Kezia Elian Devina

472016031

HubungaRiboflavin dan MTHFR

Pengertian dan fungsi riboflavin1. Pengertian MTHFR2. Mutasi pada MTHFR C677T3.
Hubungan MTHFR dengan riboflavin4. Asupan gizi yang dapat membantu menghambat
mutasi MTHFR C677T5.

1
Eussen, S. J., Vollset, S. E., Hustad, S., Midttun, Ø., Meyer, K., Fredriksen, Å., ... & Overvad, K.
(2010). Plasma Vitamins B2, B6, and B12, and Related Genetic Variants as Predictors of Colorectal
Cancer Risk. Cancer Epidemiology and Prevention Biomarkers, 19(10), 2549-2561.
2
Moat, S. J., Ashfield-Watt, P. A., Powers, H. J., Newcombe, R. G., & McDowell, I. F. (2003). Effect
of riboflavin status on the homocysteine-lowering effect of folate in relation to the MTHFR (C677T)
genotype. Clinical chemistry, 49(2), 295-302.
3
Ward, M., Wilson, C. P., Strain, J. J., Horigan, G., Scott, J. M., & McNulty, H. (2011). B-Vitamins,
Methylenetetrahydrofolate Reductase (MTHFR) and Hypertension. International Journal for Vitamin
and Nutrition Research, 81(4), 240-244.
4
García-Minguillán, C. J., Fernandez-Ballart, J. D., Ceruelo, S., Ríos, L., Bueno, O., Berrocal-
Zaragoza, M. I., ... & Murphy, M. M. (2014). Riboflavin Status Modifies The Effects of
Methylenetetrahydrofolate Reductase (MTHFR) and Methionine Synthase Reductase (MTRR)
Polymorphisms on Homocysteine. Genes & nutrition, 9(6), 435.
5
van den Donk, M., Buijsse, B., van den Berg, S. W., Ocké, M. C., Harryvan, J. L., Nagengast, F. M.,
... & Kampman, E. (2005). Dietary intake of folate and riboflavin, MTHFR C677T genotype, and
colorectal adenoma risk: a Dutch case-control study. Cancer Epidemiology and Prevention
Biomarkers, 14(6), 1562-1566.