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  • Punya Fadam

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    57-Aditya
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    The document describes the synthesis of sulfatiazol from succinyl sulfanilamide. Sulfanilamide is reacted with succinic anhydride to form succinyl sulfanilamide. This is then reacted with sodium nitrite and hydrochloric acid to form the diazonium salt. Zinc dust is added to reduce the diazonium salt and form sulfatiazol.

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    hahaha

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    The document describes the synthesis of sulfatiazol from succinyl sulfanilamide. Sulfanilamide is reacted with succinic anhydride to form succinyl sulfanilamide. This is then reacted with sodium nitrite and hydrochloric acid to form the diazonium salt. Zinc dust is added to reduce the diazonium salt and form sulfatiazol.

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    © All Rights Reserved
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    8 views1 page

    Punya Fadam

    Uploaded by

    57-Aditya
    The document describes the synthesis of sulfatiazol from succinyl sulfanilamide. Sulfanilamide is reacted with succinic anhydride to form succinyl sulfanilamide. This is then reacted with sodium nitrite and hydrochloric acid to form the diazonium salt. Zinc dust is added to reduce the diazonium salt and form sulfatiazol.

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    © All Rights Reserved
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    of 1

    O

    O
    C OH
    C NH SHO2NH2 H2O/OH
    H2C H2C
    S
    COOH
    COOH
    Asam suksinat
    Suksinil sulfatiazol N
    +

    NH2 SO2NH
    S

    Sulfatiazol N

    HCl
    NH2 SHO2NH2 + HNO2 Cl N+ SO2NH + H2O
    S S
    N

    N Garam diazonium N
    Sulfatiazol

    - N+
    NO2 NH2 Cl N

    (Zn+ HCl) HCl + H2O


    + H2 + HNO2
    reduksi

    HC OH HC OH HC OH

    HC NHCOCHCl2 HC NHCOCHCl2 HC NHCOCHCl2

    CH2OH CH2OH CH2OH

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