamal Shiha. Sofosbuvir Plus Ribavirin for Treating Egyptian
Patients With Hepatitis C Genotype 4. Journal of Hepatology 2015.
Shiha G, Samir W, Seif S, EldesokyA, Soliman R. The CC allele at
rs12979860 IL28B is associated with higher hepatic fibrosis in HCV
atients with genotype 4. Accepted Poster. Hepatology 2014, Supplement 1,
no. 1843.
Gamal E. Esmat, Gamal Shiha, Rabab F. Omar, Mohamad, Hassany, Radi
Hammad, Marwa Khairy, Waleed Samir, Reham Soliman, et al. Sofosbuvir
plus Ribavirin in the Treatment of Egyptian Patients with Chronic Genotype
4 HCV Infection. Accepted Poster. Hepatology 2014, Supplement 1, no. 959.
Rakhi Maiwall, Shiv K. Sarin, Chandan K. Gamal Shiha, Utility Of A
Modified PIRO (Predisposition, Injury, Response, Organ Failure) Model For
Predicting Kidney Failure In Patients With ACLF- A Multinational Cohort
Study. Accepted Poster. Hepatology 2014, Supplement 1, no. 1843. No. 578.
ALAAELDIN IBRAHIM
M.D
Prof. of Medicine, Former chief of GI/Liver unit, Faculty of Medicine, University
of Benha, Egypt.
Have been graduated from Qasr El Ayny Medical School, Cairo University
on 1982. Have been awarded Master Degree and Degree of Doctorate from
University of Benha, Egypt. Have been trained in gastroenterology and
hematology at Cairo University, University of Benha and Maady military hospital,
Egypt. Have part of his postgraduate and post-doctorate training at the Royal
Free hospital, and St Marks Hospital; London, UK. Have been invited as a
speaker and moderator in many national and International meetings. Awarded
the degree of full Professor of Medicine in 1996. Had the post of Chief of Liver/
GI division University of Benha, the director of endoscopy unit and the director of
the internal medicine University hospital, Benha, Egypt. Have been visiting many
medical recognized centers globally. Have been elected as executive council
member (ECM) for APASL and the vise-Chair of public health committee on 2012
till now. Have co-Chaired the two APSASL STC on Liver fibrosis that have been
held in Cairo, Egypt on 2008 and 2014. He is a member in many local, regional
and International societies. He is a member of APASL, EASL, ESGE and ASGE.
Have many local and international publications in the field of hepatology and
gastroenterology. His main interests are, NAFLD, liver fibrosis, liver emergencies
and viral hepatitis C.
25
CHIA-YEN DAI
M.D. PhD
FACULTY:
Professor, School of Medicine, College of Medicine, Kaohsiung Medical
University
Professor, Institute of Graduate Medicine, College of Medicine, Kaohsiung
Medical University
Professor, Institute of Clinical Medicine, College of Medicine, Kaohsiung
Medical University
EDUCATION:
M.D. Kaohsiung Medical University, Kaohsiung, Taiwan
Master in Medical Science, Institute of Medical Science, Kaohsiung Medical
University
PhD. in Medical Science, Institute of Medical Science, Kaohsiung Medical
University
LICENSURE AND CERTIFICATION:
National Medical Board of Republic of China
Board of Internal Medicine, R.O.C.
Board of Gastroenterology, R.O.C.
Board of Critical Care Medicine, R.O.C.
Board of Digestive Endoscopy R.O.C.
Board of Environmental and Occupational Medicine, R.O.C.
POSTDOCTORAL TRAINING
19961998 Gastroenterology training, Division of Hepatology, Department
of Medicine, Kaohsiung Medical University Hospital, Taiwan
1998 Research Fellow, Division of Hepatology, Kyoto University, Kyoto
19981999 Critical Care Medicine training, Department of Emergency
Medicine, Kaohsiung Medical University Hospital, Taiwan
19992001 Occupational Medicine training, Department of Occupational
Medicine, Kaohsiung Medical University Hospital, Taiwan

MAJOR RESEARCH INTERESTS:
1. Molecular epidemiology of hepatitis C virus infection in Taiwan
2. Treatment of patients with acute and chronic hepatitis C
3. Molecular epidemiology of GB virus C/hepatitis G virus infection in Taiwan
4. Molecular epidemiology of TT virus infection in Taiwan
5. Treatment of chronic hepatitis B patients
MAJOR ADMINISTRATIVE RESPONSIBILITIES:

