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10.1007@s11154 016 9374 Z
10.1007@s11154 016 9374 Z
1007/s11154-016-9374-z
& Aikaterini
Liakou
& Christos
C.
1 Introduction
The majority of consumers tightly associate good health
with nutrition and skin quality. Apparently, most of them
also
* Apostolos Pappas
apappas@its.jnj.com
4 Mechanisms of incorporation
The mechanisms that lead to the incorporation of
micronutrients such as carotenoids into the skin or the
needed doses from servings of fruits and vegetables are
unknown. Therefore, future studies are needed to decode
this and, in parallel, elaborate on the benefit that
ingestion of fruits and vegetables has for the skin. It is
known that these are the primary dietary sources that
contain these bioactive agents, which not only protect
plants against solar UV damage but also play a
significant role in the photoprotection of skin, which has
5 Topical application
6.2 Acne
Vitamin A and its natural metabolites have been
approved for topical and systemic treatment of mild,
moderate, and severe, recalcitrant acne as well as
photoaging and biological skin aging [59].
The association between acne disease and nutrition
has been highly controversial. The low glycemic load
diet resulted in a significant reduction in weight, body
mass index, and free androgen index and increased
insulin-like growth factor binding protein-1 (IGFBP-1)
serum levels coupled with reduced bioavailability of
free IGF-1 and improved insulin sensitivity. High glyce-
7 Conclusion
A number of clinical studies have shown the firm
relationship between nutrition and cutaneous
physiology and pathophysiology, but a lot of unknown
topics need to be further investigated.
Compliance with ethical standards
Conflict of interest The authors declare that they have no conflict
of interest.
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