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  • Calcipotriol Monohydrate

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    Jai Murugesh
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    Calcipotriol monohydrate BP is a white or almost white crystalline powder with the chemical name (5Z,7E,22E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1a,3b,24-triol monohydrate and molecular weight of 430.6. It is practically insoluble in water but freely soluble in ethanol and slightly soluble in methylene chloride, and it is sensitive to light with its activity due to both calcipotriol and its reversible isomer pre-calcipotriol in solution.

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    calipotriol

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    Calcipotriol monohydrate BP is a white or almost white crystalline powder with the chemical name (5Z,7E,22E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1a,3b,24-triol monohydrate and molecular weight of 430.6. It is practically insoluble in water but freely soluble in ethanol and slightly soluble in methylene chloride, and it is sensitive to light with its activity due to both calcipotriol and its reversible isomer pre-calcipotriol in solution.

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    © All Rights Reserved
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    18 views1 page

    Calcipotriol Monohydrate

    Uploaded by

    Jai Murugesh
    Calcipotriol monohydrate BP is a white or almost white crystalline powder with the chemical name (5Z,7E,22E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1a,3b,24-triol monohydrate and molecular weight of 430.6. It is practically insoluble in water but freely soluble in ethanol and slightly soluble in methylene chloride, and it is sensitive to light with its activity due to both calcipotriol and its reversible isomer pre-calcipotriol in solution.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
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    Calcipotriol Monohydrate BP

    Chemical Name : (5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-


    5,7,10(19),22-tetraene-1a,3b,24-triol monohydrate.

    Empirical Formula : C27H40O3,H2O

    Molecular Weight : 430.6

    Chemical Structure :

    Description : White or almost white, crystalline powder.

    Solubility : Practically insoluble in water, freely soluble in


    ethanol (96 per cent), slightly soluble in methylene
    chloride.
    It is sensitive to light.
    A reversible isomerisation to pre-calcipotriol takes
    place in solution, depending on temperature and
    time. The activity is due to both compounds.

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