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Abrams RC, Rosendahl E, Card C and Alexopoulos

GS (1994): Personality disorder correlates of late and
 early onset depression. Journal of the American
Geriatrics Society; 42: 727-731.
Abou Suleh MT, Collins J, George A, Anderson DN
and Ryan E , 1996 ,Platelet 5HT Transport in
Depression and the Effects of Treatment, current
psychiatry, Vol. 3 No.2 Dec.1996
Afana, A., Dalgard, O.S., Bjertness,E., Grunfeld, B.,
and Neda, T.( 2000 )The screening of Mental
disorders in primary health care setting in the Gaza
Strip.Egyptian Journal of Psychiatry, 23: 241 251.

American Academy of Child and Adolescent Psychiatry

(2007) : Practice parameter for the assessment and
treatment of children and adolescents with depressive
disorders. J Am Acad Child Adolesc Psychiatry 2007;
46:15031526
Angold,A.,Erkanli,A.,Farmer,E.M.Z.,Fairbank,J.A.,
Burns,B.J., Keeler,G., and Costello,E.J. ( 2002 ):
Psychiatric disorder, impairment and service use in rural
 a African American and white youth. Archives of
General Psychiatry.59: 893-901.
Arafa M, Ryad M, Sabry N, EL-Rakhawy M, Abdo, H
,2009 ,Dynamic Approaches in Anxiety and Depressive
Disorders: Defensive Styles and Parental Bonding,
Current Psychiatry , Vol. 16 No. 3 July 2009
Banazak DA (2000): Minor depression in primary care.
J Am Osteophath Assoc; 100: 783-787
Barbara L. Parry(2008), Perimenopausal Depression ,
Am J Psychiatry 165:1, January 2008 Chisholm D(2001
) :.The economic consequences of depression.
In:Dawson A,Tylee A, eds. Depression: social and
economic timebomb.London: BMJ Books, 2001:1219.

Birmaher,B., Ryan,N.D.,Brent,D.A., Dahl,R.E.,

Perel,J., and Nelson,B.N.(1996) Childhood and
adolescent depression : a review of the past 10 Years .
Part 1 . Journal of the American Academy of Child and
Adolescent psychiatry , 35 : 1427 1439 .
Bridge JA, Goldstein TR, Brent DA( 2006):
Adolescent suicide and suicidal behavior. J Child
Psychol Psychiatry 2006; 47:372394
 Fombonne E.( 1999 )True trends in affective disorders.
In: Cohen P,Slomkoski C, Robins LN, eds. Historical
and Geographical Influences on Psychopathology. New
Jersey: Laurence Erlbaum, 1999:11539
Halgin, R &Whitbourne, S ( 1993) , Abnormal
psychology , New York , Harcourt Brace Collage
Publisher
Heba Essawi', Hussein El- Orabi, Hala Mahfouz ,
Hadia Al- Sayed, , Azza Abou Ghalia, Taher Farid,
and Ali Khalifa , 1999 CORRELATION OF CORTISOL,
SEROTONIN AND LEPTIN WITH THE SYMPTOMATIC
PROFILE OF MAJOR DEPRESSION. Sci. Med. J.
ESCME, Vol. 11, No 2, April., 1999.
Jennifer Keller,. Lin Shen, B.A.Rowena G.
Gomez,.Amy Garrett, Ph.D.H. Brent Solvason,. and
Allan Reiss, Alan F. Schatzberg,(2008) : Hippocampal
and Amygdalar Volumes in Psychotic and Nonpsychotic
Unipolar Depression, (Am J Psychiatry 2008; 165:872
880)

Kaplan and sadok (2001) Comprehensive text

book of Psychiatry,Seventh edition.
Kendal , P Hammen , C (1995) , Abnormal psychology , New
Jersey , Houghton Mifflin company .
National Committee for Quality Assurance(2006):
The State of Healthcare Quality. Washington, DC.
Ormel J,Tiemens B.(1997) Depression in primary care.
 In Honig A,van Praag HM, eds. Depression: Neurobiological,
Psychopathological and Therapeutic
Otte C, McCaffrey J, Ali S, Whooley MA (2007 ):
Association of serotonin transporter polymorphism (5-
HTTLPR) with depression, perceived stress, and
norepinephrine in patients with coronary disease: the Heart
and Soul Study. Am J Psych 2007; 164:13791384
Sloan DM, Kornstein SG(2003): Gender differences in
depression and response to antidepressant treatment. Psychiatr
Clin North Am 2003; 26:581594