USP Endotoxin Limits for Common Injectables

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Product name Endotoxin Limit Endotoxin Limit 2 Endotoxin Limit 3

(where applicable) (where applicable)

A
Acetazolamide for Injection 0.5 EU/mg
Acetic Acid Irrigation 0.5 EU/ml
Acyclovir for Injection 0.174 EU/mg
Adenosine Injection 11.62 EU/mg for rapid 5.95 EU/mg for
intravenous injection continuous peripheral
intravenous infusion
Alcohol in Dextrose Injection 0.5 EU/ml
Alfentanil Injection 10 EU/ml
Alprostadil Injection 5 EU/100ug
Alteplase 1 EU/mg
Alteplase for Injection 1 EU/mg
Amifostine for Injection 0.2 EU/mg
Amikacin Sulfate Injection 0.33 EU/mg
Aminocaproic Acid Injection 0.05 EU/mg
Aminohippurate Sodium 0.04 EU/mg
Injection
Aminopentamide Sulfate 25 EU/mg
Injection
Aminophylline Injection 1 EU/mg
13
Ammonia N Injection 175/V EU/ml (V = max.
total dose in ml at the
expiration time)
Ammonium Chloride 1.72 EU/ mEq of chloride
Injection
Amobarbital Sodium 0.4 EU/mg
Amobarbital Sodium for 0.4 EU/mg
Injection
Amoxicillin 0.25 EU/mg
Amoxicillin for Injectable 0.25 EU/mg
Suspension
Amphotericin B for Injection 5 EU/mg for parenterals 0.9 EU/mg for
intrathecals
Ampicillin 0.15 EU/mg
Ampicillin and Sulbactam for 0.17 EU /
Injection (1mg of mix of amp & sulb -
0.67 and 0.33 mg,
respectively)
Ampicillin for Injectable 0.15 EU/mg
Suspension
Ampicillin for Injection 0.15 EU/mg
Ampicillin Sodium 0.15 EU/mg if labeled sterile
or processed into injectable
Anileridine Injection 7.2 EU/mg
Anticoagulant Citrate 5.56 EU/ml
Dextrose Solution
Anticoagulant Citrate 5.56 EU/ml
Phosphate Dextrose Adenine
Solution
Anticoagulant Citrate 5.56 EU/ml
Phosphate Dextrose Solution
Anticoagulant Heparin 2.5 EU/ml
Solution
Anticoagulant Sodium Citrate 5.56 EU/ml
Solution
Arginine Hydrochloride 0.01 EU/mg
Injection
Ascorbic Acid Injection 1.2 EU/mg
Atenolol Injection 33.3 EU/mg
Atracurium Besylate Injection 5.56 EU/mg
Atropine Sulfate Injection 55.6 EU/mg
Azathioprine Sodium for 1 EU/mg of azathioprine
Injection
Aztreonam 0.17 EU/mg if labeled sterile
or processed into injectable
Aztreonam for Injection 0.17 EU/mg

B
Bacitracin 0.01 EU / Bacitracin Unit if
labeled sterile or processed
into injectable
Bacitracin for Injection 0.01 EU / Bacitracin Unit
Bacteriostatic Sodium 1 EU/ml
Chloride Injection
Bacteriostatic Water for 0.5 EU/ml
Injection
Benztropine Mesylate 55.6 EU/mg
Injection
Benzylpenicilloyl Polylysine 5833 EU/ml
Injection
Betamethasone Sodium 29.2 EU/mg Betamethasone
Phosphate and
Betamethasone Acetate
Injectable Suspension
Betamethasone Sodium 29.2 EU/mg Betamethasone
Phosphate Injection
Bethanechol Chloride 25 EU/mg
Injection
Biperiden Lactate Injection 83.3 EU/mg
Bleomycin for Injection 10EU/Bleomycin Unit
Bleomycin Sulfate 10EU/Bleomycin Unit
Bretylium Tosylate in 0.2 EU/mg Bretylium
Dextrose Injection Tosylate
Bretylium Tosylate Injection 0.2 EU/mg
Brompheniramine Maleate 35.7 EU/mg
Injection
Bumetanide Injection 350 EU/mg
Bupivacaine Hydrochloride 1.6 Eu/mg Bupivacaine
and Epinephrine Injection Hydrochloride
Bupivacaine Hydrochloride in 1.8 EU/mg Bupivacaine
Dextrose Injection Hydrochloride
Bupivacaine Hydrochloride 2.5 EU/mg
Injection
Butorphanol Tartrate 88 EU/ mg
Injection

