P450 Drug Interaction Table

http://medicine.iupui.edu/clinpharm/ddis/main-table

INDIANA UNIVERSITY (HTTP://WWW.IU.EDU)

Go

(/CLINPHARM)

IU Health | Eskenazi Health

School of Medicine
(http://iuhealth.org/)
(http://www.eskenazihealth.org/)
(http://medicine.iu.edu

Department of Medicine
M
Meeddiicciinnee H
Hoom
mee

A
Abboouutt

P
Prroossppeeccttiivvee FFaaccuullttyy

P
Paattiieennttss

S
Suubbssppeecciiaallttiieess

R
Reesseeaarrcchh

Directory (../..
/directory.aspx)

M
Meeddiiccaall EEdduuccaattiioonn

Clinical Pharmacology
A
Abboouutt
FFaaccuullttyy
((//ddiirreeccttoorryy..aassppxx))
FFeelllloow
wsshhiipp
((//C
CLLIIN
NP
PH
HA
AR
RM
M
//FFEELLLLO
OW
WS
SH
HIIP
P))

P450 Drug Interaction Table

SUBSTRATES
1A2

2B6

2C8

2C9

S
Seem
miinnaarr
((//C
CLLIIN
NP
PH
HA
AR
RM
M
//S
SEEM
MIIN
NA
AR
R))
D
Drruugg
IInntteerraaccttiioonnss
((//C
CLLIIN
NP
PH
HA
AR
RM
M
//D
DD
DIIS
S))
R
Reessoouurrcceess
IIIIP
PM
M ((//IIIIP
PM
M))
N
Neew
wss
((//C
CLLIIN
NP
PH
HA
AR
RM
M
//N
NEEW
WS
S))

C
Coonnttaacctt
IInnffoorrm
maattiioonn
Clinical Pharmacology
Research Institute
(R2), Room 402
950 West Walnut
Street
Indianapolis, IN 46202
Ph: (317) 274-2810
Fax:(317) 274-2704

1 of 4

8/9/16, 9:57 PM

P450 Drug Interaction Table

http://medicine.iupui.edu/clinpharm/ddis/main-table

artemisinin
amodiaquine (/clinpharm
N
NS
SA
AIID
Dss::
bupropion (/clinpharm
/ddis/2C8references#amodiaquineSub)2diclofenac (/clinpharm
/ddis/2B6References#bupropionSub)1
cerivastatin (/clinpharm
/ddis/2C9references#diclofenac
caeine (/clinpharm
cyclophosphamide (/clinpharm
/ddis/2C8references#cerivastatinSub) ibuprofen (/clinpharm
/ddis/1A2references#caeineSub)2
/ddis/2B6References#cyclophosphamideSub)paclitaxel (/clinpharm
/ddis/2C9references#ibuprofen
clomipramine (/clinpharm
efavirenz (/clinpharm
/ddis/2C8references#paclitaxelSub)
lornoxicam (/clinpharm
/ddis/1A2references#clomipramineSub)
/ddis/2B6References#efavirenzSub)1
repaglinide (/clinpharm
/ddis/2C9references#lornoxicam
clozapine (/clinpharm
ifosphamide (/clinpharm
/ddis/2C8references#repaglinideSub) meloxicam (/clinpharm
/ddis/1A2references#clozapineSub)
/ddis/2B6References#ifosphamideSub)
sorafenib (/clinpharm
/ddis/2C9references#meloxicam
cyclobenzaprine (/clinpharm
ketamine
/ddis/2C8references#sorafenibSub)
S-naproxenNor (/clinpharm
torsemide (/clinpharm
/ddis/2C9references#S-naproxe
/ddis/1A2references#cyclobenzaprineSub)meperidine
methadone (/clinpharm
/ddis/2C8references#torsemideSub)
piroxicam (/clinpharm
duloxetine
/ddis/2B6References#methadoneSub)
/ddis/2C9references#piroxicam
estradiol (/clinpharm
nevirapine
suprofen (/clinpharm
/ddis/1A2references#estradiolSub)
propafol
/ddis/2C9references#suprofenS
uvoxamine (/clinpharm
selegiline
/ddis/1A2references#uvoxamineSub)
sorafenib (/clinpharm
O
Orraall H
Hyyppooggllyycceem
miicc A
Aggeennttss::
haloperidol (/clinpharm
/ddis/2B6References#sorafenibSub)
tolbutamide (/clinpharm
/ddis/1A2references#haloperidolSub)
/ddis/2C9references#tolbutami
imipramine N-DeMe (/clinpharm
glipizide (/clinpharm
/ddis/2C9references#glipizideS
/ddis/1A2references#imipramineSub)

amitriptyline (/clinpharm
/ddis/1A2references#amitriptylineSub)

