Electron microscope

Electron microscopy (EM) has become an extremely popular method for the
ultrastructural study of macromolecules, cells and tissues. An aqueous biological
sample is frozen rapidly and irradiated with a beam of electrons. A detector
senses how the electrons are scattered and a computer reconstructs the 3D-
shape of the molecule.
Why you need this service?
• You have small amount of materials;
• The material is hard to crystallize;
• You are looking into the molecules in atomic details;
• It is a large biomolecular complex (>150 kDa, up to 2000 Å);
• You want to observe the real "native state" structure.

https://www.creative-biostructure.com/cryo-em-services_4.htm