C
Caffeine and Sodium 0.7 EU/mg
Benzoate Injection
Calcium Chloride Injection 0.2 EU/mg
Calcium Gluceptate Injection 0.32 EU/mg
Calcium Gluconate Injection 0.17 EU/mg
Calcium Levulinate Injection 35.7 EU/mg
Capreomycin for Injection .35 EU/mg
Capreomycin Sulfate .35 EU/mg
Carbenicillin Disodium 0.05 EU/mg Carbenicillin
Carbenicillin for Injection 0.05 EU/mg
Carboplatin for Injection 0.54 EU/mg
Carboprost Tromethamine 714.3 EU/mg
Injection
Cefamandole Nafate 0.15 EU/mg Cefamandole
Cefamandole Nafate for 0.15 EU/mg Cefamandole
Injection
Cefazolin for Injection 0.15 EU/mg
Cefazolin Injection 0.15 EU/mg
Cefazolin Sodium 0.15 EU/mg
Cefepime for Injection 0.06 EU/mg
Cefepime Hydrochloride 0.04 EU/mg if labeled sterile
or processed into injectable
Cefmetazole for Injection 0.2 EU/mg
Cefmetazole Injection 0.2 EU/mg
Cefmetazole Sodium 0.2 EU/mg
Cefonicid for Injection 0.35 EU/mg
Cefonicid Sodium 0.35 EU/mg
Cefoperazone for Injection 0.2 EU/mg
Cefoperazone Injection 0.2 EU/mg
Cefoperazone Sodium 0.2 EU/mg
Ceforanide 0.25 EU/mg if labeled sterile
or processed into injectable
Ceforanide for Injection 0.25 EU/mg
Cefotaxime for Injection 0.2 EU/mg
Cefotaxime Injection 0.2 EU/mg
Cefotetan 0.17 EU/mg if labeled sterile
or processed into injectable
Cefotetan Disodium 0.17 EU/mg if labeled sterile
or processed into injectable
Cefotetan for Injection 0.17 EU/mg
Cefotetan Injection 0.17 EU/mg
Cefoxitin for Injection 0.13 EU/mg
Cefoxitin Injection 0.13 EU/mg
Cefoxitin Sodium 0.13 EU/mg if labeled sterile
or processed into injectable
Ceftazidime 0.1 EU/mg if labeled sterile
or processed into injectable
Ceftazidime for Injection 0.1 EU/mg
Ceftizoxime for Injection 0.1 EU/mg
Ceftizoxime Injection 0.1 EU/mg
Ceftizoxime Sodium 0.1 EU/mg if labeled sterile
or processed into injectable
Ceftriaxone for Injection 0.2 EU/mg
Ceftriaxone Injection 0.2 EU/mg
Ceftriaxone Sodium 0.2 EU/mg if labeled sterile
or processed into injectable
Cefuroxime for Injection 0.1 EU/mg
Cefuroxime Injection 0.1 EU/mg
Cefuroxime Sodium 0.1 EU/mg if labeled sterile
or processed into injectable
Cephalothin for Injection 0.13 EU/mg
Cephalothin Injection 0.13 EU/mg
Cephalothin Sodium 0.13 EU/mg if labeled sterile
or processed into injectable
Cephapirin for Injection 0.17 EU/mg
Cephapirin Sodium 0.17 EU/mg if labeled sterile
or processed into injectable
Cephradine 0.2 EU/mg if labeled sterile
or processed into injectable
Cephradine for Injection 0.2 EU/mg
Chloramphenicol 0.2 EU/mg if used in
injectable dosage form
Chloramphenicol Injection 0.2 EU/mg
Chloramphenicol Sodium 0.2 EU/mg of
Succinate chloramphenicol if labeled
sterile or processed into
injectable
Chloramphenicol Sodium 0.2 EU/mg of
Succinate for Injection chloramphenicol
Chlordiazepoxide 3.57 EU/mg
Hydrochloride for Injection
Chloroquine Hydrochloride 0.7 EU/mg
Injection
Chlorothiazide Sodium for 0.3 EU/mg
Injection
Chlorpheniramine Maleate 8.8 EU/mg
Injection
Chlorpromazine 6.9 EU/mg
Hydrochloride Injection
Chorionic Gonadotropin 0.03 EU / USP
Chorionic Gonadotropin Unit
Chorionic Gonadotropin for 0.03 EU / USP Chorionic
Injection Gonadotropin Unit
Chromic Chloride Injection 16.7 EU/ug of chromium
32
Chromic Phosphate P 175/V EU/ml (V = max. tota
Suspension l dose in ml at the expiratio
n time)
Chromium Cr 51 Edetate 175/V EU/ml (V = max. tota
Injection l dose in ml at the expiratio
n time)
Cilastatin Sodium 0.17 EU/mg of cilastatin if
labeled sterile
Cimetidine in Sodium 0.5 EU/mg of cimetidine
Chloride Injection hydrochloride
Cimetidine Injection 0.5 EU/mg
Cisplatin for Injection 2 EU/mg
Citric Acid, Magnesium 2.8 EU/ml
Oxide, and Sodium
Carbonate Irrigation
Clavulanate Potassium 0.03 EU/mg if labeled sterile
or processed into injectable
Clindamycin for Injection 0.58 EU/mg
Clindamycin Injection 0.58 EU/mg
Clindamycin Phosphate 0.58 EU/mg if labeled sterile
or processed into injectable
Codeine Phosphate Injection 5.8 EU/mg
Colchicine Injection 166.7 EU/mg
Colistimethate for Injection 2 EU/mg
Colistimethate Sodium 2 EU/mg if labeled sterile or
processed into injectable
Corticotropin for Injection 3.1 EU / USP Corticotropin
Unit
Corticotropin Injection
Corticotropin Zinc Hydroxide
Injectable Suspension
Cupric Chloride Injection
Cupric Sulfate Injection
Cyanocobalamin Injection
Cyclophosphamide for
Injection
Cyclosporine Injection
Cysteine Hydrochloride
Injection
Cytarabine
Cytarabine for Injection
3.1 EU / USP Corticotropin
Unit
3.1 EU / USP Corticotropin
Unit
250 EU/mg of copper
250 EU/mg of copper
0.4 EU/ug
0.2 EU/mg
0.84 EU/mg (use 1:10
dilution; mix .1ml with .1ml
LAL reagent on vortex mixer
for 5 sec.)
0.7 EU/mg
0.07 EU/mg if labeled sterile
or processed into injectable
0.07 EU/mg

