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CLINICAL MANAGEMENT OF THE

OLDER ADULT

Effect of a Multimodal Educational Intervention on Use of


Urinary Catheters in Hospitalized Individuals
Richard E. Norman, MD, MASc,* Rebecca Ramsden, MN,† Leanne Ginty, MEd,† and
Samir K. Sinha, MD, DPhil*‡§

average of 14.5% and 15.0%, respectively, before the


BACKGROUND/OBJECTIVES: Urinary catheters are fre- intervention. Similar degrees of improvement were
quently used in hospital inpatients despite their association observed for individuals of all ages, although older adults
with greater morbidity and mortality. Reducing their remained more likely to be catheterized. The effect per-
unnecessary use can improve patient care. The objective of sisted over nearly 3 years of observed follow-up.
the current study was to determine the effectiveness of a CONCLUSIONS: A relatively simple multimodal educa-
multimodal nursing and physician education intervention tional intervention targeting nurses and physicians resulted
to reduce the unnecessary use of urinary catheters in adult in a significant and sustained reduction in CDPP and the
inpatients. proportion of participants catheterized. J Am Geriatr Soc
DESIGN: Quasi-experimental interrupted time series study. 2017.
SETTING: General internal medicine and surgical services
of a large urban teaching hospital. Key words: urinary catheter; patient safety; quality
PARTICIPANTS: Admissions to the services under study improvement; hospitalization
during the study period (September 2009 to February
2013) (N = 21,550).
INTERVENTION: A multimodal educational intervention
incorporating educational posters, small-group teaching
sessions, and changes to the hospital’s electronic health
records and nursing clinical documentation systems were
introduced to nurses and physicians.
U rinary catheterization is a frequent procedure in inpa-
tient settings. It is estimated that 16% to 25% of hos-
pitalized individuals have an indwelling catheter placed at
MEASUREMENTS: Mean catheter days per patient some point during their stay1 and that as many as 86% of
(CDPP) and incidence of urinary catheterization, measured those undergoing major operations are catheterized.2
at monthly intervals throughout the study period. Although sometimes clinically indicated, studies have
RESULTS: A decrease in mean CDPP of 5.6 and 6.5 days shown that 21% to 52% of catheters are used unnecessar-
(P < .001) respectively was observed on the medical and ily.3–5 This is problematic because urinary catheters expose
surgical services following the intervention. The monthly people to significant morbidity, including greater risk of
incidence of catheterization decreased by 3.0 percentage urinary tract infection (UTI) and bacteremia,6 as well as a
points on medical units and 6.4 percentage points on sur- greater likelihood of functional decline.7 For older adults,
gical units immediately after the intervention, from an who are more likely to be catheterized than younger indi-
viduals,8 the associated risks related to urinary catheteriza-
tion are even more significant because they contribute to
From the *Department of Medicine, University of Toronto; †Department longer hospital stays, greater risk of being discharged to a
of Nursing, Sinai Health System; ‡Division of General Internal Medicine location other than home, and greater risk of death while
and Geriatrics, Department of Medicine, Sinai Health System and in the hospital and within 90 days of discharge.7 The
University Health Network; and §Institute of Health Policy, Management
and Evaluation, University of Toronto, Toronto, Ontario, Canada. strong association between functional decline and urinary
catheterization has been attributed to the fact that urinary
Presented at the Plenary Session of the 2016 Annual Scientific Meeting of
the American Geriatrics Society on May 19, 2016 in Long Beach, catheters serve as single-point restraints, tethering people
California. to their beds and preventing the early mobilization that is
Address correspondence to Dr. Samir Sinha, Sinai Health System, Suite particularly needed for older adults to help prevent and
475, 600 University Avenue, Toronto, ON M5G 1X5, Canada. E-mail: reverse functional loss.1,9–11
samir.sinha@sinaihealthsystem.ca Several authors have identified a lack of familiarity
DOI: 10.1111/jgs.15074 with the specific indications for urinary catheterization