2007 now Chief, Department of Occupational Medicine, Kaohsiung Medical
University Hospital
2009 now Chief, Health Management Center, Kaohsiung Medical University
Hospital
2008 now Professor, School of Medicine, College of Medicine, Kaohsiung
Medical University
2012 now Vice Secretary General, Gastroenterology Society of Taiwan
(GEST)
Publication
More than 180 SCI papers (first author: 52; corresponding author: 15)
published.
27
RAY KIM
MD
W. Ray Kim, MD, is Professor and Chief in the Division of Gastroenterology
and Hepatology at Stanford University School of Medicine. Prior to assuming
this post in November 2013, Dr. Kim was Professor of Medicine at Mayo Clinic
College of Medicine.
Dr. Kim earned his medical diploma at Seoul National University in Korea.
After residencies in medicine at Seoul National University and University
of Arkansas for Medical Sciences, he underwent subspecialty training in
gastroenterology and hepatology as well as receiving a Certificate of Added
Qualification in liver transplantation, both at Mayo Clinic in Rochester, MN. He
also holds a Master in Science Degree in patient oriented research from Seoul
National University and a Master in Business Administration from University of
Pennsylvania.
Dr. Kims research interest has been in epidemiology and outcomes and
comparative effectiveness studies in viral hepatitis and end stage liver disease.
His research has been funded by several NIH grants, one of which is credited for
the seminal achievement of producing the Model for End Stage Liver Disease
or the MELD score. MELD has been rapidly accepted in the past decade as a
standard by which to assess severity of liver failure in patients with end stage
liver disease.
Dr. Kim has been active in several professional societies and not-for-profit
organizations. He is the current Treasurer and a member of the Governing Board
at the American Association for the Study of Liver Disease (AASLD). He is also a
founding trustee of the AASLD Foundation. He has been an Associate Editor of
Hepatology and served on a number of editorial boards.
Dr. Kim practices general and transplant hepatology with emphasis on
viral hepatitis, liver cancer and pre-and post-operative care of liver transplant
recipients. As a Division Chief as well as full-time faculty at Stanford University,
he is actively engaged in the education of undergraduate and medical students,
residents and fellows as well as junior faculty members.
ROBERT GISH
MD, DSc, Professor
Director of Center for Hepatobiliary Disease and Abdominal Transplantation
(CHAT) University of California, San Diego, CA, USA
More than 20 years, Professor Robert Gish is a leader expert in a
hepatological practice, particularly, in hepotological function disorders, liver
transplantology, viral hepatitis, liver cancer. More than 22,000 patients with
different hepathological disorders have a chance to improve their quality of
life by getting appropriate treatment by him. Moreover, Mr. Gish implement an
enhanced programme for prevention, screening and treatment of hepotological
diseases, hepatitis B in South Africa and Vietnam for which he has been honored
with the Humanitarian of the Year Award.
Dr. Robert Gish graduate from Medical University of Kansas city, after which
he continued his fellowship residency at the Gastroenterology and Hepatology at
the University of California, Los Angeles.
He is a member of the American Association for the Study of the Liver, the
American Gastroenterological Association, the American Society of Transplant
Physicians, and the International Liver Transplant Society, and etc. Professor
Gish has published more than 500 original articles, reviews, abstracts, and book
chapters regarding all aspects of liver disease and transplantation.
29
RICHARD MOREAU
MD
Degree:
1983: M.D., University of Paris
Academic Appointments:
1996 Date Director of Research (Senior Scientist) at the French NIH
(Inserm) Grade 2 (1996), Grade 1 (2009), Outstanding (2014)
19962004 Head of group in the Lebrecs lab (successively at Inserm Unit
24 and 481), Clichy, France
2005 Date Head of Team (Complications of cirrhosis) at UMR_S 773,
Centre de Recherche Biomdicale Bichat-Beaujon CRB3, Inserm and
Universit Paris Diderot, Clichy/Paris, France.
2013 Chairman, UMR_S 773, Centre de Recherche Biomdicale Bichat
Beaujon CRB3, Inserm and Universit Paris Diderot, Clichy/Paris, France.
2014 Date Vice-Chairman, UMR_S1149, Centre de Recherche sur
lInflammation CRI, Inserm and Universit Paris Diderot, Clichy/Paris, France.
2013 Date Co-Chairman, with Prof. Shiv Sarin (Institute of Liver and Biliary
Sciences, ILBS, New Delhi, India) of an International Associated Laboratory
entitled Associated Laboratory of Transcriptomics and Metabolomics for
Liver Diseases.
Hospital Appointments:
19831996 Physician in Intensive Care Units of Ile-de-France
1996Date Consultant in Liver Unit, Beaujon Hospital (successively Headed
by Profs J-P Benhamou, S Erlinger, D Valla, and F Durand), Assistance
Publique Hpitaux de Paris (APHP), Clichy, France
Society Membership:
American Association for the Study of Liver Diseases
European Association for the Study of the Liver
French Speaking Society of Intensive Care Medicine
French Association of the Study of the Liver (Scientific Committee, 2005
2007)
International Ascites Club (Scientific Committee, 19942003)
Awards:
2009: Colombian Society of Gastroenterology
2014: Czech Society of Hepatology
2014: Award Scientific Excellence (Inserm)
Editorial Activities:
19972001: Associate Editor, Gastroentrologie Clinique et Biologique
20012008: Co-Editor: Gastroentrologie Clinique et Biologique
20022006: Editorial Board, Hepatology
20072009: Editorial Board, Journal of Hepatology
20072009: Associate Editor, Liver International
September 2010-Date: Editorial Board, Hepatology