D
Dacarbazine for Injection 0.52 EU/mg
Dactinomycin 100 EU/mg
Dactinomycin for Injection 100 EU/mg
Daunorubicin Hydrochloride 4.3 EU/mg of daunorubicin
for Injection
Deferoxamine Mesylate 0.33 EU/mg if labeled sterile
or processed into injectable
Deferoxamine Mesylate for 0.33 EU/mg
Injection
Desoxycorticosterone Acetate 71.4 EU/mg
Injection
Desoxycorticosterone 2.78 EU/mg
Pivalate Injectable
Suspension
Dexamethasone Acetate 21.7 EU/mg
Injectable Suspension
Dexamethasone Injection 21 EU/mg
Dexamethasone Sodium 31.3 EU/mg
Phosphate Injection
Dextran 1 25 EU/g
Dextran 40 1 EU/ml
Dextran 40 in Dextrose 1 EU/ml
Injection
Dextran 40 in Sodium 1 EU/ml
Chloride Injection
Dextran 70 0.5 EU/ml
Dextran 70 in Dextrose 0.5 EU/ml
Injection
Dextran 70 in Sodium
Chloride Injection
Dextrose and Sodium
Chloride Injection
Dextrose Injection
Diatrizoate Meglumine and
Diatrizoate Sodium Injection
Diatrizoate Meglumine
Injection
Diatrizoate Sodium Injection
Diazepam Injection
Diazoxide Injection
Dibucaine Hydrochloride
Injection
Dicyclomine Hydrochloride In
jection
Diethylstilbestrol
Diphosphate Injection
Diethylstilbestrol Injection
Digitoxin Injection
Digoxin Injection
Dihydroergotamine Mesylate
Injection
Dihydrostreptomycin
Injection
Dihydrostreptomycin Sulfate
Dimethicone
0.5 EU/ml
10 EU/g
0.5 EU/ml for 10 EU/ml for
Injections containing less th Injections containing
an 5% of dextrose between 5% and 70
% of dextrose
1.8 EU/ml for 3.6 EU
Injections containing less th for Injections contain
an 60% of dia. meg. ing 60% or more of
dia. meglumine
1.1 EU/ml for 5 EU/ml
Injections containing less th for Injections contain
an 50% dia. meg. ing 50% or more dia.
meg.
5.6 EU/ml for Injections 1.3 EU/ml for 5 EU/ml for
containing 20% of Injections containing Injections containing
diatrizoate sodium 25% of diatrizoate 50% of diatrizoate
sodium sodium
11.6 EU/mg
0.5 EU/mg
35.7 EU/mg
17.2 EU/mg
0.7 EU/mg
0.7 EU/mg
111 EU/mg
200 EU/mg
175 EU/mg
0.5 EU/mg
no limit listed but USP
Endotoxin RS referenced
10 EU/ml where intended
for use in coating containers
that come in contact with
articles for parenteral use.
(Mix 1ml of Dimethicone
with 4ml of
polydimethylsiloxane having
a viscosity of 0.65
centistokes, by mixing on a
vortex mixer for 1min. in an
extraction tube. Add 10ml
water, and mix on a vortex
mixer for not less than 60
minutes. Allow layers to
 separate, and use lower
aqueous layer as test
specimen.
Dimethyl Sulfoxide Irrigation 0.5 EU/ml
Diphenhydramine Hydrochlor 3.4 EU/mg
ide Injection
Dipyridamole Injection 8.8 EU/mg
Dobutamine for Injection 5.56 EU/mg
Dobutamine in Dextrose 5.56 EU/mg of dobutamine
Injection
Dobutamine Injection 2.08 EU/mg
Dolasetron Mesylate 2.7 EU/mg
Injection
Dopamine Hydrochloride and 16.67 EU/mg of dopamine
Dextrose Injection hydrochloride
Dopamine Hydrochloride 16.67 EU/mg
Injection
Doxapram Hydrochloride 3.3 EU/mg
Injection
Doxorubicin 2.2 EU/mg (from prepared
Hydrochloride Injection 1.1mg/ml doxorubicin
hydrochloride)
Doxorubicin Hydrochloride 2.2 EU/mg (from prepared
for Injection 1.1mg/ml doxorubicin
hydrochloride)
Doxycycline for Injection 1.14 EU/mg
Doxycycline Hyclate See Doxycycline for
Injection
Droperidol Injection 35.7 EU/mg
Dyphylline Injection 0.7 EU/mg

E
Edetate Calcium Disodium 0.01 EU/mg
Injection
Edetate Disodium Injection 0.2 EU/mg

Edrophonium Chloride Injecti 8.33 EU/mg

on
Emetine Hydrochloride 5.4 EU/mg
Injection
Ephedrine Sulfate Injection 1.7 EU/mg
Epinephrine Injection 357 EU/mg
Ergonovine Maleate Injection 700 EU/mg
Ergotamine Tartrate Injection 357 EU/mg
Erythromycin Lactobionate 1 EU/mg of erythromycin
for Injection
Estradiol Injectable 250 EU/mg
Suspension
Estrone Injectable 88 EU/mg
Suspension
Ethacrynate Sodium for 5 EU/mg
Injection
Etoposide Injection 2 EU/mg (for a conc. of 0.31
mg etoposide activity per
ml)
Extended Insulin Human Zinc 80 EU / 100 USP Insulin
Suspension Units
Extended Insulin Zinc 80 EU / 100 USP Insulin
Suspension Units

F
Fenoldopam Mesylate 84 EU/mg
Injection
Fentanyl Citrate Injection 50 EU/mg
Ferumoxides Injection 12.5 EU/ml
Fludarabine Phosphate for 7.7 EU/mg
Injection
Fludeoxyglucose 18F Injection 175/V EU/ml (V = max.
total dose in ml at the expir
ation time)
11
Flumazenil C Injection 175/V EU/ml (V = max.
total dose in ml at the expir
ation time)
Flunixin Meglumine Injection 4.54 EU/mg of flunixin
Fluorodopa F 18 Injection 175/V EU/ml (V = max.
total dose in ml at the expir
ation time)
Fluorouracil Injection 0.33 EU/mg
Fluphenazine Hydrochloride 166.7 EU/mg
Injection
Folic Acid Injection 357.1 EU/mg
Fructose and Sodium 0.5 EU/ml
Chloride Injection
Fructose Injection 0.5 EU/ml
Furosemide Injection 3.6 EU/mg

G
Gadodiamide 3.5 EU/g
Gadodiamide Injection 0.029 EU/mg
Gadopentetate Dimeglumine 25 EU/ml
Injection
Gadoteridol Injection 8.3 EU/ml
Gallamine Triethiodide 5 EU/mg
Injection
Gallium Citrate 67Ga Injection 175/V EU/ml (V = max.
total dose in ml at the
expiration time)
Ganciclovir for Injection 0.84 EU/mg
Gentamicin Sulfate If processed into injectable,
see gentamicin injection
Gentamicin Injection 0.71 EU/mg
Glucagon for Injection 125 EU/mg
Glycine Irrigation 0.5 EU/ml
Glycopyrrolate Injection 555.5 EU/mg
Gonadorelin for Injection 3.6 EU/ug
Guaifenesin for Injection 0.05 EU/mg

