Hyperthyroidism

Decreased TSH and increased T4

Most common form is graves disease
o Other causes include toxic nodular goiter, thyroiditis,
excess Iodine intake, pituitary tumors, and thyroid cancer
Thyrotoxicosis
o Clinical syndrome of hypermetabolism from excess T4/3
o Happens when someone with hyperthyroidism is exposed
to stressors
o Most prone is thyroidectomy
o CM
Tachycardia
HF
Shock
Hyperthermia
Restless
Irritable
Seizures
Abdominal pain
Vomiting
Delirium/coma
Graves disease
o Patient develops antibodies to the TSH receptor and they
attatch and stimulate the tyroid gland to release T3/4
o Remissions and exacerbations
o Goiter on palpation of thyroid gland
Auscultation bruits
Opthalmopathy is eye appearance and exopathalmos
is protrusion of eyes
Increased fat and fluid
o s/s
clubbing, palpitations tremors weight loss acropachy
Drug therapy
o PTU and methimazole are first line therapy