20102014: Associate Editor, Journal of Hepatology
20152018: Senior Editor, Journal of Hepatology French Organization of
Research:
2008-Date: In charge of the Liver Branch at the Inserm Institute called
Pathophysiology, Metabolism, Nutrition (Head, Prof C. Boitard).
2010-Date: Elected as Member of the Council advising the Dean of the
Faculty of Medicine, University Paris Diderot, Paris
2013-Date: Member of the Steering Committee (SC) at the Dpartement
Hospitalo-Universitaire (DHU) UNITY (for Addressing Unmet Needs
through Innovation in HepaTology and GastroenterologY), Beaujon
Hospital, APHP, Clichy, France
2012 Date: Partner of the Laboratoire dExcellence (Labex) Inflamex,
ComUE Sorbonne Paris Cit, Paris, France.
International Steering Committes (SCs):
June 2009 Date: Member of the SC of the Consortium EASL-CLIF (for
Chronic Liver Failure); 2011: Principal Investigator of the CANONIC Study
on Acute-on-Chronic Liver Failure.
20102013: Member of the SC of the Special Interest Group on Portal
Hypertension of the American Association for the Study of Liver Diseases.
Scientific Production:
289 Peer-Reviewed publications (PubMed, June 2015),of which 207 original
articles, 82 Review Articles or Editorials; h-index: 51
Editor of 1 book
24 book chapters,
200 Invited conferences (70% outside France), > 250 communications in
International meetings.
31
PIERRE BEDOSSA
M.D. PhD
Pierre Bedossa is Professor of Pathology at the University Paris-Diderot,
France. He is currently Head of the Department of Pathology, Physiology and
Nuclear Medicine at the Groupe Hospitalier Paris Nord. He is Chairman and
Head of the Department of Pathology at Beaujon Hospital, Paris FRANCE.
Pierre Bedossa is specialized in liver pathology. He is the leader of the
METAVIR group and of the FLIP pathology consortium. He has produced new
scoring systems in chronic hepatitis and NAFLD. His research interests have
focus on dynamic of liver fibrosis, the cellular mechanisms leading to progression
and regression, and evaluation methods of liver fibrosis.
From 2001 to 2013, he was appointed as director of the research team
pathophysiology of liver diseases (CNRS UMR 8147) and he is currently the
team leader of cirrhosis and liver cancer group at the Center for Biomedical
Research, INSERM U773, Paris, France. He was a member of the editorial board
of Journal of Hepatology (19911996), Hepatology (20012006), Journal of
Pathology (since 2002) and Associate editor of Virchows Archiv of Pathology
(20032012). He has published more than 350 original articles in peer-reviewed
journals and 16 Book chapters. Pierre Bedossa is the current president of the
European Society of Pathology.
ANTONS MOZALEVSKIS
Dr. Antons Mozalevskis is currently working as a Medical Officer at the WHO
Regional Office for Europe in Copenhagen, Denmark. He is responsible for all
viral hepatitis-related activities at the Regional Office and technical support to the
Member States in the Region.
He completed his medical training and residency in Family Medicine at Riga
Stradins University, Latvia. He worked as a clinician for 7 years and was involved
in a number of civil society and professional organisations active in the field
of HIV/viral hepatitis prevention and research. In 2012 2014, he completed
the European Programme for Intervention Epidemiology Training (EPIET) and
received a Master Degree in Applied Epidemiology from the National School of
Public Health in Madrid, Spain.
Dr. Mozalevskis has over 10 years of experience in the field of Public
Health, HIV and viral hepatitis, including being a member of Latvian National
Coordination Committee for HIV, STI and Viral Hepatitis in the past, and a
member of several regional and international expert networks.
33
VAN DAMME PIERRE

Pierre Van Damme is full professor at the University of Antwerp, Faculty
of Medicine and Health Sciences. He chairs the Vaccine & Infectious Disease
Institute (VAXINFECTIO, University of Antwerp); VAXINFECTIO is a consortium
of three research units within the university: the Laboratory of Medical
Microbiology (LMM), the Laboratory of Experimental Hematology (LEH), and
the Centre for the Evaluation of Vaccination (CEV). It is recognized as Centre
of Excellence of the University of Antwerp and functions as WHO Collaborating
Centre for the WHO European Region for the control and prevention of infectious
diseases.
The CEV was founded in 1994 by Pierre Van Damme. The centre conducts
research in 5 main areas: (1) (sero-)epidemiology of infectious diseases; (2)
economic evaluation of public health interventions and mathematical modelling
of infectious diseases; (3) assessment of protective efficacy and effectiveness
of vaccines; (4) injection and diagnostic device research; (5) kinetics of vaccineinduced antibodies, including passive transfer of maternal antibodies.
Pierre Van Damme gained his MD from the University of Antwerp in 1984. He
was recruited in 1985 to work on the epidemiology and prevention of hepatitis B
in institutions for the mentally retarded. He subsequently obtained post-graduate
degrees in health and economics, the evaluation of human corporal damage, and
a master degree in occupational health. He obtained his PhD in epidemiology
and social medicine in 1994 from the University of Antwerp, Belgium.
In 2000, he was appointed Professor at the Faculty of Medicine and
Health Sciences, University of Antwerp he teaches infectious diseases and
vaccinology in the Faculty of Medicine and Health Sciences as well as in the
Faculty of Pharmacy and Biomedical Sciences. He has authored more than 300
peer-reviewed papers and is on the editorial board of several scientific journals
that focus on the study of vaccines and vaccine-preventable infectious diseases.
Professor Van Damme was awarded with the Research Award of the University
of Antwerp, and in 2000 with the Belgian Social Medicine Award Jean Van
Beneden for his work on the introduction of universal hepatitis B immunization
programs. In May 2014, he was awarded with the prestigious Bill Marshall award
of the ESPID society.
Since 1994, he has served as the executive secretary of the Viral Hepatitis
Prevention Board, a group of international experts dealing with topics on
prevention and control of viral hepatitis. His current research projects at
the University are focused on the epidemiology and prevention of vaccinepreventable infectious diseases, such as hepatitis A, hepatitis B, diphtheria,
pertussis, varicella, rotavirus, measles, HSV, influenza, and HPV. His research
also concerns occupational health, youth health and preventive health for sex
workers. Since 1985 he has conducted more than 300 vaccine trials within the
trial unit of Centre for the Evaluation of Vaccination.
He has been for more than 10 years a regular advisor for national and
international organizations, including the Flemish Vaccination platform, the
National Immunization Technical Advisory Group, and the World Health
Organization (European Regional Office and Headquarters). He has been
appointed as chairman of the European Technical Advisory Group of Experts on
communicable diseases and vaccines for the WHO European Region (ETAGE).
35
GERARDO ENRIQUE GUILLEN NIETO

Degree: Master of Science Organic chemist, 1986, Odessa University.
Ukraine. Ph.D. on Biological Sciences, Havana University, 1995
Senior Researcher
Current Position: Biomedical Research Director Centro de Ingeniera