H
Half-Strength Lactated 0.5 EU/ml
Ringer's and Dextrose
Injection
Haloperidol Injection 71.4 EU/mg
Heparin Calcium 0.03 EU / USP Heparin Unit
Heparin Calcium Injection 0.03 EU / USP Heparin Unit
Heparin Lock Flush Solution 0.5 EU/ml
Heparin Sodium 0.03 EU / USP Heparin Unit
Heparin Sodium Injection 0.03 EU / USP Heparin Unit
Histamine Phosphate 125 EU/mg
Injection
Hyaluronidase for Injection 2.30 EU / USP
Hyaluronidase Unit
Hyaluronidase Injection 2.30 EU / USP
Hyaluronidase Unit
Hydralazine Hydrochloride 1.45 EU/mg
Injection
Hydrocortisone Injectable 1.25 EU/mg
Suspension
Hydrocortisone Sodium 1.25 EU/mg of
Phosphate Injection hydrocortisone
Hydrocortisone Sodium 1.25 EU/mg of
Succinate for Injection hydrocortisone
Hydromorphone 88 EU/mg
Hydrochloride Injection
Hydroxocobalamin Injection 0.4 EU/ug
Hydroxyzine Hydrochloride 3.6 EU/mg
Injection
Hyoscyamine Sulfate 714.3 EU/mg
Injection

I
Idarubicin Hydrochloride for 8.9 EU/mg of
Injection idarubicin hydrochloride
solution at 0.07 mg/ml
Ifosfamide 0.125 EU/mg
if labeled sterile or
processed into injectable
Ifosfamide for Injection
Imipenem
Imipenem and Cilastatin for
Injectable Suspension
Imipenem and Cilastatin for
Injection
Imipramine Hydrochloride
Injection
Inamrinone Injection
Indigotindisulfonate Sodium
Injection
Indium 111In Capromab
Pendetide Injection
Indium 111In Chloride
Solution
Indium 111In Pentetate
Injection
Indium 111In Satumomab
Pendetide Injection
Indium 111In Pentetreotide
Injection
Indocyanine Green
Indocyanine Green for
Injection
Indomethacin for Injection
Insulin
Insulin Human
Insulin Human Injection
Insulin Human Zinc
Suspension
Insulin Injection
Insulin Lispro
Insulin Lispro Injection
Insulin Zinc Suspension
Inulin in Sodium Chloride
Injection
Invert Sugar Injection
0.125 EU/mg
0.17 EU/mg if labeled sterile
0.23 EU/mg of imipenem
and 0.23 EU/mg of cilastatin
0.17 EU/mg of imipenem
and 0.17 EU/mg of cilastatin
5 EU/mg
0.5 EU/mg
5 EU/mg
175/V EU/ml (V = max.
total dose in ml at the
expiration time)
175/V EU/ml (V = max.
total dose in ml at the
expiration time)
14/V EU/ml (V = max.
total dose in ml at the
expiration time)
175/V EU/ml (V = max.
total dose in ml at the
expiration time)
175/V EU/ml (V = max.
total dose in ml at the
expiration time)
7.1 EU/mg if labeled sterile
or processed into injectable
7.1 EU/mg
20 EU/mg of indomethacin
at 1.0 mg/ml
10 EU/mg
10 EU/mg
80 EU / 100 USP Insulin
Units
80 EU / 100 USP Insulin
Units
80 EU / 100 USP Insulin
Units
10 EU/mg, using Kinetic
Chromogenic method
80 EU / 100 USP Insulin
Units, using Kinetic
Chromogenic
80 EU / 100 USP Insulin
Units
0.1 EU/mg of inulin
0.5 EU/ml
 123
Iobenguane I Injection 175/V EU/ml (V = max.
total dose in ml at the
expiration time)
131
Iobenguane I Injection 175/V EU/ml (V = max.
total dose in ml at the
expiration time)
125
Iodinated I Albumin 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
Iodinated 131I Albumin See
Aggregated Injection Technetium 99Tcm Albumin
Aggregated Injection
131
Iodinated I Albumin 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
Iodipamide Meglumine 3.6 EU/ml
Injection
Iodixanol Injection 0.2 EU / 50 mg of iodine
123
Iodohippurate Sodium I 175/V EU/ml (V = max. tota
Injection l dose in ml at the expiratio
n time)
131
Iodohippurate Sodium I 175/V EU/ml (V = max. tota
Injection l dose in ml at the expiratio
n time)
Iohexol Injection 0.2 EU / 50 mg of iodine
Iopamidol Injection 0.6 EU/mg of iodine
Iophendylate Injection 0.9 EU/mg
Iopromide Injection 1.25 EU/ml
Iothalamate Meglumine and 3.35 EU/ml
Iothalamate Sodium
Injection
Iothalamate Meglumine 0.9 EU/ml
Injection
Iothalamate Sodium 3.35 EU/ml
Injection
125
Iothalamate Sodium I 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
Ioversol Injection 1.4 EU/ml
Ioxaglate Meglumine and no limit listed but USP
Ioxaglate Sodium Injection Endotoxin RS referenced
Ioxilan 0.2 EU / 50 mg of iodine
Ioxilan Injection 0.2 EU / 50 mg of iodine
Iron Dextran Injection 0.5 EU / mg of iron
Iron Sorbitex Injection 10.0 EU/ ml
Iron Sucrose Injection 3.7 EU/mg of iron
Isoflupredone Acetate 125 U/ mg of isoflupredone
acetate.
Isoflupredone Acetate
Injectable Suspension
Isoniazid Injection
Isophane Insulin Human
Suspension
Isophane Insulin Suspension
Isoproterenol Hydrochloride
Injection
Isoxsuprine Hydrochloride
Injection
125 U/ mg of isoflupredone
acetate.
0.3 EU/ mg of Isoniazid
80 EU / 100 USP Insulin
Units
80 EU / 100 USP Insulin
Units
1250.0 EU/ mg of
isoproterenol hydrochloride
37.7 EU/mg

