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  • GIT Regulators, Antiflatulents & Anti-Inflammatories Antiemetics See Available Brands of Metoclopramide

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    Prisca Wicita
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    This document provides information on the indications, dosages, and administration of metoclopramide. It is indicated for diabetic gastric stasis in adults at 10 mg 4 times per day for 2-8 weeks. The dosage should be reduced by at least 50% for those with moderate to severe renal impairment depending on creatinine clearance. It is also indicated for nausea and vomiting associated with cancer chemotherapy or radiotherapy, with dosages ranging from 100 mcg/kg to 12 mg/kg per day depending on age. Dosage reduction may be necessary for those with hepatic impairment.

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    This document provides information on the indications, dosages, and administration of metoclopramide. It is indicated for diabetic gastric stasis in adults at 10 mg 4 times per day for 2-8 weeks. The dosage should be reduced by at least 50% for those with moderate to severe renal impairment depending on creatinine clearance. It is also indicated for nausea and vomiting associated with cancer chemotherapy or radiotherapy, with dosages ranging from 100 mcg/kg to 12 mg/kg per day depending on age. Dosage reduction may be necessary for those with hepatic impairment.

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    © All Rights Reserved
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    14 views7 pages

    GIT Regulators, Antiflatulents & Anti-Inflammatories Antiemetics See Available Brands of Metoclopramide

    Uploaded by

    Prisca Wicita
    This document provides information on the indications, dosages, and administration of metoclopramide. It is indicated for diabetic gastric stasis in adults at 10 mg 4 times per day for 2-8 weeks. The dosage should be reduced by at least 50% for those with moderate to severe renal impairment depending on creatinine clearance. It is also indicated for nausea and vomiting associated with cancer chemotherapy or radiotherapy, with dosages ranging from 100 mcg/kg to 12 mg/kg per day depending on age. Dosage reduction may be necessary for those with hepatic impairment.

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    © All Rights Reserved
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    of 7

    metoclopramide

    MIMS Class : GIT Regulators, Antiflatulents & Anti-inflammatories, Antiemetics


    See available brands of metoclopramide

    See related metoclopramide information

    Indication &
    Dosage

    Oral
    Diabetic gastric stasis
    Adult: 10 mg 4 times/day. To be given 30 minutes before
    meals and at bedtime. Usual treatment duration: 2-8 wk.
    Renal impairment: Moderate to severe: Reduce dose by
    at least 50%
    CrCl (ml/min) Dosage Recommendation
    <40

    Reduce dose by at least 50%.

    Hepatic impairment: Dose reduction may be necessary.


    Oral
    Nausea and vomiting associated with cancer
    chemotherapy or radiotherapy
    Adult: 2 mg/kg/dose, given 1 hr before start of treatment.
    Repeat dose 3 times at 2-hrly intervals. May repeat 2
    additional doses at 3-hrly intervals if needed. Max: 12
    mg/kg/day.
    Child: Neonate: 100 mcg/kg every 6-8 hr; 1 mth-1 yr (up
    to 10 kg): 100 mcg/kg (max 1 mg) bid; 1-3 yr (10-14 kg): 1
    mg bid-tid; 3-5 yr (15-19 kg): 2 mg bid-tid; 5-9 yr (20-29
    kg): 2.5 mg tid; 9-14 yr (30 kg): 5 mg tid; 15-19 yr (30-59

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