DRUG INDEX

General Data
Patient number:
Name:
Age/sex:
Date of admission:
Date of discharge:
Attending physician:
Admitting diagnosis:

GENERIC/
DOSAGE MODE OF ACTION INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS
BRAND NAME
Co Amoxiclav 1.2 g tiv q 8 Amoxicillin is a semisynthetic penicillin Co-amoxiclav is indicated Hypersensitivity to the The most commonly
(beta-lactam antibiotic) that inhibits one for the treatment of the active substances, to reported adverse drug
or more enzymes (often referred to as following infections in any of the penicillins or reactions (ADRs) are
penicillin-binding proteins, PBPs) in the adults and children to any of the excipients. diarrhoea, nausea and
biosynthetic pathway of bacterial • Acute bacterial sinusitis History of a severe vomiting.
peptidoglycan, which is an integral (adequately diagnosed) immediate
structural component of the bacterial • Acute otitis media hypersensitivity reaction
cell wall. Inhibition of peptidoglycan
• Acute exacerbations of (e.g. anaphylaxis) to
synthesis leads to weakening of the cell
chronic bronchitis another beta-lactam
wall, which is usually followed by cell
lysis and death. (adequately diagnosed) agent (e.g. a
Amoxicillin is susceptible to • Community acquired cephalosporin,
degradation by beta-lactamases pneumonia carbapenem or
produced by resistant bacteria and • Cystitis monobactam).
therefore the spectrum of activity of • Pyelonephritis History of
amoxicillin alone does not include • Skin and soft tissue jaundice/hepatic
organisms which produce these infections in particular impairment due to
enzymes. cellulitis, animal bites, amoxicillin/clavulanic
Clavulanic acid is a beta-lactam severe dental abscess with acid.
structurally related to penicillins. It spreading cellulitis.
inactivates some beta-lactamase • Bone and joint infections,
enzymes thereby preventing in particular osteomyelitis.
inactivation of amoxicillin. Clavulanic Consideration should be
acid alone does not exert a clinically given to official guidance
useful antibacterial effect.
 on the appropriate use of
antibacterial agents.
Moxifloxacin HCl 1 drop every Inhibits DNA gyrase and Antibiotic/ Quinolone Hypersensitivity to Transient ocular
2 hours on topoisomerase IV. This results in moxifloxacin or to other discomfort, burning &
the right eye inhibition of DNA replication and quinolones stinging. Ocular pain,
translation and DNA repair, pruritus & hyperemia.
recombination and transposition, Headache, keratitis,
which causes bacterial cell death. pharyngitis
&subconjunctival
hemorrhage.
Prednisolone 1 drop every Decreases inflammation by Steroid responsive Acute, untreated Increase intraocular
3 hours on suppression of PMN’s and reversal inflammation of the purulent ocular pressure with optic
the right eye of increased capillary permeability palpebral and bulbar, infections. Acute nerve damage and
cornea and anterior superficial herpes visual field defects.
segment simplex, varicella and Posterior sub capsular
most other viral cataract formation
diseases of the cornea secondary ocular
and conjunctiva infection from fungi or
viruses
Dexpanthenol 1 drop into Relieving dry skin, preventing and Corneal erosions; do not use with contact Occasionally, symptoms
gel conjunctival treating sore nipples during breast- supportive and post lenses. May cause of intolerance
sac 3-5 feeding, and promoting healing of treatment of all types of transient blurring of
times/day burns and poorly-healing wounds. keratitis; scald burns; vision and caution when
and before dystrophic corneal driving or operating
retiring diseases; prevention and machines
treatment of corneal
damage in wearer’s of
contact lenses
Omeprazole 40 mg cap, 1 Proton pump inhibitors act by  Dyspepsia Hypersensitivity to This may be due to its
cap 30 mins irreversibly blocking  Peptic ulcer disease omeprazole longer availability and,
before the hydrogen/potassium adenosine hence, clinical
 Gastroesophageal
breakfast triphosphatase enzyme system (the experience. Common
+ + reflux disease (GERD
H /K ATPase, or, more commonly, adverse effects
or GORD)
the gastric proton pump) of the include: headache, nau
gastric parietal cells  Laryngopharyngeal sea, diarrhea, abdomina
reflux l pain, fatigue,
 Barrett's esophagus and dizziness
 Eosinophilic
esophagitis
 Stress gastritis preven
tion
 Gastrinomas and
 other conditions that
cause hypersecretion
of acid
 Zollinger-Ellison
syndrome (often 2-3x
the regular dose is
required as compared
to the other
indications)

Clerk-in-Charge