Gentica y biotecnologa Havana, Cuba
Other relevant information:
146 papers published on vaccinology and drug developmet (molecular
biology, immunology, preclinical and clinical evaluation).
41 patents granted or filled in Europe, USA, Japan and other relevant
countries.
Vaccine development experience on hepatitis, dengue, meningitis, pertussis,
combine vaccines and cancer vaccines.
Member of the Expert Vaccine Committee of the Ministry of Science and
Technology of Cuba.
Member of the Cuban Academy of Science elected for the period 2012
2016.
Awards:
19932014 42 annual awards of Cuban Academy of Science for scientific
results.
20022010 8 awards of the Ministry of Health for a best published scientific
papers of the year.
2010 Award World Office Intellectual property
2008 Award 485 Anniversary of Havana City for upstanding results on
Science.
2005 C.J. Finlay Medal of the Cuban State Council, awarded for
upstanding results on Science
2003 TWAS (Third World Academy of Science) award on Biology.
SANG HOON AHN

M.D., Ph.D.
1 Department of Internal Medicine,
2 Institute of Gastroenterology
3 Brain Korea 21 Project for Medical Science Yonsei University College of
Medicine, Seoul, Republic of Korea.
Sang Hoon Ahn, M.D., PhD, is a Professor of Yonsei University College
of Medicine and a director of Referral Centre, Severance Hospital, Yonsei
University Health System, Seoul, Republic of Korea.
He has completed a Postdoctoral Fellowship at Liver Research Centre in
Brown Medical School, USA (2001003). His career has been advanced during
his sabbatical years at Victorian Infectious Diseases Reference Laboratory
(VIDRL), WHO Collaborating Centre in Australia (20082009).
He was a Chairman of the Academic Committee of Korean Liver Cancer
Study Group (20102011) and the Asia Pacific Primary Liver Cancer Expert
Meeting (APPLE 2013). He currently is a Chairman of the Publicity Committee
of Korean Association of the Study of the Liver (KASL) (20142015). He is
an advisor for the Ministry of Health and Welfare and the Ministry of Food and
Drug Safety in Korea and a global advisory board member/speaker of many
international pharmaceutical companies.
His major research interests include chronic hepatitis B, C, cirrhosis and
liver cancer. He has completed and is complementing over 50 outstanding
clinical trials as a principal investigator. He has over 200 SCI publications
(Gastroenterology, Hepatology, Gut, Journal of Hepatology, etc as the first
author) including book chapters and review articles in peer-reviewed journals. His
invited oversea lectures are over 120 times around the world.
Prof. Sang Hoon Ahn is an Editor of Journal of Gastroenterology and
Hepatology, Academic Editor of PLoS ONE and Special Section Editor of
Gut and Liver. He is also an editorial board of Journal of Hepatology, Liver
International, World Journal of Gastroenterology, Hepatology International,
World Journal of Hepatology, World Journal of Virology, Gastroenterology and
Hepatology Research, American Journal of Cancer Science, American Journal
of Cancer Review. He sits on reviewer for NEJM, Lancet, Gastroenterology, Gut,
Hepatology, etc.
37
VLADIMIR CHULANOV
M.D., Ph.D.
Head of Reference Centre for Viral Hepatitis
Head of Clinical Diagnostics and Research Centre
Central Research Institute of Epidemiology
Dr. Vladimir Chulanov received his M.D. degree from Sechenov Moscow
Medical Academy in 1995. In 1997 he completed a residency at the Infectious
Diseases Department and received Ph.D. degree in 2003. From 2001, Dr.
Chulanov worked in the Central Research Institute of Epidemiology as a scientific
researcher and then as Deputy Head of the Center for Molecular Diagnostics. In
2007, he was appointed Head of the Clinical Diagnostics and Research Center,
a position he still holds. In 2008, Dr. Chulanov became Head of the Reference
Center for Viral Hepatitis, where he oversees an extensive research portfolio.
Areas of Specialty
Epidemiology, Molecular Epidemiology, Diagnostics, Prevention and
Management of Viral Hepatitis and other Infectious Diseases
Current Position and Affiliation
Current Head of Reference Centre for Viral Hepatitis, Head of Clinical
Diagnostics and Research Centre at the Central Research Institute of
Epidemiology, Moscow, Russia
Education
1995 Graduated from Sechenov Moscow Medical Academy
1995 1997 Post-Graduate fellowship in Infectious Diseases at Sechenov
Moscow Medical Academy
2001 2002 International Emerging Infectious Diseases Fellowship, CDC,
Division of Viral Hepatitis, Atlanta, USA
2003 Received PhD from Sechenov Moscow Medical Academy
Membership
Member of the Expert Group for Viral Hepatitis under the Russian Ministry
of Health
European Association for the Study of the Liver
American Association for the Study of Liver Diseases
International Society for Infectious Diseases
Russian Society for the Study of the Liver
Russian National Scientific Society for Infectious Diseases
Publications
Over 100 articles and abstracts in leading national and international
journals. Author and coauthor of the national regulatory documents and
education materials for specialists.
PAVEL O. BOGOMOLOV
POSITION TITLE: Deputy Chief of Clinical and Diagnostic Work of the State
Budgetary Healthcare Institution of Moscow Area Moscows regional research
clinical institute n.a. M.F. Vladimirskiy (MONIKI) ,61/2 Schepkin str., 129110
Moscow, Russia
POSITIONS AND EMPLOYMENT:
2014 p.d. Deputy Chief of the Clinical and Diagnostic Work of the State
Budgetary Healthcare Institution of Moscow Area Moscows
regional esearch clinical institute n.a. M.F. Vladimirskiy
2012 2014 Physician Clinical Hospital of Tsentrosoyuz, 57,
Gilyarovskiy str., Moscow Russia
2010 2012 Senior staff scientist of Laboratory of Clinical Pharmacology
and Anti-dote test - Scientific and Practical Center of Sports
Medicine, Zemlyanoy Val str., 53 Moscow Russia
2005 2014 Gastroenterologist 7th Central Military Clinical Aviation
Hospital Department of Defense of Russian Federation,
Department of gastroenterology with room of functional
diagnostics in gastroenterology, 17 Prosek Poperechniy
Moscow 107014
2004 present date The head of Hepatology department, Moscow Regional
Scientific and Research Clinical Institute n. a. Vladimirskiy M.F., 61/2
Shepkin str., Moscow Russia 129110
2001 2004 Senior staff scientist of Gastroenterology Department,
Moscow Regional Scientific and Research Clinical Institute n. a.
Vladimirskiy M.F., 61/2 Shepkin str., Moscow Russia 129110
1999 2001 Resident, Clinical residency in Central Research Institute of
Gastroenterology, 86 Enthusiastov highway, Moscow 111123
1998 1999 General Practitioner, City clinical hospital # 50, Department of
internal diseases, 21 Vuchetich str., Moscow 125206
OTHER EXPERIENCE AND PROFESSIONAL MEMBERSHIPS:
2006 Russian Society of liver study
2004 Russian Gastroenterology Association member

