ADME TARTRAZINA

ID Valor
BBB 0.0395981
Buffer_solubility_mg_L 80524.1
Caco2 0.381506
CYP_2C19_inhibition Non
CYP_2C9_inhibition Non Toxicidad Tartrazina

CYP_2D6_inhibition Non ID Value

CYP_2D6_substrate Non algae_at 0.0684437
CYP_3A4_inhibition Non Ames_test mutagen
CYP_3A4_substrate Non Carcino_Mouse positive
HIA 42.185912 Carcino_Rat positive
MDCK 0.194757 daphnia_at 0.0921286
Pgp_inhibition Inhibitor hERG_inhibition low_risk
Plasma_Protein_Binding 97.014142 medaka_at 0.0239746
Pure_water_solubility_mg_L 9.56634 minnow_at 0.0288996
Skin_Permeability -2.1943* TA100_10RLI negative
SKlogD_value -2.65041 TA100_NA negative
SKlogP_value -2.65041 TA1535_10RLI positive
SKlogS_buffer -0.76189 TA1535_NA negative
SKlogS_pure -4.68707
Indigotina
 ADME INDIGOTINA
ID Value
BBB 0.0375433
Buffer_solubility_mg_L 525.012
Caco2 0.411507
CYP_2C19_inhibition Non
CYP_2C9_inhibition Inhibitor
CYP_2D6_inhibition Non
CYP_2D6_substrate Non TOXICIDAD INDIGOTINA

CYP_3A4_inhibition Non ID Value

CYP_3A4_substrate Substrate algae_at 0.201926

HIA 84.352801 Ames_test mutagen

MDCK 0.440494 Carcino_Mouse negative

Pgp_inhibition Non Carcino_Rat negative

Plasma_Protein_Binding 82.632073 daphnia_at 0.628774

Pure_water_solubility_mg_L 24.454 hERG_inhibition ambiguous

Skin_Permeability -2.54492 medaka_at 1.02747

SKlogD_value -2.77724 minnow_at 0.277201

SKlogP_value -2.77724 TA100_10RLI negative

SKlogS_buffer -2.90346 TA100_NA negative

SKlogS_pure -4.23528 TA1535_10RLI negative

TA1535_NA positive