DATA QSAR

Senyawa X EC50 MR
1 H 11.8 0 1.03
2 Cl 1.24 0.71 6.03
3 NO2 4.58 -0.28 7.36
4 Cn 26.5 -0.57 6.33
5 C6H5 0.24 1.96 25.36
6 N(CH3)2 4.39 0.18 15.55
7 I 0.35 1.12 13.94

Hubungan Antara Log 1/EC50 terhadap

Log 1/EC50 Log 1/EC50

0 -1.0718820212
1
0.71 -0.0934216867
f(x) = 0.8169669336x - 0.7664422422
-0.28 -0.6608654807 R 0.5
= 0.887884543
-0.57 -1.4232458631
0
1.96 0.6197887586

Axis Title
-1 -0.5 0 0.5 1 1.5 2
0.18 -0.6424645256 -0.5
1.12 0.4559319561
-1

-1.5

-2
Axis Title

Hubungan Antara Log 1/EC50 terhadap MR

MR Log 1/EC50
1.03 -1.0718820212
6.03 -0.0934216867 Log 1/EC50
7.36 -0.6608654807 1
6.33 -1.4232458631
0.5
25.36 0.6197887586 f(x) = 0.0683437598x - 1.1404210144
R = 0.527618568
15.55 -0.6424645256 0
Axis Title

13.94 0.4559319561 0 5 10 15 20 25
-0.5

-1

-1.5

-2
Axis Title
 -1.5

-2
Axis Title

Hubungan Antara Log 1/EC50 Terhadap MR dan phi

MR Log 1/EC50
0 1.03 -1.0718820212
0.71 6.03 -0.0934216867
-0.28 7.36 -0.6608654807
-0.57 6.33 -1.4232458631
1.96 25.36 0.6197887586
0.18 15.55 -0.6424645256
1.12 13.94 0.4559319561 Persamaan Log 1/EC50 =

y = 0,818316

Regresi Log 1/EC50 Eksperimen dengan Log 1/EC50 Prediksi

Log 1/EC50 Eksperimen Log 1/EC50 Prediksi R2

-1.0718820212 -0.7651855352 0.942277 Log 1/EC50 E
-0.0934216867 -0.1851296865
-0.6608654807 -0.995515974
-1.4232458631 -1.2326323601
0.6197887586 0.8340969188
-0.6424645256 -0.6206449574
0.4559319561 0.1488786368 -2 -1.5
 1/EC50 Log 1/EC50
0.08474576 -1.0718820212
0.80645161 -0.0934216867
0.21834061 -0.6608654807
0.03773585 -1.4232458631
4.16666667 0.6197887586
0.22779043 -0.6424645256
2.85714286 0.4559319561

50 terhadap

Log 1/EC50

0.8169669336x - 0.7664422422
.887884543

0 0.5 1 1.5 2 2.5 Col umn C

Li nea r (Col umn C)

Axis Title

0 terhadap MR

Log 1/EC50

0.0683437598x - 1.1404210144
.527618568

10 15 20 25 30 Col umn C
Li nea r (Col umn C)

Axis Title
 Axis Title

hadap MR dan phi

Regresi Linier
-0.0001898404 0.81831697 -0.76499
0.0247697203 0.2282487999 0.232139
0.8878861894 0.3128431611 #N/A
15.839015459 4 #N/A

Persamaan Log 1/EC50 = 0,81831697 x - 0,00018984 MR - 0,76499

y = 0,81831697 x - 0,00018984 x - 0,76499

an Log 1/EC50 Prediksi

Log 1/EC50 Eksperimen dengan Log 1/EC50 Prediksi

1

0.5

0
-2 -1.5 -1 -0.5 0 0.5 1

-0.5

-1

-1.5