RESEARCH EXPERIENCE:
Primary Investigator in Phase III, HBV, 2002 2005 (3 studies); phase III,
HCV, 2004 2006; phase II, 2005 2006. Phase IV, HCV, 2004; phase II, Liver
cirrhosis, 2006; phase II, HCV, 2009, 2010, Phase Ia/IIb, III, IV, HCV,2012 p.d.
39
DAVID METREVELI
MD PhD
Education:
19841990: State Medical University, Tbilisi, Georgia.
19901991: Post-diploma training in the field of Pediatrics.
1992 and 1996: Post-diploma Training in the field of infectious diseases.
Post-diploma Training Institute for Physicians. Tbilisi, Georgia.
2000: Training course for Hepatology and Gastroenterology. Hospital of
University, Freiburg, Germany.
2013: Training course for Hepatology. Liver Unit at Hospital General
Universitario Valle Hebron, Barcelona, Spain.
In 1999 has been awarded PhD. degree (Medical sciences).
Publications: 31 scientific papers and articles.
Employment History: 19901993: Infectious Diseases, AIDS and Clinical
Immunology Research Center.
Position: Physician-Infectionist;
1993-2012: Department of Plasmapheresis and Intensive therapy.
Position: Head of the department.
From 2012: Medical Center Mrcheveli, Hepatology and Gastroenterology
Department. Position: Head of the department.
The study enrolled:
1. ML 25544 Prospective observational study on predictors of on-treatment
response and sustained virological response in cohort of HCV-infected patients
treated with pegylated interferons in Georgia; Position: Principal Investigator;
2011 2014;
2. Study number: 013012cRPh. Phase: I An open label, parallel design study
to assess the pharmacokinetics of Narlaprevir 200 mg as a single oral dose and
in combination with Ritonavir 100 mg in patients with hepatic impairment and
healthy matched volunteers. Position: Scientific consultant; 2013 2014.
Membership in Professional Societies: Member of Georgian Society of
Infectionists from 1992; Member of Georgian Hepatology Association (GHA) from
2000; At present President of GHA. Member of EASL from 2006.
ALEXANDER V. NERSESOV
MD, ScD, Professor of Medicine National Research Institute of Cardiology
and Internal Medicine, Almaty, Kazakhstan
Professor Nersesov is currently Head of the Department and Chair of
Gastroenterology, Hepatology and Endoscopy at the National Research
Institute of Cardiology and Internal Medicine, Almaty, Kazakhstan. He studied
medicine at the Kazakh State Medical University and completed residency in
internal medicine. Then Dr Nersesov went on to specialize in gastroenterology
and immunology receiving his academic degrees of Candidate in Medical
Sciences (1992), Doctor in Medical Sciences (1999), and academic ranks of
Associate Professor and Full Professor (2003). Throughout his career Professor
Nersesov has held professional appointment from Research Fellow (1992),
Senior Research Fellow (1995) in the sequel and Head (2000) of the Clinical
Department at the Research Center of Nutrition, Almaty, Kazakhstan to more
recently Professor of Internal Medicine at the Kazakh State Medical Academy,
Astana, Kazakhstan (20012008). Between 2001 and 2008 Professor Nersesov
combined his academic career with state service at the Ministry of Health of
the Republic of Kazakhstan as the Director of Medical Care and Prevention
and the Counsellor for the Minister. In 2009 he moved to Japan where he
spent a further year as a Visiting Fellow in Hepatology at the National Health
Organization Nagasaki Medical Center. On returning to Kazakhstan, Professor
Nersesov started working for the National Research Institute of Cardiology and
Internal Medicine as a Head of Department of Gastroenterology and Hepatology
(since 2009) and Chair of Gastroenterology, Hepatology and Endoscopy (since
2012). Professor Nersesov has professional affiliations with several professional
organizations including European Association for the Study of the Liver (EASL),
American Association for the Study of Liver Diseases (AASLD), Asian Pacific
Association for the Study of the Liver (APASL). Since 2007 he is been serving
as the President of the Kazakh Association for the Study of the Liver (KASL).
Professor Nersesovs main clinical and research interests are in chronic
viral hepatitis and liver cirrhosis complications. He is author and co-author
approximately 110 publications in local and international journals, provides
clinical supervision, serves as a principal investigator in clinical trials and the
main organizer of local and international conferences on gastroenterology and
hepatology in Kazakhstan.
41
IULIANNA LUPASCO
Head of Scientific Laboratory of Gastroenterology, MD, associate professor in
gastroenterology, hepatology. Chisinau. Republic of Molodva.
Profile: Administrative professional support offering versatile management
skills and proficiency in creating, planning and fulfillment of scientific projects
in gastroenterology and hepatology field, assessment of risk factors of chronic
diffuse liver diseases development and progression, improvement of diagnostic
and therapy protocols of CDLD and GT, clinical-practical implementation of
patents and innovations. Strong planner and problem solver who readily adapts
to change, works with team and exceeds expectations. Able to juggle multiple
priorities and meet tight deadlines without compromising quality.
Education: State Univeristy Of Medicine And Pharmacy N.Testemitanu,
Chisinau, Republic Of Molodva, Diploma with distinction
961467, June 26 1987
Professional Development: PhD thesis in medical sciences 14.00.05
Internal Diseases Interrelation of exocrine end
endocrine function of the pancreas and
chronic hepatitis DH Diploma 14.93.32,
November 29, 2000
19872009: working in Central Republic Hospital (physician,
gastroenterologist)
19982006 (SUMP N.Testemitanu part time: junior researcher, superior
scientific researcher)
2006 (SUMP N.Testemitanu part time: associate professor)
Certificate awarding higher category as gastroenterologist, no.95 / p.4 untill
2007
20092012: superior scientific researcher, Laboratory of Gastroenterology
Certificate awarding higher category as gastroenterologist, no.95 / p.4 untill
2012
Certificate awarding higher category as gastroenterologist no. 1336 untill
2017
2012 present: Head of Laboratory of Gastroenterology
Experience Projects participation: From 2001 till present participated in 8
different International, National, institutional, fundamental, applicative projects on
the hepatology field as an executive researcher
2015-prezent. Chronic diffuse liver diseases extrahepatic manifestations
Institutional, National, Applicative. Executive Senior Researcher
Patents: Holder of 7 patents; More than 20 innovations
Membership: Society of Gastroenterologists, Romania from 1994

