Maximum Daily Dose of Levofloxacin

Levofloxacin Eye drops Solution :

Label Claim/Strength: Each ml Contains Levofloxacin 15.00 mg (1.5% w/v)

Dosage: Instill one to two drops in the affected eye(s) every 30 minutes to 2 hours while awake.
(Ref.: Dailymed Label of IQUIX- levofloxacin solution)

Calculation for Levofloxacin :

Label Claim/mL, LC: 15.00 mg
Maximum amount of Dose in one time, MAD: Two drop
Maximum number of eyes, MNE: 2
Maximum dosing frequency: every 30 minutes (2 times per hour)
Maximum number of dose/day, MND: 2 18 = 36
Maximum Drop Size, MDS: 50 L

Maximum Daily Dose = [(LC x MAD x MNE x MND x MDS)/1000] mg

= [(15 x 2 x 2 x 36 x 50)/1000] mg
= 108 mg

Levofloxacin Tablet :

Label Claim/Strength: Each tablets Contains Levofloxacin 750 mg .

Dosage: The usual dose of LEVAQUIN Tablets 750 mg administered orally every 24 hours.
(Ref.: Dailymed Label of LEVAQUIN - levofloxacin tablet, film coated)

Calculation for Levofloxacin :

Label Claim/tab, LC: 750 mg
Maximum amount of Dose in one time, MAD: one
Maximum dosing frequency: 1 tab every 24 hours
Maximum number of dose/day, MND: 1
Maximum Daily Dose = [(LC x MAD x MND)
= [(750 x 1 x 1)] mg
= 750 mg

Levofloxacin Oral Solution :

Label Claim/Strength: Each ml Contains Levofloxacin 25.00 mg (2.5% w/v)

Dosage: The usual dose of Levofloxacin Oral Solution is 750 mg administered orally every 24 hours.
(Ref.: Dailymed Label of LEVAQUIN- levofloxacin solution)

Maximum Daily Dose = 750 mg