PROTEIN TRAFFICKING allison_nicholas | July 16, 2018

Cytosolic
cytosolic protein remains
protein in the cytosol

(No Signal Sequence)

Cytosol: mRNA
travels here and
Cytosol
translation
begins here for
Nucleus:
all proteins.
transcription
occurs here.

Membrane-Bound Proteins
Secreted Proteins Lysosomal Proteins Membrane-Bound
Lysosomal Proteins Secreted Proteins Proeins

Signal
Rough ER Signal Sequence
Translation Sequence is appears
finishes here. within the first anywhere in the
Signal few amino acids sequence and
sequences translated and can appear
trigger is removed several times.
movement from upon Signal
cytosol completion of Sequence isn?t
translation removed, and
remains as part
of the
transmembrane
portion.