Romanian Association for the Study of Liver from 1995
Association of Russian Gastroenterology from 1995;
Association of Hepatology and Gastroenterology HEPATEG RM from 2000
Corresponding Member of the International Academy of Ecology and
Protection of Life in Russia (IALPS) from 2006
European Association for the Study of the Liver (EASL) from 2009,
Society of Internal Medicine, RM from 2009
Member of the International Society of Homotoxicology and Homeopathy
(ISOHH)2012-2015 (winded up recently),
Member of the Association of people affected by liver and gastrointestinal
diseases HEPAVIT from 2013, holding the post of President of the
Scientific Committee,
Awards: Awarded with the Medal of Hippocrates by the International Academy of
Ecology and Life Protection in Russia (IALPS) 16.02.2006
Congresses participation: During the last 5 years participated in over 20
congresses, conferences and scientific seminars in
gastroenterology and hepatology on the national
and international levels.
Publications Over 200 publications.
43
IGOR A.KARPOV
19741980 State Medical Institute in Minsk, Medical Faculty;
19801981 Intern graduate course at the Clinical Hospital 4 (therapy);
19821985 Resident of the department of Infectious Diseases at Minsk
Medical Institute;
2004 Membership ESCMID
2005 Membership ISC
2006 Membership SIDA
2009 Member of European Medical Academy of HIV
2010 Member of Infectious Diseases Society of America
2000 Doctor of Medicine;
2001 Main Specialist of Ministry for Infectious Diseases
2003 Professor
SCIENTIFIC INTERESTS:
The problem of HIV infection and AIDS, Viral hepatitis. Bacterial Sepsis and
Meningitis.
Author of 350 scientific works.
LARISA V. MOROZ
MD, Professor
Moroz Larisa Vasilivna, MD, Professor, Head of the Infectious Diseases
Department of the National Pirogov Memorial Medical University, Vinnitsa,
Ukraine. Head of the Hepatological Centre of the Vinnitsa city municipal hospital
#1. Author of more than 250 scientific publications, scientific adviser of eleven
PhD thesiss, and two doctoral thesis. The main scientific activities are chronic
viral hepatitis and HIV infection.
LOCAL
SPEAKERS
45
GAYANE MELIK-ANDREASYAN
MD, PhD, ScD, Professor
CURRENT POSITION
Director, The Research Institute of Epidemiology, Virology and Medical
Parasitology after A.B.Alexanian MOH RA, Yerevan, Armenia
Gayane G.Melik-Andreasyan graduated from General Medicine faculty the
Yerevan State Medical Institute in 1977 with diploma of Honor. In 19771980
studied the post-graduate fellowship programme in the field of Virology at
the Ivanovsky Institute of Virology, Moscow, Russia. In 1981 she got a PhD
degree at Ivanovsky Institute of Virology, Moscow, Russia and in 2004 Doctor
of Medical Sciences (ScD) degree. She studied the intership progamme in
laboratory diagnostics at the Pasteur Institute, Paris, France and in laboratory
center Foundation Merieux, Lyon, France.
Since 1980 Gayane Melik-Andreasyan has worked in the Research Institute
of Epidemiology, Virology and Medical Parasitology after A.B.Alexanian MOH
RA, in 2007 was elected as a Director of Institute.
Current research interests of professor Melik-Andreasyan are: Epidemiology
of Infectious Diseases, Laboratory diagnosis of Viral and Bacterial Infection,
Investigation of Humoral Immunity against Infectious Diseases and Vaccination,
biological quality of infectious agents, Prevention and Management of Viral
Hepatitis and other Infectious Diseases.
Professor Melik-Andreasyan skillfully combines the research and teaching
activities. She provides teaching cours on epidemiology and virology for
students, residents of all medical specialties and traning course on TADR
Epidemiology (DETRA Program). She has supervised numerous PhD thesises.
She is an author of more than 210 scientific articles, abstracts and the national
regulatory documents and educational material for specialists.
Gayane Melik-Andreasyan is a member of editional board of journal In world
of Viral Hepatitis (Moskow, Russia), Asian Pacific Association for the Study of
the Liver (APASL), Armenian Hepatological forum, Armenian.
GAYANE SAHAKYAN
M.D.
National Immunization Program Manager of Republic of Armenia since
September, 2006. Since January, 2014 Advisor to the Director General of
the National Center of Disease Control and Prevention of Ministry of Health
of Armenia. Member of Governing Consul of the International Association of
Immunization Managers since 2013, member of IRC (Independent Review
Committee) of GAVI since 2014.
Has participated in various International meetings and forums for
immunizations and immunization advocacy. Regularly has conducted workshops
on immunization practices, VPD Surveillance and vaccine safety for Health Care
workers.
47
HASMIK GHAZINYAN
MD, PhD
HEAD OF HEPATOLOGY DEPARTMENT OF NORK
CLINICAL HOSPITAL OF INFECTIOUS DISEASES
Ghazinyan Hasmik L. is one of the Armenian leader experts in the field
ofHepatology.
She is actively participating in National Research Studies aimed at
investigations and improvement of liver health in Armenia.
Ghazinyan Hasmik L. graduated from Yerevan State Medical Institute in 1978
with Diploma of Honor and continued her fellowship program as a hepatologist
locally and abroad, including USA in 1996.
Ghazinyan Hasmik L. is an author of more than 160 scientific publications in
local and international journals.
Dr.Ghazinyan attended more than 220 specialized medical conferences (local
and international) and was invited speaker and moderator in many of them.
Dr.Ghazinyan is:
Member of AARC working group, APASL ACLF. Research Consortium New
Delhi, India
Member of EASL, APASL, IASL, CEVHAP.
She was:
Chairman of 1st International Hepatological Conference in Armenia in 2011