JAGS 2017
© 2017, Copyright the Authors
Journal compilation © 2017, The American Geriatrics Society 0002-8614/17/$15.00
2 NORMAN ET AL. 2017 JAGS

as a significant contributor to inappropriate catheteriza-


Measures and Statistical Analysis
tion.1,12–14 Examples of inappropriate indications
include urinary incontinence, cognitive impairment, lim- Data were collected using the hospital’s EMR. Catheter
itations in activities of daily living, inconvenience of use data were used to calculate two primary outcome
care, and multiple comorbidities.2,3,7,14,15 All of these parameters: mean catheter days per patient (CDPP) for
problems are more common in older adults. Other pre- individuals who were catheterized, and the incidence of
viously identified barriers to evidence-based use of uri- individuals who underwent indwelling urinary catheteriza-
nary catheters include communication problems tion in a given month (% catheterized). These data were
between doctors and nurses regarding the use of cathe- extracted from the hospital’s EMR, which tracks the pres-
ters, lack of clear criteria for when their removal is ence or absence of a urinary catheter on a per-nursing shift
warranted, incontinence, and lack of familiarity of basis; nurses completed data entry as part of routine chart-
nurses with perineal care principles.12,13 Addressing the ing.
knowledge gaps identified in these studies therefore is The data collected over the study period were struc-
a logical opportunity to inform the safer, more-appro- tured as a time series with monthly intervals, with mean
priate use of urinary catheters. CDPP and incidence of catheterization calculated for each
We thus introduced a multimodal educational inter- interval. The effect of the educational intervention on the
vention targeting nurses and physicians aimed at reducing primary outcome measures was assessed using a segmented
the unnecessary use of urinary catheters. This study pre- regression analysis of the time series. This analytical method
sents the outcomes of this intervention in a large cohort of is described extensively elsewhere.17,18 Briefly, it is a linear
individuals over a 3-year period. regression technique that includes a coefficient to reflect the
immediate effect of an intervention, a coefficient to identify
and adjust for any preintervention baseline trend, and a
METHODS
coefficient to identify and adjust for any postintervention
change in trend. The observed intervention effect is a con-
Study Setting and Population
stant, the baseline trend is a linear slope, and the change in
Mount Sinai Hospital is a 472-bed acute care teaching trend is a change in the slope. Terms that are statistically sig-
hospital in Toronto, Canada, that is part of the Sinai nificant within the model are relevant predictors of the out-
Health System. The study population included individu- come. For example, if an intervention term is statistically
als admitted to the medical and surgical services significant, then the intervention is deemed to have had a
between September 2009 and February 2013. We pur- significant effect on the outcome despite adjustment for pre-
posefully excluded people admitted to the dentistry, or postintervention trends. In the case of nonsignificant
ophthalmology, otolaryngology, and vascular surgery terms in the full model, the most-parsimonious model
services because of the minimal use of urinary catheters including only statistically significant terms was selected
in these specialties. We further excluded individuals using stepwise regression.17 This most-parsimonious model
admitted to the urology service because the specific use is provided as the final result.
of catheters remains fundamental to their interventions. The timing of the introduction of the educational
Approval was obtained from the local institutional intervention was February 2010. A 2-month transition per-
review board. iod (March and April 2010), similar to the one that others
have used,17,19 was assumed to allow the various interven-
tions to take effect. This period was not included in the
Multimodal Educational Intervention
analysis. The absence of autocorrelation was confirmed
The educational interventions consisted of passive mea- using the Durbin-Watson statistic and inspection of the
sures (educational posters reinforcing the appropriate residuals.
indications for catheters) and active measures (nurse-led To explore age-related patterns in catheter use, we
small-group sessions to discuss the appropriate use of compared the CDPP and incidence of urinary catheteriza-
urinary catheters). These measures emphasized evidence- tion according to age group (<65, 65–74, 75–84, ≥85) for
based indications for the use of urinary catheters and four distinct periods: the 6 months preceding the interven-
management techniques (e.g., insertion and maintenance) tion (September 2009–February 2010), the 6 months
in keeping with recommendations that the Centers for immediately after the transition period (May 2010–Octo-
Disease Control and Prevention provided at the time of ber 2010), the 6 months after the second phase of inter-
the intervention.16 The hospital’s electronic medical ventions (June 2011–November 2011), and the 6 months
record (EMR) was modified to display urinary catheter at the end of the follow up period (September 2012–Febru-
insertion and removal dates, allowing all healthcare pro- ary 2013). Histograms were constructed for the pre- and
viders to observe directly how much time any individual postintervention period to examine the duration of
had spent catheterized. A second phase of interventions catheterization. Regression was performed using SPSS
was introduced during the follow-up period, including Statistics version 20 (IBM, Armonk, NY). Reported
admission orders with prompts for appropriate indica- P-values are two-sided.
tions for catheterization and introduction of nursing rep-
resentatives to disseminate best practices. All nurses
RESULTS
working on the services during the study period were
exposed to the educational interventions. All physicians The data collected for the study are summarized in
were exposed to modifications to the EMR. Table 1. Of 21,550 unique admissions to the medical and
JAGS 2017 REDUCING URINARY CATHETER USE IN HOSPITALS 3