K
Kanamycin Injection 0.67 EU/mg
Kanamycin Sulfate 0.67 EU/mg
Ketamine Hydrochloride 0.4 EU/mg
Injection
Ketorolac Tromethamine 5.8 EU/mg
Injection

L
Labetalol Hydrochloride 1.2 EU/mg
Injection
Lactated Ringer's and 0.5 EU/ml
Dextrose Injection
Lactated Ringer's Injection 0.5 EU/ml
Leucovorin Calcium Injection 1.95 EU/mg
Levocarnitine Injection 0.1 EU/mg
Levorphanol Tartrate 125.0 EU/mg
Injection
Lidocaine Hydrochloride 1.1 EU/mg
Lidocaine Hydrochloride and 1.1 EU/mg of Lidocaine
Dextrose Injection Hydrochloride
Lidocaine Hydrochloride and 0.7 EU/mg of Lidocaine
Epinephrine Injection Hydrochloride
Lidocaine Hydrochloride 1.1 EU/mg
Injection
Lincomycin Hydrochloride 0.5 EU/mg of Lincomycin
Lincomycin Injection 0.5 EU/mg of Lincomycin
Lorazepam Injection 100.0 EU/ mg

M
Magnesium Sulfate in 0.039 EU/mg of Magnesium
Dextrose Injection Sulfate
Magnesium Sulfate Injection 0.09 EU/mg
Mangafodipir Trisodium 0.13 EU/mg
Manganese Chloride Injection 0.45 EU/ug of Manganese
Manganese Sulfate Injection 0.45 EU/ug of Manganese
Mannitol in Sodium Chloride 0.04 EU/mg of Manitol
Injection
Mannitol Injection 0.04 EU/ mg for injections 2.5 EU/ g for
containing %10 or less injections containing
Manitol greater than %10
Manitol
Mechlorethamine 12.5 EU/mg
Hydrochloride for Injection
Menadiol Sodium 25.0 EU/mg
Diphosphate Injection
Menadione Injection 58.3 EU/mg
Menotropins 2.5 EU/ USP Follicle
Stimulating Hormone Unit
Menotropins for Injection 2.5 EU/ USP Follicle
Stimulating Hormone Unit
Meperidine Hydrochloride 2.4 EU/mg
Injection
Mepivacaine Hydrochloride 0.8 EU/mg of Mepivacaine
and Levonordefrin Injection Hydrochloride
Mepivacaine Hydrochloride 0.8 EU/mg
Injection
Meropenem 0.125 EU/mg
Meropenem for Injection 0.125 EU/mg
Mesoridazine Besylate 7.0 EU/mg
Injection
Mespiperone 11C Injection 175/V EU/ml (V = max.
total dose in ml at the
expiration time)
Metaraminol Bitartrate 3.5 EU/mg Metaraminol
Injection
Methadone Hydrochloride 8.8 EU/mg
Injection
Methionine 11C Injection 175/V EU/ml (V = max.
total dose in ml at the
expiration time)
Methocarbamol Injection 0.2 EU/mg
Methohexital Sodium for 0.5 EU/mg
Injection
Methotrexate for Injection 0.4 EU/mg of Methotrexate
Sodium
Methotrexate Injection 0.4 EU/mg of Methotrexate
Sodium
Methotrimeprazine Injection 17.9 EU/mg
Methyldopate Hydrochloride 0.5 EU/mg
Injection
Methylene Blue Injection 2.5 EU/ml
Methylergonovine Maleate 1.7 EU/ug
Injection
Methylprednisolone Sodium 0.17 EU/mg of
Succinate for Injection Methylprednisolone
Metoclopramide Injection 2.5 EU/mg
Metoprolol Tartrate Injection 25.0 EU/mg
Metronidazole Injection 0.35 EU/mg
Mezlocillin for Injection 0.06 EU/mg of Mezlocillin
Mezlocillin Sodium 0.06 EU/mg of Mezlocillin
Miconazole Injection 0.1 EU/mg
Minocycline for Injection 1.25 EU/mg
Minocycline Hydrochloride 1.25 EU/mg of Minocycline
Mitomycin for Injection 10 EU/mg
Mitoxantrone Injection 5 EU/mg
Modified Lactated Ringer's 0.5 EU/ml
and Dextrose Injection
Morphine Sulfate Injection 17 EU/mg for parenterals 14.29 EU/mg for
intrathecals
Morrhuate Sodium Injection 1.4 EU/mg
Multiple Electrolytes and 0.5 EU/ml
Dextrose Injection Type 2
Multiple Electrolytes and 0.5 EU/ml
Dextrose Injection Type 3
Multiple Electrolytes and 0.5 EU/ml
Dextrose Injection Type 4
Multiple Electrolytes and Dex 0.5 EU/ml
trose Injection Type 1
Multiple Electrolytes Injection 0.5 EU/ml
Type 1
Multiple Electrolytes Injection 0.5 EU/ml
Type 2

N
Nafcillin for Injection 0.13 EU/mg
Nafcillin Injection 0.13 EU/mg
Nafcillin Sodium 0.13 EU/mg if labeled sterile
or processed into injectable
Nalorphine Hydrochloride 11.6 EU/mg
Injection
Naloxone Hydrochloride 500 EU/mg
Injection
Neomycin for Injection 1.3 EU/mg
Neomycin Sulfate 1.3 EU/mg if labeled sterile
or processed into injectable
Netilmicin Sulfate Injection 1.25 EU/mg of netilmicin
Niacin Injection 3.5 EU/mg
Niacinamide Injection 3.5 EU/mg
Nitroglycerin Injection 0.1 EU/ug
Norepinephrine Bitartrate 83.4 EU/mg of
Injection norepinephrine

