Bacilli inoculum (lung, GI

tract,lymph nodes,skin)

Contiguous Orificial TB
spread an/or and/or
autoinculation scrofuloderma
Primary TB
Chancre Host with poor
Primary TB complex immunity Acute
(Ranke :Nodule, lymphagitis, milliary TB
adenitis)
Hematogenous
Host with good to desemination
moderate immunity Extrapulmonar
TB

PPD positive
Orificial TB, TB
fungosa serpiginosa

Tuberculoid granuloma
CTB
with/without necrosis (Ghon)
Tuberculids
Fibrosis

Endogenous Complete
stabilization Secondary TB
reactivation healing
Factor of
immunosuppression
(diabetes, cancer, etc)

Exogenous reinoculation