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  • Keto Genesis

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    orzowey10
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    This document outlines the metabolic pathway of ketogenesis, which produces ketone bodies from acetyl-CoA. The pathway involves thiolase combining two acetyl-CoA molecules to form acetoacetyl-CoA. HMG-CoA synthase then uses acetyl-CoA to produce HMG-CoA, which is broken down by HMG-CoA lyase into acetoacetate. Acetoacetate can then spontaneously decarboxylate to produce acetone or be reduced to D-β-hydroxybutyrate by dehydrogenase.

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    Fórmula ketogénesis

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    This document outlines the metabolic pathway of ketogenesis, which produces ketone bodies from acetyl-CoA. The pathway involves thiolase combining two acetyl-CoA molecules to form acetoacetyl-CoA. HMG-CoA synthase then uses acetyl-CoA to produce HMG-CoA, which is broken down by HMG-CoA lyase into acetoacetate. Acetoacetate can then spontaneously decarboxylate to produce acetone or be reduced to D-β-hydroxybutyrate by dehydrogenase.

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    © All Rights Reserved
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    0 views1 page

    Keto Genesis

    Uploaded by

    orzowey10
    This document outlines the metabolic pathway of ketogenesis, which produces ketone bodies from acetyl-CoA. The pathway involves thiolase combining two acetyl-CoA molecules to form acetoacetyl-CoA. HMG-CoA synthase then uses acetyl-CoA to produce HMG-CoA, which is broken down by HMG-CoA lyase into acetoacetate. Acetoacetate can then spontaneously decarboxylate to produce acetone or be reduced to D-β-hydroxybutyrate by dehydrogenase.

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    © All Rights Reserved
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    of 1

    + 2 Acetyl-CoA

    Thiolase
    CoA-SH

    Acetoacetyl-CoA

    Acetyl-CoA
    HMG-CoA synthase
    CoA-SH

    β-hydroxy-β-methylglutaryl-CoA
    (HMG-CoA)

    HMG-CoA lyase
    Acetyl-CoA

    Acetoacetate

    D-β-hydroxybutyrate
    +
    Non-enzymatic dehydrogenase
    decarboxylation

    Acetone D-β-hydroxybutyrate

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