and 15.0% for surgical units. Immediately after the inter-


Table 1. Participant Characteristics
vention, there were absolute decreases in the monthly inci-
Total, Medicine, Surgery, dence of urinary catheterization of 3.0 percentage points
Characteristic N = 21,550 n = 6,444 n = 15,106 and 6.4 percentage points, respectively, that were sus-
tained during the 32-month postintervention period.
Catheterized, n (%) 2,540 (11.7) 609 (10.4) 1,931 (14.7) Before the intervention, CDPP was decreasing by 1.34
Age, mean  standard 57.0  20.3 64.4  20.2 53.5  19.5
catheter days per month on the medical service. After the
deviation
Male, n (%) 10,065 (46.7) 3,033 (47.1) 7,032 (46.6) intervention, this baseline trend leveled off (as demon-
Length of stay, days, strated by the observed positive trend change after the
Median 4 5 4 intervention of 1.31 catheter days per month, resulting in
Mean 7.6 9.4 6.9 a net slope of 0.03 catheter days per month). A similar
baseline trend and leveling off after the intervention was
seen for CDPP on the surgical units. There was a baseline
surgical services, 2,540 (11.7%) received a urinary catheter trend of decreasing incidence of catheterization on the
as part of their care. medicine units of 0.12% per month during the 32-month
Plots of the two outcome parameters for each service postintervention period. The surgical services had no pre-
are shown in Figure 1. The results of the segmented regres- existing trend regarding incidence of catheterization but
sion analysis show that mean CDPP decreased by 6.5 days developed a trend of decreasing incidence of catheteriza-
on the medical services and 5.6 days on the surgical ser- tion of 0.13% per month as well.
vices immediately after the intervention (P < .001) CDPP and incidence of catheterization stratified
(Table 2). The average preintervention monthly incidence according to age are shown in Table 3. The findings
of urinary catheterization was 14.5% for medical units were similar to those of the primary analysis, with

Figure 1. The two primary outcome parameters, mean catheter days per patient (CDPP) and monthly incidence of urinary
catheterization (% catheterized), for the two services measured over the study period. The transition period, indicated by the grey
regions, reflects the time required for the various interventions to take place and was not included in the statistical analysis. The
postintervention period begins immediately after this transition period.
4 NORMAN ET AL. 2017 JAGS

lasting effect on how healthcare providers use these


Table 2. Results of Segmented Regression Analysis
devices. The results show, after adjustment for baseline
Coefficient (95% trends, a marked and enduring decrease in the incidence of
Regression Model Confidence Interval) P-Value catheterization across the age spectrum, in many cases by
almost half. Furthermore, the duration of catheterization
Medicine decreased significantly for individuals who received a
Catheter days per patient
catheter, with a majority catheterized for 2 days or less
Baseline trend 1.34 ( 2.43 to 0.25) .018
Effect of intervention 6.52 ( 9.45 to 3.58) <.001 after the intervention. These findings have several positive
Trend change 1.31 (0.21–2.40) .021 implications for delivering high-quality hospital care.
after intervention We observed a significant decrease in the incidence of
Monthly incidence of catheterization, percent urinary catheterization after our intervention. Multiple
Baseline trend 0.12 ( 0.18 to 0.06) <.001 previous studies have examined the effect of educational
Effect of intervention 3.03 ( 5.00 to 1.06) .004 interventions on urinary catheter use.12,20–27 Several of
Surgery these studies focused on interventions introduced on an
Catheter days per patient
individual unit or service, limiting a direct comparison
Baseline trend 0.34 ( 0.59 to 0.09) .008
Effect of intervention 5.64 ( 6.31 to 4.97) <.001 with this work, which introduced an intervention across a
Trend change 0.34 (0.09–0.59) .010 whole hospital. Another study28 found an approximately
after intervention 63% reduction in the incidence of urinary catheterization
Monthly incidence of catheterization, percent across a cohort of internal medicine patients exposed to an
Effect of intervention 6.35 ( 8.91 to 3.80) <.001 intervention incorporating a more-restrictive catheteriza-
Trend change 0.13 ( 0.21 to 0.05) .002 tion policy. Similarly, a 51% reduction in the incidence of
after intervention urinary catheterization on admission was found in individ-
uals admitted to a general internal medicine service after
introducing order entry and nursing order changes.29 For
CDPP and incidence of catheterization dropping in the surgical services, a 48% reduction was observed in the
postintervention period in all age groups. Older adults incidence of catheterization on an orthopedics unit after
were catheterized more frequently. By the end of the fol- introducing a protocol incorporating evidence-based indi-
low-up period, CDPP had decreased by 7.6 to 14.3 days cations for catheterization,30 whereas a more-modest 14%
(64–86%) on the medical services and 5.5 to 12.7 days reduction in urinary catheterization was found postopera-
(38–78%) on the surgical services depending on age group. tively after posters and educational sessions were intro-
The incidence of catheterization similarly decreased by duced.31 The results presented here were similar in
35% to 52% on the medical services and 38% to 50% on magnitude to those of the other studies, with incidence of
the surgical services by the end of the study period. The catheterization decreasing by 35% to 52%, and lend fur-
histograms of pre- and postintervention CDPP are shown ther credence to the value of the approaches incorporated
in Figure 2. Before the intervention, the proportion of indi- in our intervention and those of others. Our study also
viduals catheterized for 2 days or less was 12% for medi- demonstrates that these benefits are generalizable to a
cine and 8% for surgery. A marked change in the mixed population of medical and surgical patients.
distribution was observed after the intervention, with 51% Many previous studies of urinary catheterization have
and 44% catheterized for 2 days or less respectively. focused on its role as a risk factor for the development of
catheter-associated UTI (CAUTI), particularly if a catheter
remains in place for long periods.6 Although we did not
DISCUSSION
examine CAUTI as an outcome measure, we examined a
This study demonstrates that a multimodal educational related measure, CDPP. Studies examining CAUTI have
intervention encouraging evidence-based use of urinary estimated that, after the first 48 hours of urinary catheteri-
catheters in an entire hospital can have an immediate and zation, each additional day increases the risk of CAUTI by

