OD at 405nm

0.00
0.25
0.50
0.75
1.00
1.25
1.50
1.75
2.00
2.25
2.50
2.75
3.00
3.25

C
on
tr
ol
6
6h h A
R dr
C
0.
01
1
18 8h
h A
R dr
C
0.
01

CDDE data: Adriamycin (25mg/kg)

24 24h
h
R Ad
C r
0.
01
36
36 h
h A
R dr
C
0.
01
48
48 h
h A
R dr
C

Adriamycin (25mg/kg) + Resv.Cu (0.01 mg/kg)

0.
01
60 0h6
h A
R dr
C
0.
01
72
72 h
h A
Adr-RC.01 CDDE

R dr
C
0.
01
96
96 h
h A
R dr
C
0.
01
12
12 0
0h h A
R dr
C
0.
01
14
14 4
4h h A
R dr
C
0.
01
16
16 8
8h h A
R dr
C
0.
01
 Adr- RC 1 - CDDE
3.25

3.00

2.75

2.50

2.25

2.00
OD at 405nm

1.75

1.50

1.25

1.00

0.75

0.50

0.25

0.00
l r 1 r 1 r 1 r 1 r 1 r 1 r 1 r 1 r 1 r 1
ro Ad RC dr C 1 Ad C Ad RC Ad RC Ad RC Ad RC Ad RC Ad RC Ad RC Ad RC
nt h A R h R h h h h h h h h
Co 6 6h h
18 18h 24 4h 36 36h 48 48h 60 0h 72 72h 96 96h 0
12 120
h 4
14 144
h 8
16 168
h
2 6

CDDE data: Adriamycin (25mg/kg)

Adriamycin (25mg/kg) + Resv.Cu (1 mg/kg)