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  • Waktu (Jam) CP (Ug/ml) LN CP KEL R LN CP' CP'

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    Erwin
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    This document contains data from an experiment measuring concentration (Cp) of a drug over time. It includes the time, concentration, natural log of concentration, area under the curve (AUC), and fraction absorbed (Fab) calculated at each time point. A linear regression was performed on AUC vs time with an R^2 value of 0.9664798497.

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    biofar

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    This document contains data from an experiment measuring concentration (Cp) of a drug over time. It includes the time, concentration, natural log of concentration, area under the curve (AUC), and fraction absorbed (Fab) calculated at each time point. A linear regression was performed on AUC vs time with an R^2 value of 0.9664798497.

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    © All Rights Reserved
    Download as XLSX, PDF, TXT or read online from Scribd
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    3 views5 pages

    Waktu (Jam) CP (Ug/ml) LN CP KEL R LN CP' CP'

    Uploaded by

    Erwin
    This document contains data from an experiment measuring concentration (Cp) of a drug over time. It includes the time, concentration, natural log of concentration, area under the curve (AUC), and fraction absorbed (Fab) calculated at each time point. A linear regression was performed on AUC vs time with an R^2 value of 0.9664798497.

    Copyright:

    © All Rights Reserved
    Download as XLSX, PDF, TXT or read online from Scribd
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    of 5

    Waktu (jam)

    Cp(ug/ml) ln cp
    KEL
    R
    LN
    0
    0
    1
    3.13 1.141033
    2
    4.93 1.595339
    3
    5.86 1.76815
    4
    6.25 1.832581
    5
    6.28 1.83737
    6
    6.11 1.809927
    7
    5.81 1.759581
    8
    5.45 1.695616
    9
    5.06 1.621366
    10
    4.66 1.539015
    12
    3.9 1.360977
    14
    3.24 1.175573
    16
    2.67 0.982078
    18
    2.19 0.783902
    24
    1.2 0.182322
    28
    0.81 -0.21072
    32
    0.54 -0.61619 -0.10571 -0.999948
    36
    0.36 -1.02165
    48
    0.1 -2.30259

    2.669
    2.564
    2.459
    2.354
    2.249
    2.144
    2.039
    1.934
    1.829
    1.724
    1.514
    1.304
    1.094
    0.884
    0.254
    -0.166
    -0.586
    -1.006
    -2.266

    Cp'
    14.42554
    12.98766
    11.69311
    10.5276
    9.478253
    8.533503
    7.682922
    6.917123
    6.227656
    5.606911
    4.544874
    3.684003
    2.986195
    2.420563
    1.289172
    0.847046
    0.556549
    0.365679
    0.103726

    -0.5

    1
    Column C

    0
    -1

    Cp'

    10

    20

    30

    40

    50

    60

    -1
    -1.5

    -2

    -2

    -3

    -2.5

    3
    2.5
    f(x) = - 0.1001718353x + 2.4349423853
    Column I
    R = 0.9664798497
    Linear (Column I)

    2
    1.5

    Linear (Column I)

    Linear (Column I)

    0.5
    0
    0

    10

    15

    20

    25

    30

    30 32 34 36 38 40 42 44 46 48 50

    f(x) = - 0.1057102159x + 2.77398752


    Colum
    R = 0.9998966254
    Linea

    Cp'-LN Cp' Ln Delta


    11.7565364
    10.4236642
    9.23411258
    8.173596
    7.22925284
    6.38950347
    5.64392243
    4.98312347
    4.39865589
    3.88291131
    3.03087398
    2.38000325
    1.89219499
    1.53656262
    1.0351718
    1.01304623
    1.14254903
    1.37167877
    2.36972626

    Ka

    2.4644094 0.100172
    2.3440786
    2.2229045
    2.100909
    1.9781357
    1.8546566
    1.7305793
    1.6060569
    1.481299
    1.3565852
    1.108851
    0.8671019
    0.6377375
    0.4295479
    0.0345674
    0.0129619

    40 42 44 46 48 50

    .1057102159x + 2.7739875234
    Column C
    98966254
    Linear (Column C)

    ln cp

    kel

    1.141033
    1.595339
    1.76815
    1.832581
    1.83737
    1.809927
    1.759581
    1.695616
    1.621366
    1.539015
    1.360977
    1.175573
    0.982078
    0.783902
    0.182322
    -0.210721
    -0.616186 -0.10571
    -1.021651
    -2.302585

    AUC t-1 -t
    1.565
    4.03
    5.395
    6.055
    6.265
    6.195
    5.96
    5.63
    5.255
    4.86
    8.56
    7.14
    5.91
    4.86
    10.17
    4.02
    2.7
    1.8
    2.76

    AUC 0-t
    0
    1.565
    5.595
    10.99
    17.045
    23.31
    29.505
    35.465
    41.095
    46.35
    51.21
    59.77
    66.91
    72.82
    77.68
    87.85
    91.87
    94.57
    96.37
    99.13

    AUC 0 sampai t tak terhingga


    0.9460737938

    AUC 0 sampai tak terhingga cp+k [AUC] 0-t Fab (Fraksi Obat yg terabsorbsi)
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938
    100.0760737938

    3.2954205
    5.5213915
    7.021643
    8.0516565
    8.743867
    9.2286785
    9.5586505
    9.7937415
    9.959195
    10.072897
    10.217689
    10.312387
    10.367074
    10.400776
    10.485745
    10.520659
    10.536049
    10.546309
    10.578041

    0.3115341016
    0.5219673
    0.6637942697
    0.7611670724
    0.8266055123
    0.8724373918
    0.9036314474
    0.9258558839
    0.9414971071
    0.9522459782
    0.965933957
    0.9748862762
    0.980056137
    0.9832421712
    0.9912747549
    0.9945753661
    0.9960302669
    0.9970002007
    1

    FTA
    0.688466
    0.478033
    0.336206
    0.238833
    0.173394
    0.127563
    0.096369
    0.074144
    0.058503
    0.047754
    0.034066
    0.025114
    0.019944
    0.016758
    0.008725
    0.005425
    0.00397
    0.003
    0

    ln FTA

    k abs

    -0.373289 0.175169
    -0.738076
    -1.090032
    -1.431991
    -1.752186
    -2.059148
    -2.339575
    -2.601745
    -2.838679
    -3.041692
    -3.379454
    -3.684341
    -3.914834
    -4.08889
    -4.741535
    -5.216805

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