Table 3. Outcome Measures According to Age


<65 65–74 75–84 ≥85
Outcome Measure
Medicine Surgery Medicine Surgery Medicine Surgery Medicine Surgery

Catheter days per patient, mean  standard deviation


Before intervention 16.7  15.9 8.5  10.4 11.8  12.6 8.9  13.3 17.0  14.9 11.6  10.4 10.8  7.5 16.3  9.9
After intervention 4.9  10.9 2.9  1.7 2.5  1.5 2.9  2.5 4.7  5.7 4.0  2.3 3.6  2.9 3.5  2.0
After second phase 4.6  4.6 2.6  2.4 5.4  10.6 3.0  2.7 5.6  7.0 3.2  4.0 3.8  3.1 3.9  2.4
End of study period 2.4  1.3 2.9  4.3 4.2  3.8 3.4  2.0 3.9  5.5 3.3  2.6 2.9  4.3 3.6  2.9
Catheterized, %
Before intervention 8.6 15.9 14.3 27.2 14.7 31.1 27.1 32.0
After intervention 4.3 12.1 7.6 20.2 17.2 21.3 22.3 24.2
After second phase 3.8 8.7 10.5 12.2 13.2 17.4 12.7 17.2
End of study period 4.1 8.7 9.3 13.6 9.6 19.2 14.1 16.5
JAGS 2017 REDUCING URINARY CATHETER USE IN HOSPITALS 5

Figure 2. Histograms of catheter use in the 6-month preintervention period and the 6-month postintervention period immediately
after the transition period. Because of differences in patient volumes between services, the scale varies between the plots.