O
Ondansetron Injection
Orphenadrine Citrate
Injection
Oxacillin for Injection
Oxacillin Sodium
Oxymorphone Hydrochloride
Injection
Oxytetracycline
Oxytetracycline for Injection
Oxytetracycline
Hydrochloride
Oxytetracycline Injection
Oxytocin Injection
9.9 EU/mg
5.8 EU/mg
0.2 EU/mg
0.2 EU/mg if labeled sterile
or processed into injectable
238.1 EU/mg
0.4 EU/mg if labeled sterile
or processed into injectable
0.4 EU/mg
0.4 EU/mg if labeled sterile
or processed into injectable
0.4 EU/mg
35.7 EU / USP Oxytocin Unit

P
Paclitaxel
Paclitaxel Injection
Papaverine Hydrochloride
Injection
Penicillin G Benzathine
Penicillin G Benzathine &
Penicillin G Procaine
Injectable Suspension
Penicillin G Benzathine
Injectable Suspension
Penicillin G Potassium for
Injection
Penicillin G Potassium
Injection
Penicillin G Procaine and
Dihydrostreptomycin Sulfate
Injectable Suspension
Penicillin G Procaine for
Injectable Suspension
Penicillin G Procaine
Injectable Suspension
Penicillin G Procaine,
Dihydrostreptomycin Sulfate,
and Prednisolone Injectable
Suspension
0.4 EU/mg
0.67 EU/mg
2.9 EU/mg
0.01 EU / 100 Penicillin G
Units if labeled sterile or
processed into injectable
see Penicillin G Procaine
Injectable
0.01 EU / 100 Penicillin G
Units
0.01 EU / 100 Penicillin G
Units
0.01 EU / 100 Penicillin G
Units
0.01 EU / 100 Penicillin G
Units
0.01 EU / 100 Penicillin G
Units
0.01 EU / 100 Penicillin G
Units
0.01 EU / 100 Penicillin G
Units
Penicillin G Procaine, 0.01 EU / 100 Penicillin G
Dihydrostreptomycin Sulfate, Units
Chlorpheniramine Maleate,
and Dexamethasone
Injectable Suspension
Penicillin G Sodium 0.01 EU / 100 Penicillin G
Units
Penicillin G Sodium for 0.01 EU / 100 Penicillin G
Injection Units
Penicillin G Procaine 0.01 EU / 100 Penicillin G
Units if labeled sterile or
processed into injectable
Pentazocine Injection 5.8 EU/mg
Pentazocine Lactate Injection 5.8 EU/mg
Pentobarbital Sodium 0.8 EU/mg
Injection
Perflutren Protein-Type A 0.5 EU/ml
Microspheres for Injection
Perflutren Protein-Type A 0.5 EU/ml
Microspheres Injectable
Suspension
Perphenazine Injection 35.7 EU/mg
Phenobarbital Sodium 0.8 EU/mg if labeled sterile
or processed into injectable
Phenobarbital Sodium for 0.8 EU/mg
Injection
Phenobarbital Sodium 0.3 EU/mg
Injection
Phentolamine Mesylate for 5.8 EU/mg
Injection
Phenylbutazone Injection 1.1 EU/mg
Phenylephrine Hydrochloride 25 EU/mg
Injection
Phenytoin Sodium Injection 0.3 EU/mg
Physostigmine Salicylate 83.4 EU/mg
Injection
Phytonadione Injectable 14 EU/mg
Emulsion
Phytonadione Injection 14 EU/mg
Piperacillin 0.07 EU/mg if labeled sterile
or processed into injectable
Piperacillin for Injection 0.07 EU/mg
Piperacillin Sodium 0.07 EU/mg if labeled sterile
or processed into injectable
Plicamycin for Injection 100 EU/mg
Potassium Acetate Injection 8.80 EU/mEq
Potassium Chloride for 8.80 EU/mEq
Injection Concentrate
Potassium Chloride in 0.5 EU/ml
Dextrose and Sodium
Chloride Injection
Potassium Chloride in 0.5 EU/ml
Dextrose Injection
Potassium Chloride in 0.5 EU/ml
Lactated Ringer's and
Dextrose Injection
Potassium Chloride in 0.5 EU/ml
Sodium Chloride Injection
Potassium Phosphates 1.10 EU/mg
Injection
Pralidoxime Chloride 0.1 EU/mg if labeled sterile
or processed into injectable
Pralidoxime Chloride for 0.1 EU/mg
Injection
Prednisolone Sodium 5 EU/mg
Phosphate Injection
Prednisolone Sodium 5.8 EU/mg of prednisolone
Succinate for Injection
Prednisolone Tebutate 8.8 EU/mg
Injectable Suspension
Prednisone Injectable 2.27 EU/mg
Suspension
Prilocaine and Epinephrine 0.9 EU/mg of prilocaine
Injection hydrochloride
Prilocaine Hydrochloride 0.9 EU/mg
Injection
Procainamide Hydrochloride 0.35 EU/mg
Injection
Procaine and Tetracaine 0.6 EU/mg of procaine
Hydrochlorides and hydrochloride
Levonordefrin Injection
Procaine Hydrochloride 0.6 EU/mg if labeled sterile
or processed into injectable
Procaine Hydrochloride and 0.6 EU/mg of procaine
Epinephrine Injection hydrochloride
Procaine Hydrochloride 0.6 EU/mg
Injection
Prochlorperazine Edisylate 17.9 EU/mg of
Injection prochlorperazine
Promazine Hydrochloride 1.8 EU/mg
Injection
Promethazine Hydrochloride 5.0 EU/mg
Injection
Prompt Insulin Zinc 80 EU / 100 USP Insulin
Suspension Units
Propoxycaine and Procaine 0.8 EU/mg of propoxycaine
Hydrochlorides and hydrochloride
Levonordefrin Injection
Propoxycaine and Procaine 0.8 EU/mg of propoxycaine
Hydrochlorides and hydrochloride
Norepinephrine Bitartrate
Injection
Propranolol Hydrochloride 55.6 EU/mg
Injection
Protamine Sulfate for 7 EU/mg
Injection
Protamine Sulfate Injection 7 EU/mg
Protein Hydrolysate Injection 0.5 EU/mg
Pyridostigmine Bromide 17 EU/mg
Injection
Pyridoxine Hydrochloride 0.4 EU/mg
Injection