o-chairman of 2nd Biannual International Conference of Armenian
Hepatological Forum in 2013
Co-chairman of 1st Transcaucasian Congress in Georgia in 2014.
Dr.Ghazinyan H.is:
President of Armenian Hepatological Forum.
Head of Department of Infectious Diseases and Epidemiology in Medical
University named after ST.Tereza.
Member of Editorial Advisory council of scientific-practical journal Blood
Armenia
Member of Editorial Advisory council of scientific practical journal Actual
Infectology, Ukraine.
Author of Methodical Recommendations: Management of HBV and HCV
Infections in Onco/Oncoheamatological Patients in the Republic of Armenia
Dr.Ghazinyan is a chairman of STC of APASL on HBV in Yerevan, Armenia,
in October 2015.
TIGRAN DAVTYAN
Education (degrees, dates, universities)
2003 Doctor of Biological Sciences (ScD). Field: Molecular Biology
1993 Candidate of Biological Sciences (Ph.D); Field: Genetics and
Immunology
19891992 Ph.D. student, Laboratory of Genetic Mechanisms of Cell
Malignization And Differentiation, Institute of Cytology,
St. Petersburg, Russia.
19831988 Yerevan State Medical University, Faculty of Pharmacy
Career/Employment (employers, positions and dates)
2011 up to present Director of Analytical Laboratory of Scientific Centre of
Drug and Medical Thechnology Experttise JSC
19992011 Head of HIV-Clinical Trail Laboratory of the ARMENICUM
Research Center, Yerevan, Rep. of Armenia.
19982006 Consultant on Science, Laboratory of Immunology, The Second
Clinical Hospital of the Yerevan State Medical University, Rep.
of Armenia.
1998 up to present Senior Research Scientist, Laboratory of
Neurohormones Biochemistry, H. Buniatian Institute of
Biochemistry, Natl. Acad. Sci. of Armenia.
20022005 Teaching Assistant in the Department of Diagnostics, National
Institute of Health, Ministry of Health of the Republic of Armenia
19882003 Senior Researcher, Laboratory of Immunology, Institute of
Epidemiology, Ministry of Health of the Republic of Armenia
19891992 Research Scientist, Laboratory of Genetic Mechanisms of Cell
Malignization and Differentiation, Institute of Cytology,
St. Petersburg, Russia.
19881989 Senior technician in the Laboratory of Molecular and Cellular
Immunology, Institute of Molecular Biology, Natl. Acad. Sci. of
the Rep. of Armenia.
49
VIOLETA SARGSYAN
MD, PhD
HEAD OF CLINICAL SERVICES
CLINICAL CENTRE ARMENICUM
Violeta Sargsyan is one of the leading experts in the field of hepatology and
infectious pathology. She skillfully combines the clinical practice with scientific
and research work, especially in the sphere of Hepatology and HIV infection.
Violeta Sargsyan is actively engaged in the study and development of new
drugs. From the first day of Clinical Center Armenicum establishment she was
a researcher in many clinical trials, later served as adviser (monitor) in different
countries worldwide.
From 2002 to 2005 being as a monitor, she led the independent clinical
research on the Efficacy, Safety and Tolerability of the medicine Armenicum
among HIV-infected patients at Clinical Hospital after Botkin N30 in St.
Petersburg and AIDS Center in Moscow.
Dr. Sargsyan is actively participating in many annual international
conferences on diseases of the liver (EASL, APASL, AASLD) and monothematic
conferences in different countries: Italy, Spain, Japan, Holland, Singapore and
Thailand.
She is the author of more than 80 scientific publications and poster papers
which are published in both national and international journals. Besides Dr.
Sargsyan is the author of 3 methodological guidelines for physicians.
V. Sargsyan graduated from Yerevan State Medical University (YSMU) in
1988 with honor. Since 1993 Violeta has been working as a deputy chief doctor
of medical infections at #1 Infectious Hospital, simultaneously teaching at YSMU
as a professor of infectious diseases department.
In 2005 she defended her PhD thesis in St. Petersburg which was devoted
to The phospholipid spectrum and lipid peroxidation in acute hepatitis B and
chronic hepatitis C. As a result she received the degree of candidate of medical
sciences of the Russian Federation.
Currently Violeta Sargsyan works as the head of clinical services at
Armenicum Clinical Center. Dr. Sargsyan is a member of APASL and Armenian
Hepatological Forum and is actively participating in organizational matters of the
forum.
NARINA SARGSYANTS
MD, PhD
INFECTIOUS DISEASE SPECIALIST
DEPARTMENT OF INFECTIOUS DISEASES,
ARMENICUM CLINICAL CENTER
Sargsyants Narina Constantin is one of the leading hepatologists in Armenia.
She graduated from the YSMU in 1996 and continued her specialization
in Residency in field of Infectious Diseases. From 1999 up to 2010 she was
teaching at Department of Infectious Diseases YSMU.
Several Observerships in Hepatology/Gastroenterology and Infectious
Diseases Departments in leading European Hospitals: France (CHU de Bictre,
Paris), Austria (AKH, Vienna; SALK, Salzburg), Spain (Hospital Universitario
Virgen Macarena, Seville) and Italy (Universit Cattolica, Rome).
Narina Sargisyants is an author of more than 118 scientific publications (40 in
English) and 17 poster presentations in international conferences (EASL, APASL,
IAS, ISHEAD, ISVHLD, IUSTI, DICID etc.). Topic of her PhD research was
Clinical, epidemiological peculiarities and results of treatment with Pegylated
interferon-alpha 2a and Ribavirin of chronic viral hepatitis C in Armenia.
Dr. Sargisyants is an active participant of multiple local and International
conferences, seminars. She is a member of Armenian Hepatological Forum,
APASL and ISID.
Narina Sargisyants is a member of Editorial Board of World Journal of
Hepatology.
51
NOTES