5% to 10%.2 If a urinary catheter is necessary, the dura- strict (see the Centers for Disease Control and Prevention
tion of catheterization should hence be minimized, ideally guidelines16 for supported indications), the continued dis-
to less than 48 hours,2,16 a period during which the indi- parity between younger and older individuals suggests that
vidual is at essentially no greater risk of infection than there may be further opportunity for improvement. We
someone who was not catheterized.2,12 Although we have introduced additional interventions as an ongoing
observed a greater reduction in CDPP than in a previous component of this work, including automated stop
study involving individuals undergoing surgery,12 the abso- orders,33 daily catheter rounds to review ongoing catheter-
lute CDPP of 2.2 days reported in that study was lower izations,34 and an Acute Care for Elders orderset,35 avail-
than for surgical inpatients at our hospital. This suggests able to all older adults admitted to the General Internal
that, although our intervention had a significant effect, Medicine service.
there may be room for improvement. A study of 2,965 One additional concern that this study addressed is
U.S. acute care hospitals demonstrated that their CDPP for whether the changes in catheter use identified immediately
individuals undergoing surgery averaged 3.5 days,2 versus after intervention wane with time, requiring further inter-
2.9 days at the end of the study period at our hospital, vention. Other studies have suggested that multiple inter-
suggesting that it is an above-average performer. ventions may be necessary to maintain adherence.36 The
The proportion of individuals catheterized for analysis presented here, which includes almost 3 years of
48 hours or less also dramatically increased after the inter- follow-up, has not identified evidence that this is the case.
vention at our hospital. A cohort of individuals with The segmented regression approach, which specifically
extended catheterizations, in some cases 15 days or more, tests for any ongoing linear trends in the outcomes of
were far less numerous (Figure 2) after the intervention. interest, did not identify any meaningful trends suggestive
Although it is difficult to confirm the reasons behind these of a reversion to previous behaviors after the initial inter-
previous lengthy urinary catheterizations, it is possible that vention, although there were further second-phase inter-
this subgroup may at least in part have consisted of indi- ventions deployed in 2011 that may have served to
viduals whose urinary catheter was left in place for longer reinforce behaviors. The hospital is continuing surveillance
than necessary. of the parameters described here to observe whether repeat
We observed a higher frequency of urinary catheter interventions are necessary.
use in older adults, particularly those aged 85 and older. This study has several limitations. One area of uncer-
This has been well demonstrated.7,8 Although we did not tainty is what the potential unintended consequences of not
have the opportunity to audit reasons for individual cathe- catheterizing are. One common concern is whether these
ter placements, previous research suggests that, in many interventions result in greater use of other continence man-
cases, older adults may be inappropriately catheterized.2,14 agement approaches, particularly depending more on the
We observed a marked reduction in catheter use in older use of incontinence products, which are expensive. Although
adults after our intervention, which aimed to educate pro- this was not explicitly examined at our hospital, we are not
viders on appropriate indications for catheterization. The aware of any significant increases in the use of incontinence
rates at the end of the study period in our hospital products. A second limitation of our study is that we did not
(Table 3) compares favorably with estimates collected have a control group to compare our results with. This is
from 183 U.S. hospitals, which found that 23.6% of all largely a consequence of the design of the educational inter-
inpatients are catheterized.32 Given that the indications for vention, which emphasized word-of-mouth spread and
catheterization are the same for all patients and are quite changes to the hospital’s EMR, making it difficult to isolate
6 NORMAN ET AL. 2017 JAGS

an area of the hospital from the intervention, although the 10. Saint S, Lipsky BA, Baker PD et al. Urinary catheters: What type do men
and their nurses prefer? J Am Geriatr Soc 1999;47:1453–1457.
use of segmented regression allowed us to test for secular
11. Tiwari MM, Charlton ME, Anderson JR et al. Inappropriate use of urinary
trends in our data suggestive of exogenous factors, of which catheters: A prospective observational study. Am J Infect Control
none were found. A third limitation of this study is that we 2012;40:51–54.
were unable to differentiate the relative effectiveness of the 12. Wald HL, Kramer AM. Feasibility of audit and feedback to reduce postop-
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13. Reilly L. Reducing Foley catheter device days in an intensive care unit:
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of this study is that we did not have access to individual among older hospitalized patients without a specific medical indication for
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15. Hu FW, Yang DC, Huang CC et al. Inappropriate use of urinary catheters
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appropriately and whether there was any change in behavior 16. Gould C, Umscheid C, Agarwal R et al. Healthcare Infection Control Prac-
tices, Advisory Committee. Guideline for prevention of catheter-associated
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care units in argentina. Infect Control Hosp Epidemiol 2004;25:47–50.
Conflict of Interest: None of the authors have any actual 23. French GL, Cheng AF, Wong SL et al. Repeated prevalence surveys for
monitoring effectiveness of hospital infection control. Lancet 1989;2:1021–
or potential conflicts of interest to declare with respect to
1023.
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Author Contributions: Dr. Norman and Dr. Sinha associated urinary tract infection in the zero-tolerance era. Am J Infect
designed the study, collected and analyzed the data, and Control 2011;39:817–822.
25. Oman KS. Nurse-directed interventions to reduce catheter-associated uri-
prepared the manuscript. Ms. Ramsden and Ms. Ginty
nary tract infections. Am J Infect Control 2012;40:548–553.
developed the educational interventions and delivered the 26. Gotelli JM. A quality improvement project to reduce the complications
front-line education sessions. associated with indwelling urinary catheters. Urol Nurs 2008;28:465.
Sponsor’s Role: There was no external sponsor for this 27. Leis JA, Corpus C, Rahmani A et al. Medical directive for urinary catheter
removal by nurses on general medical wards. JAMA Intern Med
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28. Shimoni Z, Rodrig J, Kamma N et al. Will more restrictive indications
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