Modifiable Risk Factors Partially Modifiable Risk Factors Modifiable Risk Factors

*Age *Hypertension *Smoking

*Sex *Cardiac Impairments *Fat and Salt Intake
*Race *Blood Lipid Abnormalities *Obesity
*Heredity *Diabetes Mellitus *Sedentary Lifestyle

Atherothrombotic Disease Embolic Disease Small vessel disease HPN Amyloid angiopathy

lipid deposition dislodged thrombi microaretromata or elevated BP chronic deposition of beta

elevation amyloid sheets in
formation of plaque travel in the occlusion of endothelial of blood the tunica media of
bloodstream criface in the injury vessel blood vessel wall
narrowing of lumen penetrating
of blood vessel arteric degeneration of formation of rigid, fragile
tunica media Chacot-Bauchad and weak
turbulent blood flow smooth muscle aneurysm in blood vessel
lipohyalinotic
alteration in flow velocities smooth muscle vessels
is replaced with
intimal disruption collagenous fibers
or plaque rupture
unelastic
activation of clotting blood vessel
cascade
narrowing of lumen
activated platelets
adhere to plaque surface

fibrin clot
 Occlusion rupture increased ICP pain, dizziness

Hypoperfusion
Compression of the different lobes of
The brain
systemic HPON
Small arteries interruption of blood supply to the brain alteration in the functioning
Constrict in of the different lobes
reduces cerebral activation of attempt to ischemia
perfusion auto regulatory maintain distal tissue hypoperfusion FRONTAL LOBE: dysfunction in
pressure system pressure membrane the motor control of voluntary
movements (e.g. speech) and
hypoxia control of a variety of emotional
expressions

PARIETAL LOBE: dysfunction

in the general senses of the body
Tissue ischemia
TEMPORAL LOBE: dysfunction
in hearing and memory,
disequilibrium

OCCIPITAL LOBE: visual

abnormalities
Cell Death