Title (en)

Confocal raman spectroscopy for dermatological studies

Title (de)
Konfokale Ramanspektroskopie für dermatologische Studien

Title (fr)
Spectroscopie confocal Raman pour études dermatologiques

Publication
EP 1760440 A1 20070307 (EN)

Application
EP 05018928 A 20050831

Priority
EP 05018928 A 20050831

Abstract (en)
Use of Confocal Raman Spectroscopy (CRS) for dermatological studies, including a method for determining the thickness of the Stratum Comeum
(SC) on a test area of the skin, and to a method for quantifying the effectiveness of a skin care composition. The methods of the invention can be
carried in vitro (either artificial skin or a sample of skin) or in vivo (directly on the human skin of a person).

Inventor
  • CROWTHER JONATHAN MARK (GB)
  • BLENKIRON PETER (GB)
  • MATTS PAUL JONATHAN (GB)
  • SIEG ANKE (GB)

Applicant
PROCTER & GAMBLE (US)

IPC 8 full level (invention and additional information)

G01J 3/44  (2006.01); G01N 33/50  (2006.01); G06Q 30/02  (2012.01)

CPC (invention and additional information)

G01J 3/44 (2013.01); G01N 21/65 (2013.01); G06Q 30/0242 (2013.01); G06Q 30/0269 (2013.01); G01N 2021/656 (2013.01)

Citation (applicant)
• C.N. BANWELL: "FUNDAMENTALS OF MOLECULAR SPECTROSCOPY", 1983, MCGRAW HILL
• P.J. CASPERS ET AL.: "Automated depth-scanning Confocal Raman microspectrometer for rapid in vivo determination of
water concentration of water concentration profile in human skin", J. RAMAN SPECTROSC., vol. 31, 2000, pages 813 - 818,
XP008010393, DOI: doi:10.1002/1097-4555(200008/09)31:8/9<813::AID-JRS573>3.0.CO;2-7
• P.J. CASPERS ET AL.: "In vivo Confocal Raman Microspectroscopy of the Skin: Noninvasive Determination of Molecular
Concentration Profiles", THE JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 133, no. 3, March 2001 (2001-03-01), pages
434 - 442, XP002220321, DOI: doi:10.1046/j.1523-1747.2001.01258.x
• HORIBA JOBIN YVON: "RAMAN UPDATE", 2005, WINTER, article "Confocal Raman Microscopy for Cosmetic Applications"
• PETER CASPERS PH.D. THESIS: "IN-VIVO SKIN CHARACTERIZATION BY CONFOCAL RAMAN SPECTROSCOPY", 2003,
ERASMUS UNIVERSITY

Citation (search report)

• [XA] CASPERS P J ET AL: "Combined in vivo confocal Raman spectroscopy and confocal microscopy of human skin.",
BIOPHYSICAL JOURNAL, vol. 85, no. 1, July 2003 (2003-07-01), pages 572 - 580, XP002366550, ISSN: 0006-3495
• [DX] CASPERS P J ET AL: "In Vivo Confocal Raman Microspectroscopy of the Skin: Noninvasive Determination of Molecular
Concentration Profiles", JOURNAL OF INVESTIGATIVE DERMATOLOGY, NEW YORK, NY, US, vol. 116, no. 3, March 2001
(2001-03-01), pages 434 - 442, XP002220321, ISSN: 0022-202X
• [A] NORLEN LARS ET AL: "Stratum corneum swelling. Biophysical and computer assisted quantitative assessments", ARCHIVES
OF DERMATOLOGICAL RESEARCH, vol. 289, no. 9, 1997, pages 506 - 513, XP002366551, ISSN: 0340-3696

Cited by
ITPD20110110A1; US9714936B2; EP2799865A4; RU2605300C2

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR MK YU

EPO simple patent family

EP 1760440 A1 20070307; CN 101253396 A 20080827; US 2007049831 A1 20070301; US 2007050202 A1 20070301; US 2011082352 A1
20110407; US 7862507 B2 20110104; US 8114022 B2 20120214; WO 2007026325 A1 20070308

INPADOC legal status

2011-12-14 [18R] REFUSED
- Effective date : 20101111

2007-11-14 [AKX] PAYMENT OF DESIGNATION FEES

- Designated State(s) : AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK
TR

2007-05-16 [17Q] FIRST EXAMINATION REPORT

- Effective date : 20070413
2007-04-25 [17P] REQUEST FOR EXAMINATION FILED
- Effective date : 20070314

2007-03-07 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document : A1
- Designated State(s) : AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK
TR

2007-03-07 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Countries : AL BA HR MK YU