UNIVERSITY OF SOUTHERN CALIFORNIA

R AY R . I R A N I H A L L
MOLECULAR BIOLOGY COLLOQUIUM SERIES

Nirupa Chaudhari, PhD from

The University of Miami,
Miller School of Medicine
Department of Physiology and Biophysics

will present on

" Single Neuron Transcriptomics to decipher

Structure, Function , Connectivity for Taste
pathways”

Abstract: Mammalian taste buds are innervated by

Friday, November 2, 2018
12:00 pm to 1:00 pm
Ray R. Irani Hall
1050 Childs Way, RRI 101
Los Angeles, CA 90089-2910
For additional information,
contact:
Emily Liman, PhD
liman@usc.edu
Jen Nelson
jmbrewer@usc.edu
neurons whose cell bodies reside in cranial sensory
ganglia. Our understanding of the functions of these
neurons have been hindered by a lack of knowledge
of their heterogeneity and markers to distinguish
them. Using single cell RNA sequencing of taste
ganglion neurons and unbiased transcriptome
analyses, we have corrected this shortfall. We have
identified clear molecular classes of gustatory
neurons, each with its own complement of
transcription factors and neurotransmitter response
profiles.We are now in the process of assessing the
functional characerisitics of these classes of neurons
and what their roles are in delivering sensory signals
to the brain.