NASHIK GRAMIN SHIKSHAN PRASARAK MANDAL’S

COLLEGE OF PHARMACY
BRAHMA VALLEY EDUCATIONAL CAMPUS
TRIMBAK ROAD, ANJANERI, NASHIK-422 213
Third Sessional Practical Examination (2012-13)
SUBJECT: Pharmacology -III CLASS: Final Year B. Pharm.

Date : 13/03/13 Marks : 20

Q. 1 Synopsis
a) Define Immunosuppresants with examples 02
b) Find out the P – values if i) t is 2.89 and degrees of freedom 8
ii) t is 3.4 and degrees of freedom 12 02
c) Define i) Degrees of freedom and ii) Median 01

Q. 2. Case Study

Mrs. Oberoi, 42 years is suffering from insulin dependent diabetes (IDDM ) for the past 20
years. Her glycarmic control was initially poor but has improved very much because of her
treatment and dietary control. Recently, she has developed blood pressure and her blood pressure
in the recent visits to the doctor has shown to be 165/95 mm Hg. She has proteinuria as well. Mrs
Oberoi is a nonsmoker and does not overweigh and also on controlled diet.

Discuss the management strategy for recently diagnosed diabetes and hypertensive. 04

Q. 3 Carry out the critical appraisal of the given Fixed dose combination 05

…………………………………………………………

Q. 4 The following table shows the serum urate levels (mg/ 100 ml ) in 6 normal and 6 patients
suffering from gout. Whether these changes are significant or not can be noted by calculating
the t value. 06

Subjects (n) Serum urate levels (mg/100 ml)

Normal Gout patient
1 4.5 6.2
2 4.1 12.0
3 6.2 8.1
4 4.3 8.9
5 4.6 8.3
6 3.8 9.4