The Task of Remedial English V

Journal of Diabetes Mellitus

By :

Isnaini Siti Fajria 10214016

STATUS Of NURSING Undergraduate

THE FACULTY OF HEALTH SCIENCES
INSTITUTE OF HEALTH SCIENCES BHAKTI WIYATA
KEDIRI
2017
 MAPPING JOURNAL
NO Title The Name of The Publication Methods Result
Journal Researcher
1 Saxagliptin Benjamin M. Scirica, Was Randomly assigned 16,492 A primary end-point event occurred in
and M.D., M.P.H., published patients with type 2 diabetes 613 patients in the saxagliptin group and
Cardiovasc Deepak L. Bhatt, M.D., on who had a history of, or in 609 patients in the placebo group
ular M.P.H., September were at risk for, (7.3% and 7.2%, respectively, according
Outcomes Eugene Braunwald, M.D., 2, cardiovascular events to to 2-year KaplanMeier estimates; hazard
in Patients P. Gabriel Steg, M.D., 2013, and receive saxagliptin or ratio with saxagliptin, 1.00; 95%
with Type 2 Jaime Davidson, M.D., updated on placebo and followed them confidence interval [CI], 0.89 to 1.12;
Diabetes Boaz Hirshberg, M.D., September for a median of 2.1 years. P=0.99 for superiority; P<0.001 for
Mellitus 19, 2013 noninferiority); the results were similar in
Peter Ohman, M.D.,
the on-treatment analysis (hazard ratio,
Robert Frederich, M.D.,
1.03; 95% CI, 0.91 to 1.17). The major
Ph.D.,
secondary end point of a composite of
Stephen D. Wiviott, M.D.,
cardiovascular death, myocardial
Elaine B. Hoffman, Ph.D.,
infarction, stroke, hospitalization for
Matthew A. Cavender,
unstable angina, coronary
M.D., M.P.H.,
revascularization, or heart failure
Jacob A. Udell, M.D.,
occurred in 1059 patients in the
M.P.H.,
saxagliptin group and in 1034 patients in
Nihar R. Desai, M.D.,
the placebo group (12.8% and 12.4%,
 M.P.H., respectively, according to 2-year Kaplan
Ofri Mosenzon, M.D., Meier estimates; hazard ratio, 1.02; 95%
Darren K. McGuire, M.D., CI, 0.94 to 1.11; P=0.66). More patients
Kausik K. Ray, M.D., in the saxagliptin group than in the

Lawrence A. Leiter, M.D., placebo group were hospitalized for heart

Itamar Raz, M.D., failure (3.5% vs. 2.8%; hazard ratio, 1.27;

for the SAVOR-TIMI 53 95% CI, 1.07 to 1.51; P=0.007). Rates of

Steering Committee and adjudicated cases of acute and chronic

Investigators* pancreatitis were similar in the two

groups (acute pancreatitis, 0.3% in the
saxagliptin group and 0.2% in the
placebo group; chronic pancreatitis,
<0.1% and 0.1% in the two groups,
respectively).
2 Low John E Madias Date Study design and study Data on the prevalence of HTN and DM
prevalence received: 20 patients on the 33,894 patients (first analysis)
of diabetes May 2014; All 1932 papers on TTS with TTS are shown in Table 1. Patients
mellitus in accepted: published between 2001 and who suffered TTS were mostly female, in
patients 11 January 2014, as of 22 February their mid 60s, with a prevalence of 57.4%
with 2015 2014, were accessed in for HTN and 16.8% for DM. Data on the
Takotsubo PubMed, employing the prevalence of HTN and DM in the 1085
syndrome: MeSH search term patients reported as individual cases
A plausible takotsubo,4 and 959 (794 (second analysis) with TTS are shown in
protective single, or more patients, Table 2. Patients who suffered TTS were
effect with case reports, and 165 patient mostly female, in their early 60s, with a
pathophysi case series, each comprising prevalence of 42.8% for HTN and 10.2%
ologic five to 24,701 patients) were for DM. One of the 113 patients with DM
connotation reviewed in their entirety in this subgroup was reported as having
(full text); when patient borderline hyperglycemia, but was
series included tabulations included herein as having DM. Data on
with age and other variables the prevalence of HTN and DM on the
of all reported patients, 32,809 patients with TTS from patient
patient series were included case series with data reported collectively
as multiple case reports of (third analysis) are shown on Table 3.
single patients, embedded in Patients who suffered TTS were mostly
the series. The remaining female, in their mid 60s, with a
973 papers were written in prevalence of 57.9% for HTN and 17.0%
languages other than for DM. Data on the prevalence of HTN
English (although the and DM on the 687 patients 60 years
Abstract in such papers was old with TTS reported individually
often available in English), (fourth analysis) are shown in Table 4.
could not be accessed Patients who suffered TTS were mostly
electronically in their female, in their early 70s, with a
entirety in the Icahn School prevalence of 50.4% for HTN and 11.9%
of Medicine at Mount Sinai
Levy Library, were review
articles, editorials, lettersto
th-editor referring to
published papers, or free
standing, but not including
patient case presentations,
or failed to provide
information on the prior
medical history of the
reported patients.
for DM. Finally data on the prevalence of
HTN and DM on the 550 patients 65
years old with TTS reported individually
(fifth analysis) are shown on Table 5.
Patients who suffered TTS were mostly
female, in their mid 70s, with a
prevalence of 52.2% for HTN and 12.5%
for DM.