Conference: Focus On The Hepatitis B Virus

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Conference: Focus On The Hepatitis B Virus

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ASIAN PACIFIC ASSOCIATION FOR THE

STUDY OF THE LIVER

Session 1 HBV: Overview of Epidemiology and Burden of

The Changing Epidemiology of HBV in Asia

The Changing Epidemiology of HBV in Mongolia

The Changing Epidemiology of HBV in Europe

The Changing Epidemiology of HBV in North America

Epidemiology of HBV Infection in CIS countries

Epidemiology of HBV Infection in Russia

Epidemiology of HBV Infection in Ukraine

Epidemiology of HBV Infection in Belarus

Epidemiology of HBV Infection in Georgia

Epidemiology of HBV Infection in Moldova

Epidemiology of HBV Infection in Kazakhstan

Epidemiology of HBV Infection in Armenia

Session 2 - VIROLOGY AND IMMUNOPATHOGENESIS

Covalently Closeed Circular (ccc) DNA is the only reason,

HBV Genotypes and Core and Pre-core Mutations

Interactions Between HBV, Host Immunity and the liver

Session 3 - NATURAL HISTORY

Natural History of Chronic Hepatitis B and

Occult HBV Infection: Clinical Significance

Acute - on - Chronic liver failure (ACLF)

The Role of Non-invasive Markers and Imaging in

SESSION 4 - TREATMENT INDICATIONS AND OPTIONS

HBV: Treatment Indications and Therapeutic End-points

Is Clearance of HBsAg and cccDNA a Realistic Target?

First Day Closing

SESSION 5 - CURRENT TREATMENT FOR CHB

Treatment of Patients with CHB with Pegylated Interferon:

NAs as First-line Therapy for CHB

Monitoring and Management of NAs failures

Risk factors of HCC during nucleic acid

Management of CHB patients with Decompensated Cirrhosis

Can Cirrhosis be Really Reversed? A focus on the

SESSION 6 - CHB in SPECIAL POPULATIONS

Management of CHB in the Immunosuppressed Patients

Management of CHB in Children

Management of CHB in Pregnancy

Management of CHB in Co-infected Patients (HBV - HCV ),

Management of CHB in Renal Disease and Renal

SESSION 7 INTERACTIVE CASE STUDY DISCUSSIONS

Case-Based_Management HBV reactivation

UNUSUAL CASE OF HIGHLY REPLICATIVE HBV VIRUS

Hepatitis B reactivation after pagylated interferon

Case of HBV related chronic liver disease presenting

Managment of chronic Hepatitis D

SESSION 8 - WHAT IS ON THE HORISON FOR

Treatment of HBV Beyond the Guidelines

Other New Therapies

Myrcludex B, an NTCP- specific Inhibitor of HBV

Immune Based Therapies for CHB

DR. SHIV KUMAR SARIN

He is the founding Chief Editor of a prestigious international Journal,

BARJESH CHANDER SHARMA

MANOJ KUMAR SHARMA

SAEED SADIQ HAMID

Dr. Mahtab is member of the APASL Working Parties on hepatitis B, Hepatitis

DIANA ALCANTARA PAYAWAL

15. Core Committee, Guidelines on Colon Cancer Screening, Philippine

PROF GAMAL SHIHA

MAJOR ADMINISTRATIVE RESPONSIBILITIES:

September 2010-Date: Editorial Board, Hepatology