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Gene therapy can be broadly defined as the transfer of genetic material to cure a disease or at least to improve the clinical status
of a patient.
Introduction
Gene therapy is a technique for correcting defective genes responsible
for disease development. Researchers may use one of
several approaches for correcting faulty genes:
A normal gene may be inserted into a nonspecific location
within the genome to replace a nonfunctional gene. This approach
is most common.
An abnormal gene could be swapped for a normal gene
through homologous recombination.
The abnormal gene could be repaired through selective reverse
mutation, which returns the gene to its normal function.
Gene therapy is the insertion, alteration, or removal of genes
within an individual's cells and biological tissues to treat diseases.
It is a technique for correcting defective genes that are
responsible for disease development.
GENE THERAPY
History of Gene Therapy
It is diffi cult to pinpoint the beginning of gene therapy, but 1967 can be considered
as the beginning of at least the discussion about gene therapy