Q
Quinidine Gluconate Injection 0.6 EU/mg

R
11
Raclopride C Injection 175/V EU/ml (V = max. tota
l dose in ml at the expiratio
n time)
Ranitidine in Sodium Chloride 7 EU/mg of ranitidine
Injection
Ranitidine Injection 7 EU/mg
Repository Corticotropin 3.1 EU / USP Corticotropin
Injection Unit
Reserpine Injection 71.5 EU/mg
Riboflavin Injection 7.1 EU/mg
Rifampin for Injection 0.5 EU/mg (from 10mg/ml
solution diluted down to
0.12mg/ml)
Ringer's and Dextrose 0.5 EU/ml
Injection
Ringer's Injection 0.5 EU/ml
Ringer's Irrigation 0.5 EU/ml
Ritodrine Hydrochloride 0.5 EU/mg
Injection
Rose Bengal Sodium 131I 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
82
Rubidium Chloride Rb 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
S
153
Samarium Sm Lexidronam 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
Sargramostim 5 EU/mg
Sargramostim for Injection 50 EU/mg
Scopolamine Hydrobromide 555 EU/mg
Injection
Secobarbital Sodium 0.9 EU/mg if labeled sterile
or processed into injectable
Secobarbital Sodium for 0.9 EU/mg
Injection
Secobarbital Sodium 0.9 EU/mg
Injection
Selenious Acid Injection 3.5 EU/ug
Sincalide for Injection 83.3 EU/ug
Sisomicin Sulfate Injection 0.5 EU/mg
11
Sodium Acetate C Injection 175/V EU/ml (V = max.
total dose in ml at the
expiration time)
Sodium Acetate Injection 3.9 EU/mEq
Sodium Bicarbonate Injection 5 EU/mEq
Sodium Chloride Injection 0.5 EU/ml (labeled amount 3.6 EU/ml (labeled a
of sodium chloride is 0.5% - mount of sodium
0.9%) chloride is 3.0% -
24.3%)
Sodium Chloride Irrigation 0.5 EU/ml
51
Sodium Chromate Cr 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
18
Sodium Fluoride F Injection 175/V EU/ml (V = max.
total dose in ml at the
expiration time)
123
Sodium Iodide I Solution 175/V EU/ml (V = max.
total dose in ml at the
expiration time)
131
Sodium Iodide I Solution 175/V EU/ml (V = max.
total dose in ml at the
expiration time)
Sodium Lactate Injection 2 EU/mEq
Sodium Nitrite Injection 0.33 EU/mg
Sodium Nitroprusside 0.05 EU/ug if labeled sterile
or processed into injectable
Sodium Nitroprusside for 0.05 EU/ug
Injection
Sodium Pertechnetate 99Tcm 175/V EU/ml (V = max. tota
Injection l dose in ml at the expiratio
n time)
 32
Sodium Phosphate P 175/V EU/ml (V = max. tota
Solution
Sodium Phosphates Injection
Sodium Thiosulfate Injection
Spectinomycin for Injectable
Suspension
Spectinomycin Hydrochloride
Sterile Erythromycin
Gluceptate
Sterile Erythromycin
Lactobionate
Sterile Vancomycin
Hydrochloride
Sterile Water for Inhalation
Sterile Water for Injection
Sterile Water for Irrigation
Streptomycin for Injection
Streptomycin Injection
Streptomycin Sulfate
89
Strontium Chloride Sr
Injection
Succinylcholine Chloride
Succinylcholine Chloride for
Injection
Succinylcholine Chloride
Injection
Sufentanil Citrate Injection
Sulbactam Sodium
Sulfadiazine Sodium
Injection
T
Technetium 99Tcm (Pyro- and
trimeta-) Phosphates
Injection
Technetium 99Tcm Albumin
Aggregated Injection
Technetium 99Tcm Albumin
Colloid Injection
l dose in ml at the expiratio
n time)
1.1 EU/mg
0.03 EU/mg
??
0.09 EU/mg of
spectinomycin if labeled
sterile or processed into
injectable
1 EU/mg of erythromycin
1 EU/mg of erythromycin
0.33 EU/mg of Vancomycin
0.5 EU/ml
0.25 EU/ml
0.25 EU/ml
0.25 EU/mg
0.25 EU/mg
0.25 EU/mg if labeled sterile
or processed into injectable
175/V EU/ml (V = max.
total dose in ml at the
expiration time)
2 EU/mg if labeled sterile or
processed into injectable
2 EU/mg
2 EU/mg
6.25 EU/ml
0.17 EU/mg of sulbactam if
labeled sterile or processed
into injectable
0.1 EU/mg
175/V EU/ml (V = max.
total dose in ml at the
expiration time)
175/V EU/ml (V = max.
total dose in ml at the
expiration time)
175/V EU/ml (V = max.
total dose in ml at the
expiration time)
 99
Technetium Tcm Albumin
175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
Technetium 99Tcm Apcitide 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
Technetium 99Tcm 175/V EU/ml (V = max.
Arcitumomab Injection total dose in ml at the
expiration time)
99
Technetium Tcm Bicisate 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
99
Technetium Tcm 175/V EU/ml (V = max.
Depreotide Injection total dose in ml at the
expiration time)
Technetium 99Tcm Etidronate 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
Technetium 99Tcm 175/V EU/ml (V = max.
Exametazime Injection total dose in ml at the
expiration time)
99
Technetium Tcm Gluceptate 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
99
Technetium Tcm Lidofenin 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
Technetium 99Tcm 175/V EU/ml (V = max.
Mebrofenin Injection total dose in ml at the
expiration time)
Technetium 99Tcm Medronate 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
99
Technetium Tcm Mertiatide 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
99
Technetium Tcm 175/V EU/ml (V = max.
Nofetumomab Merpentan total dose in ml at the
Injection expiration time)
Technetium 99Tcm 175/V EU/ml (V = max.
Oxidronate Injection total dose in ml at the
expiration time)
Technetium 99Tcm Pentetate 175/V EU/ml (V = max.
Injection total dose in ml at the
expiration time)
99
Technetium Tcm 175/V EU/ml (V = max.
Pyrophosphate Injection total dose in ml at the
expiration time)
99
Technetium Tcm Red Blood 175/V EU/ml (V = max.
Cells Injection total dose in ml at the
expiration time)
Technetium 99Tcm
Sestamibi Injection
99
Technetium Tcm Succimer
Injection
Technetium 99Tcm Sulfur
Colloid Injection
Technetium 99Tcm
Tetrofosmin Injection
Terbutaline Sulfate Injection
Testosterone Injectable
Suspension
Tetracaine Hydrochloride
Tetracaine Hydrochloride for
Injection
Tetracaine Hydrochloride in
Dextrose Injection
Tetracaine Hydrochloride
Injection
Tetracycline Hydrochloride
Tetracycline Hydrochloride
for Injection
201
Thallous Chloride Tl
Injection
Theophylline in Dextrose
Injection
Thiamine Hydrochloride
Injection
Thiopental Sodium for
Injection
Thiotepa for Injection
Thiothixene Hydrochloride for 88 EU/mg of thiothixene
Injection
Thiothixene Hydrochloride
Injection
Ticarcillin and Clavulanic Acid 0.07 EU/mg of ticarcillin
for Injection
Ticarcillin and Clavulanic Acid 0.07 EU/mg of ticarcillin
Injection
Ticarcillin Disodium
Ticarcillin for Injection
175/V EU/ml (V = max.
total dose in ml at the
expiration time)
175/V EU/ml (V = max.
total dose in ml at the
expiration time)
175/V EU/ml (V = max.
total dose in ml at the
expiration time)
175/V EU/ml (V = max.
total dose in ml at the
expiration time)
1250 EU/mg
3.5 EU/mg
0.7 EU/mg if labeled sterile
or processed into injectable
0.7 EU/mg
1 EU/mg
0.7 EU/mg
0.5 EU/mg if labeled sterile
or processed into injectable
0.5 EU/mg
175/V EU/ml (V = max.
total dose in ml at the
expiration time)
1 EU/mg of anhydrous
theophylline
3.5 EU/mg
1 EU/mg
6.25 EU/mg
88 EU/mg of thiothixene
0.05 EU/mg if labeled sterile
or processed into injectable
0.05 EU/mg
Ticarcillin Monosodium 0.05 EU/mg if labeled sterile
or processed into injectable
Tiletamine and Zolazepam 0.07 EU/mg of combined
for Injection tiletamine and zolazepam
equivalents
Tiletamine Hydrochloride 0.07 EU/mg of tiletamine if
labeled sterile or processed
into injectable
Tilmicosin Injection 0.5 EU/mg
Tobramycin 2 EU/mg if labeled sterile or
processed into injectable
Tobramycin for Injection 2 EU/mg
Tobramycin Inhalation 60 EU/ml
Solution
Tobramycin Injection 2 EU/mg
Tobramycin Sulfate 2 EU/mg if labeled sterile or
processed into injectable
Tolazoline Hydrochloride 0.8 EU/mg
Injection
Tolbutamide 0.35 EU/mg of tolbutamide
sodium if labeled sterile or
processed into injectable
Tolbutamide for Injection 0.35 EU/mg of tolbutamide
sodium
Triamcinolone Acetonide 4.4 EU/mg
Injectable Suspension
Triamcinolone Diacetate 7.1 EU/mg
Injectable Suspension
Triamcinolone Hexacetonide 17.2 EU/mg
Injectable Suspension
Trifluoperazine Hydrochloride 172 EU/mg of
Injection trifluoperazine
Triflupromazine 5.8 EU/mg
Hydrochloride Injection
Trimethobenzamide 1.8 EU/mg
Hydrochloride Injection
Tripelennamine 4.6 EU/mg
Hydrochloride Injection
Tromethamine for Injection 0.03 EU/mg
Tubocurarine Chloride 10 EU/mg
Injection

