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2017 Fas1 Errata March PDF
2017 Fas1 Errata March PDF
OfficialUpdates,Corrections,andClarifications
March31,2017
Despiteourbestefforts,errorsdooccurduringtherevisionprocess.Thislistprimarilyaddressescontenterrors
thatmaycreateconfusion.Redsignifiesspecifictexttobedeletedandgreenisspecifictexttobeadded.We
checkeverysubmissionagainstyourreference(s),authoritativereferences,andexpertfacultytomaximizeclarity
andaccuracy.Pleasenotethatourgoalistoprovideahighyieldframeworkforoptimalexampreparationand
notacomprehensivetextbook.Ifyouwerethefirstindividualtosubmitareferencedcorrectionorclarificationto
usatwww.firstaidteam.comthatappearsintheerrataorinthenextedition,youwillreceiveagiftcertificatein
thanks.Goodluckwithyourstudies!
TheFirstAid/USMLERxTeam
CATEGORIESOFUPDATES
MajorCorrections Factualerrorsthatcouldinterferewithcomprehension
MinorCorrections Lesssignificanterrorsthatmaycauseconfusion
Clarifications Thetextisaccurate,butcouldbewrittenmoreclearlyorminorformattingissues
(misalignments,indents,etc)thatmayconfuse
MAJORCORRECTIONS
33 Nucleotides Incolumn2,replacethelines:
"Deaminationofadeninemakesguanine."
Withthefollowing:
Deaminationofadeninemakeshypoxanthine.
Deaminationofguaninemakesxanthine.
Deaminationof5methylcytosinemakesthymine.
69 Enzymeterminology Thedefinitionsforsynthase/synthetaseareinaccurate.
Thetextshouldread,"Combines2moleculesinto1(condensationreaction)
eitherusingenergyfromATPorotherhighenergyphosphates(synthetase,eg,
PRPPsynthetase)orenergyfromothersources(synthase,eg,citrate
synthase,glycogensynthase)."
MINORCORRECTIONS
60 Geneticdisordersby Inthechromosome11row,thecloseparenthesisinthecolumn3textshould
chromosome movetoread,Wilmstumor,globingenedefects(eg,sicklecelldisease,
thalassemia),MEN1.
86 Ketonebodies Inthelastsentenceofcolumn2,replaceBothprocessescauseabuildupof
acetylCoA,whichshuntsglucoseandFFAtowardtheproductionofketone
bodieswith"BothprocessescauseabuildupofacetylCoA,whichshunts
aminoacidsandFFAtowardtheproductionofketonebodies."
51 Cloningmethods Replace"CloningistheproductionofarecombinantDNAmoleculethatisself
perpetuating"with"CloningistheproductionofarecombinantDNAmolecule
inabacterialhost."
55 Modesofinheritance Undermitochondrialinheritance,column3,replaceMELASsyndrome
(mitochondrialencephalopathy,lacticacidosis,andstrokelikeepisodes)with
MELASsyndrome(mitochondrialmyopathy,encephalopathy,lacticacidosis,
strokelikeepisodes).