Generic Name : Hydralazine

Brand Name : Apresoline

Dosage : 5 mg/dose then 5-10 mg every 20-30 minutes as needed

Indication : Pre-eclampsia /eclampsia

Mechanism of Action Side Effects Contraindication Adverse Reaction Nursing Consideration

Hydralazine Headache, pounding/fast Contraindicated to pt.s CNS: peripheral >Assess blood pressure
heartbeat, loss of hypersensitive to the neuritis, headache, before starting therapy
↓ appetite, nausea, drug and any of its dizziness and regularly thereafter.
Directly relaxes vomiting, diarrhea, or
component and in
dizziness may occur as >Instruct client to take
arteriolar smooth those with coronary CV: orthostatic
your body adjusts to the oral form with meals.
muscle medication. artery disease or mitral hypotension,
↓ valvular rheumatic tachycardia,
Vasodilaion >Inform client that
heart disease. arrythmias, angina,
↓ orthostatic hypotension
palpitations.
Lowers Blood can be minimized by
Use cautiously in
Pressure GI: n/v, diarrhea, rising slowly and not
patients with
anorexia changing position
suspected cardiac
suddenly.
disease, CVA, or
Hematologic:
severe renal
neutropenia, >Tell pt. not to abruptly
impairment, and in
leukopenia, stop taking drug, but to
those taking other
agranulocytopenia call prescriber if adverse
antihytensives.
reaction occurs.
Metabolic: weight
gain, sodium >Tell client to limit
retention sodium intake.

Skin: rash
Generic Name : Phytomenadione

Brand Name : Vitamin K

Dosage : 0.1 cc via IM to the Vastus Lateralis of the newborn

Indication : To stimulate the clotting factors of the newborn

Mechanism of Action Side Effects Contraindication Adverse Reaction Nursing Consideration

Sterility of GI tract May be transient flushing Contraindicated to those The synthetic Ensure that the
↓ of the face, sweating, a who are form of Vitamin K adequate dose is given
Administration of sense of constriction of hypersensitive to any and Vitamin K3 while following the
Vitamin K the chest, and weakness. component of Vitamin (Menadione) can proper IM Drug
↓ Cramp-like pain, weak and K containing products. cause allergic Administration.
Increased Synthesis rapid pulse, convulsive reaction, Hemolytic
of precursor movements, chills and Anemia, and >Apply pressure to the
proteins in the GIT fever, hypotension, Cytotoxicity in injection site to prevent
mainly factors II, cyanosis, or liver cells. further bleeding.
VII, IX, and X are hemoglobinuria has been
produced and reported occasionally. >Document the giving
increased. of the medication to
↓ newborn to prevent an
From 30-60% accidental doubling of
compared to adult the dose.
clotting factor
values, blood
clotting factors
increase
Assessment Nursing Diagnosis Scientific Goals Interventio Rationale Evaluation
Background