Sample Test Paper, SPSC Exams.

Note: For Exam Preparation Purpose, designed after consultation with SPSC
Passed Candidates

1. In which of the following is the absorption of water greatest?

A. colon
B. jejunum
C. duodenum
D. stomach

2. Blood brain barrier is made up of:

A. astrocytes
B. oligodendrocytes
C. oligodendroglia
D. microglia

3. Iron is stored in the body in all of the following except:

A. spleen
B. R.E. system
C. gall bladder
D. bone marrow

4. The skeletal muscle is controlled by:

A. parasympathetic nerves
B. spinal nerves
C. sympathetic nerves
D. olfactory nerve

5. Ureter is a tube that connects:

A. the bladder with the urethra

B. the kidneys with the bladder
C. the two kidneys with each other
D. the urethra with bladder

6. Which of the following routes of administration is (are) least likely to be

influenced by the first-pass effect?

A. Inhalation
B. Trasdermal
C. Intramuscular
D. Intravenous
E. All of the above

7. The biological half life of a drug:

A. Is a constant physical property of the drug

B. Is a constant chemical property of the drug
 C. Is the time for one-half of the therapeutic activity to be lost
D. May be decreased by giving the drug by rapid IV injection
E. Depends entirely on the route of administration

8. Pharmacokinetics is:

A. The study of biological and therapeutic effects of drugs

B. The study of absorption, distribution, metabolism and excretion of
drugs
C. The study of mechanisms of drug action
D. The study of methods of new drug development

9. A low therapeutic or even sub-therapeutic concentration may be adequate for

some patients because they require only a low plasma concentration, due to:

A. differences in disease severity

B. tissue sensitivity
C. pathophysiology
D. All of the above

10.Gingivitis refers to inflammation of the:

A. pharynx
B. tongue
C. gums
D. larynx
E. salivary gland
11.Spoon shape nails are the indication of:

A. Deficiency of iron
B. Deficiency of vitamins
C. Deficiency of proteins
D. Deficiency of lipids

12.Urinary tract infaction is common in:

A. Males
B. Females
C. Children
D. Neonates

13.Meningitis that begins as an infection of the lungs is caused by:

A. Flavobacterium meningosepticum
B. Streptococcus pneumonia
C. Cryptococcus neoformans
D. Haemophilus influenza
E. Neisseria meningitidis

14.The chromosome number of unicellular organisms that reproduce sexually is

maintained by the process of:

A. mitosis and cytoplasmic division

B. mitosis and fertilization
 C. meiosis and mitosis
D. meiosis and fertilization
E. meiosis and cytoplasmic division

15.Neonatal viral diseases result from:

A. rubella virus
B. eb virus
C. measles virus
D. none of the above

16.Sifter top containers are used for:

A. powder
B. semisolid
C. liquids
D. glass

17.Slugging is also called _________.

A. Compaction
B. Compression
C. Double Compression
D. None of the above

18.A prescription label should contain all of the following information except:

A. The quantity dispensed

B. Directions for use
C. The patient’s diagnosis
D. The physician’s name

19.Regulatory authorities never require clinical trials for:

A. new drugs
B. new surgical procedures
C. new medical devices
D. new herbal medicinal products

20.At an inspection, which of the following items are reviewed?

A. documents, facilities, hospital records

B. SOP, facilities, patients
C. publications, documents, correspondence
D. CVs, publications, correspondence

21.________ is integral to an effective pharmaceutical quality system.

I. Quality risk management

II. Facilitating continual improvement
III. Establishing and maintaining a state of control
A. I only
B. II only
C. III only
D. I & II only
E. I, II & III