U
Urea 0.003 EU/mg
Urea for Injection 0.003 EU/mg

V
Valrubicin Intravesical 0.14 EU/ mg of Valrubicin
Solution
Vancomycin Hydrochloride 0.33 EU/mg of Vancomycin
for Injection
Vancomycin Injection 0.33 EU/mg
Vasopressin Injection 17.0 EU/ Vasopressin Unit
Verapamil Hydrochloride 16.7 EU/mg
Injection
Verteporfin 0.5 EU/mg
Vidarabine 0.5 EU/mg except when
used in opthalmic dosage
forms
Vinblastine Sulfate 10.0 EU/mg
Vinblastine Sulfate for 10.0 EU/mg
Injection
Vincristine Sulfate for 100.0 EU/ mg
Injection
Vincristine Sulfate Injection 62.5 EU/mg
Warfarin Sodium for 24.0 EU/mg
Injection

W
Water for Injection 0.25 EU/ml
15
Water O Injection 175/V EU/ml (V = max.
total dose in ml at the
expiration time)

X
133
Xenon Xe Injection 175/V EU/ml (V = max.
total dose in ml at the
expiration time)
Xylazine Injection 1.7 EU/mg

Y
Yohimbine Injection 45.5 EU/mg

Z
Zidovudine Injection 1.0 EU/mg
Zinc Chloride Injection 25.0 EU/mg Zinc
Zinc Sulfate Injection 25.0 EU/mg Zinc
Zolazepam Hydrochloride 0.07 EU/mg Zolazepam