H: Chapter 321, 332

R: Chapter 26
GG: Chapter 34
Osteoarthritis (FA13 p390) (FA14 p424) (SU14 p234)
Treatments
-- Acetaminophen (FA13 p405) (FA14 p440) (SU14 p245)
-- NSAIDs (FA13 p404) (FA14 p440) (SU14 p245-246) (H p2835, Table 332-1)
-- COX-2 inhibitors (FA13 p405) (FA14 p440) (SU14 p246-247)
-- Aspirin (FA13 p404) (FA14 p439) (SU14 p246)
Rheumatoid arthritis (FA13 p390) (FA14 p424) (SU14 p234)

3 Question Warm-Up

1. What effect will a noncompetitive antagonist have on Vmax and Km? (FA13 p229)
(FA14 p242) (SU14 p12-13)

OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS

OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS

2. What effect will a competitive antagonist have on efficacy and potency?

(FA13 p229) (FA14 p242) (SU14 p15)

3. An 80-year-old man presents with a systolic crescendo-decrescendo murmur.

What is the most likely cause? (FA13 p259) (FA14 p273) (SU14 p91)

RHEUM AND DERM

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OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS

End of Session Quiz

4. What is the classic feature of osteoarthritis? (FA13 p390) (FA14 p424) (SU14 p234)

5. What two antibodies are most useful in diagnosing rheumatoid arthritis?

6. By what mechanism do NSAIDs cause renal disease? (FA13 p405) (FA14 p440)

Rapid-Fire Facts
Swollen, hard, painful finger joints
Swollen, boggy, painful finger joints
Cartilage erosion with polished bone
beneath

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