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TOTAL VOLUME FLUID RESUSCITATION IN EMERGENCY ASSOCIATED

WITH OUTCOMES OF POST OPERATIVE INTRA-ABDOMINAL SEPSIS


PATIENTS IN INTENSIVE CARE UNIT

Edwin Yoshua L. Toruan, Vera Irawany


General Practitioner, Fatmawati Hospital, Jakarta Selatan
Intensive Care Unit Consultant, Fatmawati Hospital, Jakarta Selatan

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host


response to infection.1 Intra-abdominal sepsis represents the host’s systemic inflammatory
response to bacterial peritonitis.2
The incidence of intra-abdominal sepsis occurs in Indonesia especially in Jakarta has
not been established since its research is limited. However, in the Intensive Care Unit of
Fatmawati Hospital, the admission of the patient with intra-abdominal sepsis is increasing, with
50% of the cases results in mortality.
Fluid therapy is fundamental to the acute resuscitation of critically ill patients,
especially in sepsis patients. In general, however, early and appropriate goal-directed fluid
therapy contributes to a degree of fluid overload in most if not all patients. Recent data imply
that a threshold may exist beyond which, after acute resuscitation, additional fluid therapy may
cause harm.
In this study, we conduct a retrospective study in patients admitted to Intensive Care
Unit with intra-abdominal sepsis during a six-month period. We collected data on patients
during their admission to emergency and undergo the laparotomy within 24 hours, the total
volume fluid resuscitation given to the patients during the time in emergency, and the outcome
after patients admitted to ICU after the surgery. The outcome here is whether the patient
discharged from ICU or the patient deteriorates poorly and therefore increasing the mortality
rate of ICU.
We aim and we hope that this study could prove that the total volume fluid resuscitation
given to this patient is associated with the outcome of the patients with intra-abdominal sepsis
who undergo surgery.

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