mexiletine (/clinpharm
/ddis/1A2references#mexiletineSub)
nabumetone
naproxen (/clinpharm
/ddis/1A2references#naproxenSub)
olanzapine (/clinpharm
/ddis/1A2references#olanzapineSub)
ondansetron (/clinpharm
/ddis/1A2references#ondansetronSub)
phenacetin (/clinpharm
/ddis/1A2references#phenacetinSub)1
acetaminophen
NAPQI
propranolol (/clinpharm
/ddis/1A2references#propranololSub)
riluzole (/clinpharm
/ddis/1A2references#riluzoleSub)
ropivacaine (/clinpharm
/ddis/1A2references#ropivacaineSub)
tacrine (/clinpharm
/ddis/1A2references#tacrineSub)2
theophylline (/clinpharm
/ddis/1A2references#theophyllineSub)2
tizanidine (/clinpharm
/ddis/1A2references#tizanidineSub)
triamterene
verapamil (/clinpharm
/ddis/1A2references#verapamilSub)
(R)warfarin (/clinpharm
/ddis/1A2references#warfarinSub)
zileuton (/clinpharm
/ddis/1A2references#zileutonSub)
zolmitriptan (/clinpharm
/ddis/1A2references#zolmitriptanSub)

2 of 4

A
Annggiiootteennssiinn IIII B
Blloocckkeerrss::
losartan (/clinpharm
/ddis/2C9references#lorsartanS
irbesartan (/clinpharm
/ddis/2C9references#irbesartan
S
Suullffoonnyylluurreeaass::
glyburide (/clinpharm
/ddis/2C9references#glyburide
glibenclamide (/clinpharm
/ddis/2C9references#glibenclam
glipizide (/clinpharm
/ddis/2C9references#glipizideS
glimepiride (/clinpharm
/ddis/2C9references#glimepirid
tolbutamide (/clinpharm
/ddis/2C9references#tolbutami
amitriptyline (/clinpharm
/ddis/2C9references#amitriptyl
celecoxib (/clinpharm
/ddis/2C9references#celecoxib
uoxetine (/clinpharm
/ddis/2C9references#uoxetine
uvastatin (/clinpharm
/ddis/2C9references#uvastati
glyburide (/clinpharm
/ddis/2C9references#glyburide
nateglinide (/clinpharm
/ddis/2C9references#nateglinid
phenytoin-4-OH2 (/clinpharm
/ddis/2C9references#phenytoin
rosiglitazone (/clinpharm
/ddis/2C9references#rosiglitazo
tamoxifen (/clinpharm
/ddis/2C9references#tamoxifen
torsemide (/clinpharm
/ddis/2C9references#torsemide
valproic acid
S-warfarin (/clinpharm
/ddis/2C9references#S-warfarin
zakirlukast

8/9/16, 9:57 PM

P450 Drug Interaction Table

3 of 4

http://medicine.iupui.edu/clinpharm/ddis/main-table

8/9/16, 9:57 PM

P450 Drug Interaction Table

http://medicine.iupui.edu/clinpharm/ddis/main-table

Information for
Patients (/DMED/PATIENTS)
Referring Physicians (http://www.iuhealth.org)
Prospective Faculty (http://faculty.medicine.iu.edu/)
Faculty & Sta (http://hr.iu.edu/)
Supporters (http://medgifts.iu.edu/makeagift/give-now/)

Quicklinks
D
Diirreeccttoorryy ((....//....//ddiirreeccttoorryy..aassppxx))
Maps & Directions (http://map.iu.edu/iupui/index.php)
Ways of Giving (/dmed/giving/)
P450 Drug Interactions (/clinpharm/ddis/index)
Helpdesk Support (/dmed/helpdesk)
Citrix Login (https://citrix.medicinedept.iu.edu/Citrix/XenApp/auth/login.aspx)|MDEP Intranet (https://portal.medicinedept.iu.edu/)
Login (../../Login.aspx) | Webmaster (mailto:mdepweb@iupui.edu) | Request (mailto:IN-MDEP-WEBUPDATES@exchange.iu.edu)

Medicine News
Study nds hundreds of genes and
genetic codes that regulate genes tied
to alcoholism
(http://news.medicine.iu.edu/releases
/2016/07/rats-geneticsalcoholism.shtml)

Contact Us
Clinical Pharmacology
Research Institute (R2), Room 402
950 West Walnut Street
Indianapolis, IN 46202
Ph: (317) 274-2810
Fax:(317) 274-2704

Researchers seek volunteers for study

of Facebook app for Alzheimer's
caregivers (http://news.iupui.edu
/releases/2016/08/socialwork-facebook-app-alzheimers.shtml)
Cell lines developed at IU School of
Medicine licensed to Canadian life
sciences company (http://news.iu.edu
/releases/2016/07/iurtc-licensesdu-yan-cells.shtml)

FULFILLING

the

PROMISE

Privacy Notice (http://medicine.iu.edu/privacypolicy/)

(http://www.iu.edu/)

Copyright (http://www.iu.edu/copyright/index.shtml) 2015 The Trustees of Indiana University (http://www.iu.edu/),

Copyright Complaints (http://www.iu.edu/copyright/complaints.shtml)

4 of 4

8/9/16, 9:57 PM