First Approach

US Population 209000000 209000000

Overweight
Individuals 34% 71060000
Trying to lose
weight 35.00% 24871000.00
Comfortable with
weight loss drugs 15% 3730650

First Approach Gross margin $24,8

Percentage
Year Customer Captured First supply Second Supply
Captured
1 373065.00 10% $9,252,012.00 $5,551,207.20
2 559597.50 15% $13,878,018.00 $8,326,810.80
3 746130.00 20% $18,504,024.00 $11,102,414.40
4 932662.50 25% $23,130,030.00 $13,878,018.00
5 1119195.00 30% $27,756,036.00 $16,653,621.60

First Approach Gross Margin $58,13

Percentage
Year Customer Captured Captured First Supply Second Supply
1 373065.00 10% $21,686,268.45 $13,011,761.07
2 559597.50 15% $32,529,402.68 $19,517,641.61
3 746130.00 20% $43,372,536.90 $26,023,522.14
4 932662.50 25% $54,215,671.13 $32,529,402.68
5 1119195.00 30% $65,058,805.35 $39,035,283.21

First Approach Gross Margin $74,8

Percentage
Year Customer Captured First Supply Second Supply
Captured
1 373065.00 10% $27,905,262.00 $16,743,157.20
2 559597.50 15% $41,857,893.00 $25,114,735.80
3 746130.00 20% $55,810,524.00 $33,486,314.40
4 932662.50 25% $69,763,155.00 $41,857,893.00
5 1119195.00 30% $83,715,786.00 $50,229,471.60

Second Approach
US Population 209000000 209000000
Overweight
Individuals 34% 71060000
Ready to request
prescription 12% 8527200

Second Approach Gross margin $24,8

Percentage
Year Customer Captured First Supply Second Supply
Captured
1 852720.00 10% $21,147,456.00 $12,688,473.60
2 1279080.00 15% $31,721,184.00 $19,032,710.40
3 1705440.00 20% $42,294,912.00 $25,376,947.20
4 2131800.00 25% $52,868,640.00 $31,721,184.00
5 2558160.00 30% $63,442,368.00 $38,065,420.80

Second Approach Gross Margin $58,13

Percentage
Year Customer Captured First Supply Second Supply
Captured
1 852720.00 10% $49,568,613.60 $29,741,168.16
2 1279080.00 15% $74,352,920.40 $44,611,752.24
3 1705440.00 20% $99,137,227.20 $59,482,336.32
4 2131800.00 25% $123,921,534.00 $74,352,920.40
5 2558160.00 30% $148,705,840.80 $89,223,504.48

Second Approach Gross Margin $74,8

Percentage
Year Customer Captured First Supply Second Supply
Captured
1 852720.00 10% $63,783,456.00 $38,270,073.60
2 1279080.00 15% $95,675,184.00 $57,405,110.40
3 1705440.00 20% $127,566,912.00 $76,540,147.20
4 2131800.00 25% $159,458,640.00 $95,675,184.00
5 2558160.00 30% $191,350,368.00 $114,810,220.80

Third Approach
Ideal Target 4300000

Third Approach Gross margin $24,8

Percentage
Year Customer Captured First Supply Second Supply
Captured
1 1290000.00 30% $31,992,000.00 $19,195,200.00
 2 1505000.00 35% $37,324,000.00 $22,394,400.00
3 1720000.00 40% $42,656,000.00 $25,593,600.00
4 1935000.00 45% $47,988,000.00 $28,792,800.00
5 2150000.00 50% $53,320,000.00 $31,992,000.00

Third Approach Gross Margin $58,13

Percentage
Year Customer Captured First Supply Second Supply
Captured
1 1290000.00 30% $74,987,700.00 $44,992,620.00
2 1505000.00 35% $87,485,650.00 $52,491,390.00
3 1720000.00 40% $99,983,600.00 $59,990,160.00
4 1935000.00 45% $112,481,550.00 $67,488,930.00
5 2150000.00 50% $124,979,500.00 $74,987,700.00

Third Approach Gross Margin $74,8

Percentage
Year Customer Captured First Supply Second Supply
Captured
1 1290000.00 30% $96,492,000.00 $57,895,200.00
2 1505000.00 35% $112,574,000.00 $67,544,400.00
3 1720000.00 40% $128,656,000.00 $77,193,600.00
4 1935000.00 45% $144,738,000.00 $86,842,800.00
5 2150000.00 50% $160,820,000.00 $96,492,000.00
 Investment

R&D $400,000,000.00

Overhead $1,200,000.00

Marketing Budget $23,000,000.00

Total $424,200,000.00

Full Cycle Total Manufacturers gross

margin
$1,110,241.44 $15,913,460.64 Option 1 $24.80
$1,665,362.16 $23,870,190.96 Option 2 $58.13
$2,220,482.88 $31,826,921.28 Option 3 $74.80
$2,775,603.60 $39,783,651.60
$3,330,724.32 $47,740,381.92
Total $159,134,606.40
ROI -62.49%

Full Cycle Total

$2,602,352.21 $37,300,381.73
$3,903,528.32 $55,950,572.60
$5,204,704.43 $74,600,763.47
$6,505,880.54 $93,250,954.34
$7,807,056.64 $111,901,145.20
Total $373,003,817.34
ROI -12.07%

Full Cycle Total

$3,348,631.44 $47,997,050.64
$5,022,947.16 $71,995,575.96
$6,697,262.88 $95,994,101.28
$8,371,578.60 $119,992,626.60
$10,045,894.32 $143,991,151.92
Total $479,970,506.40
ROI 13.15%
 Full Cycle Total
$2,537,694.72 $36,373,624.32
$3,806,542.08 $54,560,436.48
$5,075,389.44 $72,747,248.64
$6,344,236.80 $90,934,060.80
$7,613,084.16 $109,120,872.96
Total $363,736,243.20
ROI -14.25%

Full Cycle Total

$5,948,233.63 $85,258,015.39
$8,922,350.45 $127,887,023.09
$11,896,467.26 $170,516,030.78
$14,870,584.08 $213,145,038.48
$17,844,700.90 $255,774,046.18
Total $852,580,153.92
ROI 100.99%

Full Cycle Total

$7,654,014.72 $109,707,544.32
$11,481,022.08 $164,561,316.48
$15,308,029.44 $219,415,088.64
$19,135,036.80 $274,268,860.80
$22,962,044.16 $329,122,632.96
Total $1,097,075,443.20
ROI 159%

Full Cycle Total

$3,839,040.00 $55,026,240.00
 $4,478,880.00 $64,197,280.00
$5,118,720.00 $73,368,320.00
$5,758,560.00 $82,539,360.00
$6,398,400.00 $91,710,400.00
Total $366,841,600.00
ROI -14%

Full Cycle Total

$8,998,524.00 $128,978,844.00
$10,498,278.00 $150,475,318.00
$11,998,032.00 $171,971,792.00
$13,497,786.00 $193,468,266.00
$14,997,540.00 $214,964,740.00
Total $859,858,960.00
ROI 103%

Full Cycle Total

$11,579,040.00 $165,966,240.00
$13,508,880.00 $193,627,280.00
$15,438,720.00 $221,288,320.00
$17,368,560.00 $248,949,360.00
$19,298,400.00 $276,610,400.00
Total $1,106,441,600.00
ROI 161%