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Running Head: Adrenal Insufficiency 1
Running Head: Adrenal Insufficiency 1
Adrenal insufficiency
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Date:
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Adrenal insufficiency 2
caused by dysfunction of the adrenal cortex. The adrenal cortex produces 3 steroid hormones
namely glucocorticoids, mineralocorticoids and androgens which are important in acute adrenal
insufficiency occurs when these hormonal effects are reversed other glands fail to release the
adequate amounts of hormones to meet the bodys physiologic needs. According to studies,
patients with adrenal crisis are at risk of getting infections and severe cases, Bilateral massive
The prevalence of Addison disease is at 4-6% with highest numbers in countries such as
Britain and Denmark. Mortality associated with the condition is always due to delay in diagnosis
and failure to institute adequate replacement and treatment. Death is higher in patients due to
infectious diseases and cardiovascular conditions. The disease is more common in females and
children, in all races and a common presentation in adults aged 30-35 years. Symptoms of the
disease which usually develops slowly over several months include low blood sugar, abdominal
pain, fatigue, hyperpigmentation, weight loss and craving of salt. Addison crisis symptoms
include low blood pressure, severer vomiting and diarrhea, loss of consciousness and high levels
of potassium. it is advisable to seek medical assistance on the onset of these symptoms to prevent
ACTH tests may be provided during resuscitation of the patient and stress doses in
while awaiting ACTH stimulation results. Patients with these symptoms are advised to consult
endocrinologists, infectious disease specialist, cardiologist, critical care physicians and surgeons.
breathing and air circulation and the use of coma protocol such as glucose and thiamine. The
patients mineralocorticoid levels should be maintained and one of the recommended drugs is
telaprevir.