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Correlation between the Sputum Bacteriology and Lung Function in

Patients with Stable Bronchiectasis
K. B. Gupta, S. Vishvkarma, A. S. Sandhya, S. Magu, U. Choudhary, M. Gupta

Abstract

Rationale: To study the correlation between the sputum bacteriology and lung function in patients with stable
bronchiectasis.

Materials and Methods: 80 patients suffering from stable bronchiectasis belonging to both the sexes and age
above 14 years were included in study. All patients were assessed clinically with detailed history and thorough
clinical examination. Patients were subjected to assessment of microbiological flora in their sputum. Lung
functions were measured with spirometry and parameters recorded were PEFR in l/min, FEV1 in litres, FVC in
litres, and FEV1/FVC. Sputum samples of +1 and +2 grade were inoculated on blood agar, MacConkey's agar
and chocolate agar at 37C for 48 hours.

Results: P aeruginosa was seen as the most common colonizing bacteria and these patients had de-creased %
predicted FEV1, FVC, FEV1/FVC and PEFR with mean values of 43.6114.6, 51.8716.8, 79.8314.6,
42.1714.6 respectively as compared to patients of non P aeruginosa group. The % predicted FEV1, FVC,
FEV1/FVC and PEFR in non P aeruginosa group were 47.6721.8, 59.3222.8, 81.8917.7, 49.5821.7
respectively. Though the values of FEV1, FVC, FEV1/FVC and PEFR in P aeruginosa group were decreased they
were not statistically significant.

Conclusion: P aeruginosa was the main colonizing bacteria especially in patients having air fluid levels on
radiology which can also be a predictor of bacterial colonization. Lung functions were de-creased in patients
having P Aeruginosa in their sputum as compared to non P Aeruginosa group but they were statistically not
significant.

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